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The map label for this gene is btuR [H]

Identifier: 113969190

GI number: 113969190

Start: 1001537

End: 1002172

Strand: Direct

Name: btuR [H]

Synonym: Shewmr4_0846

Alternate gene names: 113969190

Gene position: 1001537-1002172 (Clockwise)

Preceding gene: 113969189

Following gene: 113969191

Centisome position: 21.28

GC content: 54.09

Gene sequence:

>636_bases
ATGACAGCAGAGAACGAAAAACAGCTCGACACCGAACAAGCGCAAATCAAGGCTGAACGCCATAAGGCGCGCCAGCAAAA
AGTGAAGGCGGGTGTGGACGCTAAAATTGCCGCCGCCCAAGAAGAAAAAGGCATTCTGCTGGTGCTCACAGGCAATGGCA
AAGGCAAGTCGACCTCAGGTTTTGGCACGGTTGCCCGCGCAGTGGGTCACGGCAAAAAAGCCGCGGTAGTGCAATTTATC
AAGGGCACATGGGAATGCGGTGAGCGTAATCTGCTTGAAGGTGCGGGCGTGGCATTTCATGTGATGGGCACCGGATTTAC
CTGGGAAACCCAAGACAGAGAAAAGGACACTGCCGCCGCTCTCGTGGCGTGGGATGCCGCCGAAGCCTTGCTTCAAGACG
AAAGTATTGATTGTGTGATGCTCGATGAACTGACCTATATGGTGAGTTACCATTACCTCGATGTGGAGCGGGTGCTCACG
GCGCTGAAAAACCGTCCGCCGATGCAGCATGTGATTATCACTGGCCGTGCTTGCCACCGCGCGATTATCGAACTGGCGGA
TACGGTTAGCGAAGTGCAGCCGATTAAACATGCCTTCGAAGCAGGCATTAAAGCGCAGCCGGGATTCGACTATTAA

Upstream 100 bases:

>100_bases
CTGGATCGTTTGGCCGATGTATTAGCCGAGCATCTCGATATGCAAAAACTTGCGTCCATTATAAATGCATAAGAATTAGC
AGTAGGAAGAACAGAAGATC

Downstream 100 bases:

>100_bases
ACAGTGCGGCTTAGGCGGATTGGTTACACCGCGAGCCGCCCTTTAAACCCCATTAGGGCTGTTGTTCCTCGGTAAAATCC
GTTAGCGTCACTATGGTTAG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTAENEKQLDTEQAQIKAERHKARQQKVKAGVDAKIAAAQEEKGILLVLTGNGKGKSTSGFGTVARAVGHGKKAAVVQFI
KGTWECGERNLLEGAGVAFHVMGTGFTWETQDREKDTAAALVAWDAAEALLQDESIDCVMLDELTYMVSYHYLDVERVLT
ALKNRPPMQHVIITGRACHRAIIELADTVSEVQPIKHAFEAGIKAQPGFDY

Sequences:

>Translated_211_residues
MTAENEKQLDTEQAQIKAERHKARQQKVKAGVDAKIAAAQEEKGILLVLTGNGKGKSTSGFGTVARAVGHGKKAAVVQFI
KGTWECGERNLLEGAGVAFHVMGTGFTWETQDREKDTAAALVAWDAAEALLQDESIDCVMLDELTYMVSYHYLDVERVLT
ALKNRPPMQHVIITGRACHRAIIELADTVSEVQPIKHAFEAGIKAQPGFDY
>Mature_210_residues
TAENEKQLDTEQAQIKAERHKARQQKVKAGVDAKIAAAQEEKGILLVLTGNGKGKSTSGFGTVARAVGHGKKAAVVQFIK
GTWECGERNLLEGAGVAFHVMGTGFTWETQDREKDTAAALVAWDAAEALLQDESIDCVMLDELTYMVSYHYLDVERVLTA
LKNRPPMQHVIITGRACHRAIIELADTVSEVQPIKHAFEAGIKAQPGFDY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=193, Percent_Identity=65.2849740932643, Blast_Score=269, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23033; Mature: 22902

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAENEKQLDTEQAQIKAERHKARQQKVKAGVDAKIAAAQEEKGILLVLTGNGKGKSTSG
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCC
FGTVARAVGHGKKAAVVQFIKGTWECGERNLLEGAGVAFHVMGTGFTWETQDREKDTAAA
HHHHHHHHCCCCHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCEEECCCCCCHHHHHH
LVAWDAAEALLQDESIDCVMLDELTYMVSYHYLDVERVLTALKNRPPMQHVIITGRACHR
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHH
AIIELADTVSEVQPIKHAFEAGIKAQPGFDY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TAENEKQLDTEQAQIKAERHKARQQKVKAGVDAKIAAAQEEKGILLVLTGNGKGKSTSG
CCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCC
FGTVARAVGHGKKAAVVQFIKGTWECGERNLLEGAGVAFHVMGTGFTWETQDREKDTAAA
HHHHHHHHCCCCHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCEEECCCCCCHHHHHH
LVAWDAAEALLQDESIDCVMLDELTYMVSYHYLDVERVLTALKNRPPMQHVIITGRACHR
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHH
AIIELADTVSEVQPIKHAFEAGIKAQPGFDY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]