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The map label for this gene is obgE [H]

Identifier: 113969241

GI number: 113969241

Start: 1047700

End: 1048866

Strand: Direct

Name: obgE [H]

Synonym: Shewmr4_0897

Alternate gene names: 113969241

Gene position: 1047700-1048866 (Clockwise)

Preceding gene: 113969240

Following gene: 113969242

Centisome position: 22.26

GC content: 48.24

Gene sequence:

>1167_bases
ATGAAGTTTGTCGATGAGGCAGTAATTAGGGTCGAAGCAGGCGACGGCGGTAGCGGTTGTGTGAGCTTCAGACGCGAAAA
ATATATCCCCGATGGTGGTCCTGATGGTGGTGATGGCGGTGACGGCGGCAGTGTTTATCTGCAGGCCGATGAAAACCACA
ACACCCTGATAGAATACCGATTTGAACGTTTTCACATGGCTGAGCGCGGTGAAAACGGCCGTGGCCGTGATTGTACTGGT
CACAGCGGTAAAGATTTGATTTTAAAAGTGCCAGTGGGTACTCGTGCCATTGATGATGAAACCGAGGAAGTCCTCGGCGA
TTTAACCACCCATGGCCAAAAGCTATTAGTGGCTAAAGGTGGATTTCACGGCTTAGGCAATACGCGCTTTAAGAGCAGTA
CTAACCGTGCGCCACGTCAAAAGACCTTAGGTACTCCGGGTGAAGTCCGTAGTCTGAAATTAGAGCTGCTGTTGTTAGCC
GACGTTGGCTTGCTCGGTATGCCTAACGCGGGTAAATCGACCTTTATTCGCGCGGTATCACGTGCAACACCAAAGGTTGC
CGATTACCCCTTCACGACGTTAGTACCTAACCTAGGTGTGGTTAACCCTCGCCCTGGTCAAAGCTTTGTGATCGCCGATA
TTCCAGGTTTGATCGAAGGCGCGGCAGAAGGTGCGGGTCTGGGTATTCGTTTCTTAAAACATTTAGAACGTTGCCGTATT
CTGTTGCATATCATCGATATCGAGCCAATTGATGGCACAGATCCTGTGGATTCTGCTCGTGCGATCGTCGGTGAGCTTGA
AAAATATTCGCCCAAATTGGCAAGCAAGCCACGTTGGTTAGTCTTTAACAAGGCCGATCTGCTGCTCGAAGATGAGCTGA
AAGAGAAAGTTGCTCGCGTAGTTAAGGAATTAGGTTGGGAAGGTGACGTTTACACTATTTCTGCCTATAGCCGCGATGGC
ACTAAAGAATTAGCGACCAAGCTGCTGGACTTCATCCAAAGTCTTCCTCCGGAAGATAAAGATGCGAACCCAGATGCAGA
GGTTGAGTTCAAGTGGGACAATTATCATCAAGCCAACATTGATGCAATCAATGAAGACTATGACGATGAATTTGACGATG
ACTTTGATGATGACGACTACGATGTAGAAGTGATCTACCAAAGATAA

Upstream 100 bases:

>100_bases
GGCGTTGACTGGTAAGATTGGGAGCAAGTATCTCGAGTTTTTTGGCGACCGATGAAGTTAAACGGTATAATTCCTTCATT
CAGTGATGCCTGGAGTAAGT

Downstream 100 bases:

>100_bases
TATCCCAACCTAAGTTTTGAGAGTCCCGTGTACGCAGATACTCAAAATGATATTACTCGGCAGGTTGTGCGTGTCGCACA
ACTGCTACTGGCCTACGGCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKFVDEAVIRVEAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLQADENHNTLIEYRFERFHMAERGENGRGRDCTG
HSGKDLILKVPVGTRAIDDETEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRI
LLHIIDIEPIDGTDPVDSARAIVGELEKYSPKLASKPRWLVFNKADLLLEDELKEKVARVVKELGWEGDVYTISAYSRDG
TKELATKLLDFIQSLPPEDKDANPDAEVEFKWDNYHQANIDAINEDYDDEFDDDFDDDDYDVEVIYQR

Sequences:

>Translated_388_residues
MKFVDEAVIRVEAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLQADENHNTLIEYRFERFHMAERGENGRGRDCTG
HSGKDLILKVPVGTRAIDDETEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRI
LLHIIDIEPIDGTDPVDSARAIVGELEKYSPKLASKPRWLVFNKADLLLEDELKEKVARVVKELGWEGDVYTISAYSRDG
TKELATKLLDFIQSLPPEDKDANPDAEVEFKWDNYHQANIDAINEDYDDEFDDDFDDDDYDVEVIYQR
>Mature_388_residues
MKFVDEAVIRVEAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLQADENHNTLIEYRFERFHMAERGENGRGRDCTG
HSGKDLILKVPVGTRAIDDETEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRI
LLHIIDIEPIDGTDPVDSARAIVGELEKYSPKLASKPRWLVFNKADLLLEDELKEKVARVVKELGWEGDVYTISAYSRDG
TKELATKLLDFIQSLPPEDKDANPDAEVEFKWDNYHQANIDAINEDYDDEFDDDFDDDDYDVEVIYQR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=328, Percent_Identity=40.5487804878049, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI111955139, Length=293, Percent_Identity=36.518771331058, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI111955063, Length=127, Percent_Identity=43.3070866141732, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=33.8582677165354, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI58761500, Length=130, Percent_Identity=31.5384615384615, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789574, Length=364, Percent_Identity=68.956043956044, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=32.8125, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=326, Percent_Identity=38.9570552147239, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=321, Percent_Identity=31.4641744548287, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.15625, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=31.3559322033898, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=36.4197530864198, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=31.25, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=285, Percent_Identity=41.7543859649123, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585318, Length=289, Percent_Identity=38.4083044982699, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=29.9212598425197, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42732; Mature: 42732

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAVIRVEAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLQADENHNTLIEYR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEH
FERFHMAERGENGRGRDCTGHSGKDLILKVPVGTRAIDDETEEVLGDLTTHGQKLLVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLADVGLLGMPNAGKSTFIRAVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHEEEEEEEEECCCEECCCCCCHHHHHHHHH
RATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRI
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHEE
LLHIIDIEPIDGTDPVDSARAIVGELEKYSPKLASKPRWLVFNKADLLLEDELKEKVARV
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHH
VKELGWEGDVYTISAYSRDGTKELATKLLDFIQSLPPEDKDANPDAEVEFKWDNYHQANI
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCC
DAINEDYDDEFDDDFDDDDYDVEVIYQR
CCCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEAVIRVEAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLQADENHNTLIEYR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEH
FERFHMAERGENGRGRDCTGHSGKDLILKVPVGTRAIDDETEEVLGDLTTHGQKLLVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLADVGLLGMPNAGKSTFIRAVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHEEEEEEEEECCCEECCCCCCHHHHHHHHH
RATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRI
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHEE
LLHIIDIEPIDGTDPVDSARAIVGELEKYSPKLASKPRWLVFNKADLLLEDELKEKVARV
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHH
VKELGWEGDVYTISAYSRDGTKELATKLLDFIQSLPPEDKDANPDAEVEFKWDNYHQANI
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCC
DAINEDYDDEFDDDFDDDDYDVEVIYQR
CCCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA