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The map label for this gene is cobC [H]

Identifier: 113969183

GI number: 113969183

Start: 993679

End: 994401

Strand: Direct

Name: cobC [H]

Synonym: Shewmr4_0839

Alternate gene names: 113969183

Gene position: 993679-994401 (Clockwise)

Preceding gene: 113969181

Following gene: 113969184

Centisome position: 21.11

GC content: 57.81

Gene sequence:

>723_bases
ATGAAGCAGCTCAGGTTATTACTGTTACGCCATGGAGAATGCGAGGGCGGGGCGATTTTACGTGGCCGAGTCGATGTGCC
ACTGAGCGACAAGGGCTGGCGGCAGATGTCGGCGGCGGTGGAGGCGCAGGCGACTGTGTGCCACGGCATTTATAGCTCGA
CCTCAAGGCGCTGCGCCGAGTTTGCCAAGGCCTTTGCGGCTGAGCTGCATTCGAGTGCGTCCGTGGGCATGAGTTTAGAT
GCGCCCGCGCCTTTGCCGCTGAAGGTCAACTTGCTGGAGGAGTTACAGGAAATAGCCTTCGGCGATTGGGATGGTTGCCT
GCTCGATGACTTATATCAACGCGACGGCGAGCGGATGGCGGCCTATTGGCAGAATCCCTGGGAGGTGACGCCGCCCAATG
GCGAAGCCATGGCAAGTTTCGAAGCCCGAGTCGATGGGGCGATAGAACAAATCCTCGATAAAGAGTTTGCCCTGCTGGCG
ATGGATGATGAACAGGCCCACGGCGAGTTTAATGCCAATGCACCCGCGGCCAATATCTGGGTAGTGACCCACGGCGGGGT
TATTCGCCATTTGATGTCAAGGGCGCTTGGGGCGGTGAAAACCTTAGGTTTTTACAGTCAGCTCGCCTTACCCGTGGCGG
CGGTGGTGACGATTAATGTCCTCGAGGATGAGCAAGGTAAAAGATACTGGCGTTTAGACTGGCCCTCGGGCCACTGTGAG
TAG

Upstream 100 bases:

>100_bases
AGACGTCCATAATACGCGACATCGGATTGTCAGGGCAAGGCTAAAGTTGGTATAGCATAGGCGAGATAACCCAGATAAAA
ACGATAAAAGGAAAGATCAG

Downstream 100 bases:

>100_bases
CTTAAACGCATCTGCCATCGGTATGATGAAAATTTTCTGATTTAAACAGCATTGCCTAATGAGCAAGATATAGGATAATG
CTTTTCCCTGACGTTTGAGC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKQLRLLLLRHGECEGGAILRGRVDVPLSDKGWRQMSAAVEAQATVCHGIYSSTSRRCAEFAKAFAAELHSSASVGMSLD
APAPLPLKVNLLEELQEIAFGDWDGCLLDDLYQRDGERMAAYWQNPWEVTPPNGEAMASFEARVDGAIEQILDKEFALLA
MDDEQAHGEFNANAPAANIWVVTHGGVIRHLMSRALGAVKTLGFYSQLALPVAAVVTINVLEDEQGKRYWRLDWPSGHCE

Sequences:

>Translated_240_residues
MKQLRLLLLRHGECEGGAILRGRVDVPLSDKGWRQMSAAVEAQATVCHGIYSSTSRRCAEFAKAFAAELHSSASVGMSLD
APAPLPLKVNLLEELQEIAFGDWDGCLLDDLYQRDGERMAAYWQNPWEVTPPNGEAMASFEARVDGAIEQILDKEFALLA
MDDEQAHGEFNANAPAANIWVVTHGGVIRHLMSRALGAVKTLGFYSQLALPVAAVVTINVLEDEQGKRYWRLDWPSGHCE
>Mature_240_residues
MKQLRLLLLRHGECEGGAILRGRVDVPLSDKGWRQMSAAVEAQATVCHGIYSSTSRRCAEFAKAFAAELHSSASVGMSLD
APAPLPLKVNLLEELQEIAFGDWDGCLLDDLYQRDGERMAAYWQNPWEVTPPNGEAMASFEARVDGAIEQILDKEFALLA
MDDEQAHGEFNANAPAANIWVVTHGGVIRHLMSRALGAVKTLGFYSQLALPVAAVVTINVLEDEQGKRYWRLDWPSGHCE

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 26405; Mature: 26405

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLRLLLLRHGECEGGAILRGRVDVPLSDKGWRQMSAAVEAQATVCHGIYSSTSRRCAE
CCHHHEEHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAKAFAAELHSSASVGMSLDAPAPLPLKVNLLEELQEIAFGDWDGCLLDDLYQRDGERMA
HHHHHHHHHHCCCCCCEECCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEE
AYWQNPWEVTPPNGEAMASFEARVDGAIEQILDKEFALLAMDDEQAHGEFNANAPAANIW
HHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEE
VVTHGGVIRHLMSRALGAVKTLGFYSQLALPVAAVVTINVLEDEQGKRYWRLDWPSGHCE
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKQLRLLLLRHGECEGGAILRGRVDVPLSDKGWRQMSAAVEAQATVCHGIYSSTSRRCAE
CCHHHEEHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAKAFAAELHSSASVGMSLDAPAPLPLKVNLLEELQEIAFGDWDGCLLDDLYQRDGERMA
HHHHHHHHHHCCCCCCEECCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEE
AYWQNPWEVTPPNGEAMASFEARVDGAIEQILDKEFALLAMDDEQAHGEFNANAPAANIW
HHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEE
VVTHGGVIRHLMSRALGAVKTLGFYSQLALPVAAVVTINVLEDEQGKRYWRLDWPSGHCE
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]