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The map label for this gene is exeF [H]

Identifier: 113968503

GI number: 113968503

Start: 181359

End: 182582

Strand: Direct

Name: exeF [H]

Synonym: Shewmr4_0158

Alternate gene names: 113968503

Gene position: 181359-182582 (Clockwise)

Preceding gene: 113968502

Following gene: 113968504

Centisome position: 3.85

GC content: 52.29

Gene sequence:

>1224_bases
ATGCCAGCATTTGAATATAAGGCGCTGGACGCCAAGGGAAAACAGCTAAAAGGGGTGATTGAGGCGGATACCGCCAGACA
TGCTCGTAGTCAGCTGCGTGACCAACGCATGATGCCGCTGGAGATTTTGCCGGTCACCGAAAAGGAAGCCAAGGCAAAAG
GCACCGGATTCTCGCCCTTTAAACGCGGGATTTCGGTGGCGGAATTAGCGTTGATCACCCGTCAAATCGCCACACTGGTC
GCGGCGGGCTTACCGATTGAGGAATGTCTCAAGGCGGTGGGTCAGCAATGTGAGAAGGCGCGCCTAGCCAGTATGATCAT
GGCGGTGCGCTCCCGCGTGGTGGAAGGCTATAGTCTGGCCGACTCTCTTGCCGAGTTTCCGCATATTTTCGATGACTTAT
ACCGAGCTATGGTGGCCTCGGGTGAAAAATCCGGTCACTTGGAAGTGGTGCTTAACCGCTTAGCCGATTACACCGAGCGC
CGCCAGCAGCTGAAGTCCAAACTGCAACAGGCGATGATTTACCCCATTATGCTGACCATTGTTGCCATTGGTGTAGTGTC
AGTGTTGCTGGCGGCTGTGGTACCAAAGGTGGTGGGGCAATTTGAACATATGGGCGCCGAGTTACCCGCAACGACCCGTT
TCTTAATTGCCGCCTCTGACTTTGTGCAAAGCTATGGCCTACTCGTGGTATTGATTATTGGTATTTTGCTGGTGGTGTTT
CAGCGTTTACTTAAGTCACCGATTTTCAAGATGAAATACCATACGTTTTTGCTGAAAATGCCAGTGGTTGGCCGTGTGAG
TAAAGGGCTTAATACCGCGCGATTTGCGCGAACTCTGAGTATTTTATCTGCCAGTTCGGTGCCTTTGTTAGATGGGATGC
GCATTGCCAGCGAAGTATTGCAAAATGTGCGGGTGCGGGCGGCGGTAGATGATGCTACGGCGCGCGTACGGGAAGGAACT
AGCCTAAGCACTGCGTTGACTAACACTAAGCTGTTCCCGGCGATGATGTTATATATGATCGCCTCGGGGGAGAAGAGTGG
TCAGCTCGAAGACATGCTTGAGCGCGCAGCTGATAACCAGGATAGGGAATTCGAGAGTAATGTTACACTTGCCCTCGGGG
TTTTCGAGCCGGCATTGGTGGTGAGCATGGCGGGGGTTGTACTCTTTATCGTGATGGCCATTCTGCAACCTATCTTGGCA
CTGAACAATTTGATTAGTGGCTAG

Upstream 100 bases:

>100_bases
CCAGTCGGTGCCAAGCATTCGCCACGATGGCATGAGCAAGGTGCTCTCAGGTATCACCACTCTGGAAGAAGTCCTGAGGG
TGACCCGCGAGGAGTAAGCT

Downstream 100 bases:

>100_bases
TTTTTTAATTTATGGATTATTGCCTTGCAGTGTTCAAACTGAGAATGGCACAGGTTTTTTTAGGAGAAGTAGTCGATGCA
AATGAACAAAAAGCACAAGG

Product: general secretion pathway protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MPAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVTEKEAKAKGTGFSPFKRGISVAELALITRQIATLV
AAGLPIEECLKAVGQQCEKARLASMIMAVRSRVVEGYSLADSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTER
RQQLKSKLQQAMIYPIMLTIVAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQSYGLLVVLIIGILLVVF
QRLLKSPIFKMKYHTFLLKMPVVGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEVLQNVRVRAAVDDATARVREGT
SLSTALTNTKLFPAMMLYMIASGEKSGQLEDMLERAADNQDREFESNVTLALGVFEPALVVSMAGVVLFIVMAILQPILA
LNNLISG

Sequences:

>Translated_407_residues
MPAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVTEKEAKAKGTGFSPFKRGISVAELALITRQIATLV
AAGLPIEECLKAVGQQCEKARLASMIMAVRSRVVEGYSLADSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTER
RQQLKSKLQQAMIYPIMLTIVAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQSYGLLVVLIIGILLVVF
QRLLKSPIFKMKYHTFLLKMPVVGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEVLQNVRVRAAVDDATARVREGT
SLSTALTNTKLFPAMMLYMIASGEKSGQLEDMLERAADNQDREFESNVTLALGVFEPALVVSMAGVVLFIVMAILQPILA
LNNLISG
>Mature_406_residues
PAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVTEKEAKAKGTGFSPFKRGISVAELALITRQIATLVA
AGLPIEECLKAVGQQCEKARLASMIMAVRSRVVEGYSLADSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERR
QQLKSKLQQAMIYPIMLTIVAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQSYGLLVVLIIGILLVVFQ
RLLKSPIFKMKYHTFLLKMPVVGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEVLQNVRVRAAVDDATARVREGTS
LSTALTNTKLFPAMMLYMIASGEKSGQLEDMLERAADNQDREFESNVTLALGVFEPALVVSMAGVVLFIVMAILQPILAL
NNLISG

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=46.4019851116625, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1786295, Length=405, Percent_Identity=24.6913580246914, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR011850
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44417; Mature: 44286

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVTEKEAKAKGTGFSPF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCCHH
KRGISVAELALITRQIATLVAAGLPIEECLKAVGQQCEKARLASMIMAVRSRVVEGYSLA
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKLQQAMIYPIMLTI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQSYGLLVVLIIGILLVVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLLKSPIFKMKYHTFLLKMPVVGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEVL
HHHHHCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QNVRVRAAVDDATARVREGTSLSTALTNTKLFPAMMLYMIASGEKSGQLEDMLERAADNQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
DREFESNVTLALGVFEPALVVSMAGVVLFIVMAILQPILALNNLISG
CCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVTEKEAKAKGTGFSPF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCCHH
KRGISVAELALITRQIATLVAAGLPIEECLKAVGQQCEKARLASMIMAVRSRVVEGYSLA
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKLQQAMIYPIMLTI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQSYGLLVVLIIGILLVVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLLKSPIFKMKYHTFLLKMPVVGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEVL
HHHHHCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QNVRVRAAVDDATARVREGTSLSTALTNTKLFPAMMLYMIASGEKSGQLEDMLERAADNQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
DREFESNVTLALGVFEPALVVSMAGVVLFIVMAILQPILALNNLISG
CCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1640836 [H]