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The map label for this gene is pbpG [H]

Identifier: 113969172

GI number: 113969172

Start: 972370

End: 973326

Strand: Direct

Name: pbpG [H]

Synonym: Shewmr4_0828

Alternate gene names: 113969172

Gene position: 972370-973326 (Clockwise)

Preceding gene: 113969171

Following gene: 113969173

Centisome position: 20.66

GC content: 47.44

Gene sequence:

>957_bases
ATGAAGATCCCTTCTCTGCTTGGTAGTTTTATCTTGGTATGCAGCAGTTTAACTGTTGCCGCGACAGCGCATTCTGCCGA
TTCGGCCTCTGTCACTACAAAAAGCACCGCCACGGCGAAAAAAGCCCCTGCAAAACAGCAGGAAGTGGCCGCCAATAGTG
CGCTGGTGGTGGATCTAAAAACCAACGAAATTCTCTATTCCAGTAATCCCGATGCCGTAAGGCCTATTGCCTCTGTGACT
AAGCTGATGACCGCCATGGTGACCTTAGATGCTAAGTTGCCTATGGATGAAAAGCTTGCCATCAATATCAATGACACTAA
GGAAATGCGCGGTGTCTACTCTCGAGTGCGTATCGGCAGTGAAATTAGCCGTAAAGATATGTTATTGCTGACATTAATGT
CATCAGAAAACCGTGCTGCAGCGAGTCTTGCCCACCATTATCCCGGTGGTCATAAGGCCTTTATTAAGGCGATGAACGCT
AAGGCAAAAGCCCTAGGTATGAAGAATACTCGTTATGTGGAGCCGACTGGGCTGTCAGAGAAAAACGTTTCGAGTGCCCG
CGATCTGGTGGTGTTACTCAAGGCCAGCGAAGGCTATCCCATGTTAGGTCAGTTAAGCTCGACCGAAAAGAAAACCGTCA
CCTTTGGCAAACCTAAGTACAGCCTCGACTTTAGAAACACTAACCGTTTGGTTTACAAAGATAACTGGAACATTCACCTC
ACTAAAACTGGCTTTACCAATGAAGCAGGCCATTGTTTAGTGATGCGTACCGAAATGGCTAAACGCCAAGTGGCCTTTGT
GGTGCTCGATGCCTATGGTAAATACACCCATATGGCGGATGCTAACCGTTTACGTAACTGGTTAGAAACAGGAAAAGTGA
CTCCTATCCCTGCCGAAGCTAAGCAGTATAAAAAGCAGCGCAGCCAACAGCAGTTTGCCAAAGTCAGCGAGACCTAA

Upstream 100 bases:

>100_bases
GTCGATGGGGATTCTATTCCTTTTTCCACAGACCTCTTATACTTAGCTTCAACCATGTGCGTAGCACATTCGACTTATTT
AACGACTCAGTGAAATCTAC

Downstream 100 bases:

>100_bases
GCAGACATTAATTGCTTATCCATTCAACAAAAAGGCCAGAATCGTTCTGGCCTTTTTGTTGTCATTTTTCTAGCACTTTT
GTTGTAGAGGATTGATTGGC

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKIPSLLGSFILVCSSLTVAATAHSADSASVTTKSTATAKKAPAKQQEVAANSALVVDLKTNEILYSSNPDAVRPIASVT
KLMTAMVTLDAKLPMDEKLAININDTKEMRGVYSRVRIGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKAMNA
KAKALGMKNTRYVEPTGLSEKNVSSARDLVVLLKASEGYPMLGQLSSTEKKTVTFGKPKYSLDFRNTNRLVYKDNWNIHL
TKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHMADANRLRNWLETGKVTPIPAEAKQYKKQRSQQQFAKVSET

Sequences:

>Translated_318_residues
MKIPSLLGSFILVCSSLTVAATAHSADSASVTTKSTATAKKAPAKQQEVAANSALVVDLKTNEILYSSNPDAVRPIASVT
KLMTAMVTLDAKLPMDEKLAININDTKEMRGVYSRVRIGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKAMNA
KAKALGMKNTRYVEPTGLSEKNVSSARDLVVLLKASEGYPMLGQLSSTEKKTVTFGKPKYSLDFRNTNRLVYKDNWNIHL
TKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHMADANRLRNWLETGKVTPIPAEAKQYKKQRSQQQFAKVSET
>Mature_318_residues
MKIPSLLGSFILVCSSLTVAATAHSADSASVTTKSTATAKKAPAKQQEVAANSALVVDLKTNEILYSSNPDAVRPIASVT
KLMTAMVTLDAKLPMDEKLAININDTKEMRGVYSRVRIGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKAMNA
KAKALGMKNTRYVEPTGLSEKNVSSARDLVVLLKASEGYPMLGQLSSTEKKTVTFGKPKYSLDFRNTNRLVYKDNWNIHL
TKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHMADANRLRNWLETGKVTPIPAEAKQYKKQRSQQQFAKVSET

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=258, Percent_Identity=70.9302325581395, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1787062, Length=284, Percent_Identity=28.5211267605634, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87082022, Length=266, Percent_Identity=27.8195488721804, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786851, Length=251, Percent_Identity=25.0996015936255, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 34934; Mature: 34934

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPSLLGSFILVCSSLTVAATAHSADSASVTTKSTATAKKAPAKQQEVAANSALVVDLK
CCCHHHHHHHHHHHCCHHEEEEECCCCCCCEEECCCCHHHCCCCHHHHHHCCCEEEEEEE
TNEILYSSNPDAVRPIASVTKLMTAMVTLDAKLPMDEKLAININDTKEMRGVYSRVRIGS
CCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
EISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKAMNAKAKALGMKNTRYVEPTGLSE
CCCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCCCCC
KNVSSARDLVVLLKASEGYPMLGQLSSTEKKTVTFGKPKYSLDFRNTNRLVYKDNWNIHL
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEECCCEEEE
TKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHMADANRLRNWLETGKVTPIPAEA
EECCCCCCCCCEEEEECHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
KQYKKQRSQQQFAKVSET
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIPSLLGSFILVCSSLTVAATAHSADSASVTTKSTATAKKAPAKQQEVAANSALVVDLK
CCCHHHHHHHHHHHCCHHEEEEECCCCCCCEEECCCCHHHCCCCHHHHHHCCCEEEEEEE
TNEILYSSNPDAVRPIASVTKLMTAMVTLDAKLPMDEKLAININDTKEMRGVYSRVRIGS
CCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
EISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKAMNAKAKALGMKNTRYVEPTGLSE
CCCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCCCCC
KNVSSARDLVVLLKASEGYPMLGQLSSTEKKTVTFGKPKYSLDFRNTNRLVYKDNWNIHL
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEECCCEEEE
TKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHMADANRLRNWLETGKVTPIPAEA
EECCCCCCCCCEEEEECHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
KQYKKQRSQQQFAKVSET
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]