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The map label for this gene is hflX [H]

Identifier: 113968943

GI number: 113968943

Start: 691909

End: 693216

Strand: Direct

Name: hflX [H]

Synonym: Shewmr4_0599

Alternate gene names: 113968943

Gene position: 691909-693216 (Clockwise)

Preceding gene: 113968942

Following gene: 113968944

Centisome position: 14.7

GC content: 47.94

Gene sequence:

>1308_bases
TTGTTTGATCGTTATGAGGCGGGAGAAACAGCGGTTCTTGTCCATATCGACTTTTCCGATGAGGAACGCCGAGAAGACTT
AGTCGAGTTACAGCTATTAGTCGAGTCAGCTGGAGCACGCTCAGTCGGGGTCATTACTGGAAGTCGACGCTCACCAGACC
GTAAGTTTTTTATTGGTTCTGGTAAAGCCGAGGAGTTAGCTGCATTAGTGGCTGCAACTGAGGCTAATGTGGTTATTTTC
AATCACGCCTTGAGTCCTGCTCAAGAGCGAAACCTTGAACAGGTGTGTCAGTGCCGAGTATTGGACCGAACCACGCTGAT
CTTGGATATTTTTGCTCAACGTGCTCGGACCCATGAAGGTAAGTTACAGGTGGAGCTAGCGCAATTGCGCCACATGTCGA
CGCGTCTTGTGCGTGGTTGGACTCACCTTGAGCGCCAAAAAGGCGGTATCGGTTTACGTGGCCCGGGAGAAACCCAGCTC
GAAACCGATAGACGTTTGCTCAGGGGACGCATTAAAAATATCAACAAACGCTTAGAGCGTGTTGATAAACAACGTGAGCA
GAGTCGTCGCGCCCGTAAGCGTAGCGACATGCCAACAGTCTCATTAGTGGGTTATACCAACGCGGGCAAGTCAACGCTGT
TTAATGCCTTAACCTCATCTGATGTTTATGCAGCCGACCAGCTATTTGCCACACTCGATCCCACATTGAGAAAGTTAGAT
CTACCCGATGGTGCCGTGATCTTGGCGGACACTGTAGGTTTTATTCGCCATTTACCACACGATCTAGTTGCCGCTTTTAA
GGCAACATTGCAAGAAACGCGTCAAGCGGATTTGTTGCTGCATATTGTTGATTGTGCTGATGAGAACATGGCGGATAACT
TCGAGCAGGTACAAAACGTGCTCGAAGATATCGATGCTGCTGGGGTGATGCAGTTGGTTGTTTGTAATAAAATCGACCTG
CTTGAGGATGTCACACCGCGCATCGAATATGATGAACACAGTAAGCCCGTACGTGTCTGGGTTTCGGCACAAAAGCGTTT
GGGATTTGATCTACTCTTGAAGGCGATCACCGAATTAATCGGTGAAGTGATTCATGAGCTTACACTTAAGATTCCAGCAA
CTGCTGGACATTATCTTGGCCAGTTTTATCGACTGGATGCGATACAGCAGAAAGAGTACGACGATCTGGGGAACTGTATT
TTGTCTGTTCGTTTATCGGATGCCGATTGGCGCCGATTAGCTAAACAGAGTCAGGGTGAGTTAGAAACCTTTATCTTCGA
TCCGTCGATAGAAAAGGCTGTTTGTTAA

Upstream 100 bases:

>100_bases
TCCATTTAACGTTGCTGGCCATCAAAATGCCCAGGGCGGTTATGGTGCGCAAGACGATATGCCAAGTGGCGAATAAGTTT
TAGTTTGAGGAGTTTGCTTC

Downstream 100 bases:

>100_bases
TAATCTAATTTATTTCATCCACTTATGGAGTGCTAAATGGCTTGGAACGAGCCCGGTAACAAGGGTAATGATCCTTGGGG
AAATAAAGGTGGTAACGACA

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGSGKAEELAALVAATEANVVIF
NHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINKRLERVDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNVLEDIDAAGVMQLVVCNKIDL
LEDVTPRIEYDEHSKPVRVWVSAQKRLGFDLLLKAITELIGEVIHELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLSDADWRRLAKQSQGELETFIFDPSIEKAVC

Sequences:

>Translated_435_residues
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGSGKAEELAALVAATEANVVIF
NHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINKRLERVDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNVLEDIDAAGVMQLVVCNKIDL
LEDVTPRIEYDEHSKPVRVWVSAQKRLGFDLLLKAITELIGEVIHELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLSDADWRRLAKQSQGELETFIFDPSIEKAVC
>Mature_435_residues
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGSGKAEELAALVAATEANVVIF
NHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINKRLERVDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNVLEDIDAAGVMQLVVCNKIDL
LEDVTPRIEYDEHSKPVRVWVSAQKRLGFDLLLKAITELIGEVIHELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLSDADWRRLAKQSQGELETFIFDPSIEKAVC

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=266, Percent_Identity=34.2105263157895, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310133116, Length=264, Percent_Identity=34.469696969697, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310124269, Length=246, Percent_Identity=34.9593495934959, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI310124267, Length=246, Percent_Identity=34.9593495934959, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI310124171, Length=246, Percent_Identity=34.9593495934959, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI310124169, Length=246, Percent_Identity=34.9593495934959, Blast_Score=118, Evalue=9e-27,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=64.0845070422535, Blast_Score=550, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17561038, Length=277, Percent_Identity=32.4909747292419, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24650079, Length=363, Percent_Identity=31.129476584022, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48989; Mature: 48989

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGS
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECC
GKAEELAALVAATEANVVIFNHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEG
CCHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIKNINKRLER
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHCC
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNV
CCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHHH
LEDIDAAGVMQLVVCNKIDLLEDVTPRIEYDEHSKPVRVWVSAQKRLGFDLLLKAITELI
HHHHCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHH
GEVIHELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCILSVRLSDADWRRLAKQSQGE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCC
LETFIFDPSIEKAVC
EEEEEECCCHHHHCC
>Mature Secondary Structure
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGS
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECC
GKAEELAALVAATEANVVIFNHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEG
CCHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIKNINKRLER
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHCC
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNV
CCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHHH
LEDIDAAGVMQLVVCNKIDLLEDVTPRIEYDEHSKPVRVWVSAQKRLGFDLLLKAITELI
HHHHCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHH
GEVIHELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCILSVRLSDADWRRLAKQSQGE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCC
LETFIFDPSIEKAVC
EEEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]