Click here to switch to the map view.

The map label for this gene is pdhB [H]

Identifier: 113478393

GI number: 113478393

Start: 7748596

End: 7749579

Strand: Reverse

Name: pdhB [H]

Synonym: Tery_5078

Alternate gene names: 113478393

Gene position: 7749579-7748596 (Counterclockwise)

Preceding gene: NA

Following gene: 113478392

Centisome position: 99.99

GC content: 38.01

Gene sequence:

>984_bases
ATGGCACAAACTTTATTATTTAATGCTCTCCGTGCAGCTATTGATGAAGAGATGGCTCACGACCCAACTGTATATGTTCT
TGGTGAAGACGTAGGTCACTATGGAGGCTCCTACAAAGTGACCAAAGGTCTTTATGAAAAATATGGGGAACTACGTATTC
TTGATACTCCTATTGCAGAAAATAGCTTTACAGGAATGGCTATAGGTTCAGCCCTGACTGGACTACGGCCTATCATTGAA
GGCATGAATATGGGATTTTTATTATTGGCCTTTAACCAAATTGCCAATAATGCTGGAATGTTACGCTATACCTCTGGTGG
TAATTTCAAAATTCCATTAGTGATTCGTGGCCCTGGTGGTGTGGGTCGTCAGTTAGGTGCAGAGCATTCCCAAAGATTAG
AAGCCTATTTTCAAGCTGTTCCTGGTCTTAAAATAGTAGCTTGTTCAACTCCATACAACGCCAAAGGTTTACTTAAATCA
GCTATCCGTGATGAAAATCCGGTCTTATTTTTTGAGCATGTCCTTCTTTATAATCTCAAAGAAGACTTGCCAGAAGATGA
GTATTTGTTACCTCTAGATAAAGCAGAAGTGGTACAAACTGGAAAAGATGTTACTATCTTGACCTATTCGAGAATGCGTC
ATCACGTTACCCAAGCAGTACAAACTTTGAAAAAACAGGGTTATGACCCGGAGGTAATAGACCTCATATCTCTCAAACCT
TTAGATTTTGAAACTATTGGTGCTTCTATTAAGAAAACTCACCGGGTGATTATTGTTGAAGAGTGTATGAAAACAGGTGG
TATTGCTGCTGAGTTAATTGCCTCAATTAATGAAAAATTATTTGATGAACTAGATGCTCCTATTTTACGATTGTCTTCTC
AAGACATTCCTACACCTTATAATGGTTTACTTGAAAGATTAACAATTGTACAACCAGAGCAAATTGTTGAAGCAGTACAA
AAAATGGTGGCAATTAAAGTTTAA

Upstream 100 bases:

>100_bases
ATATATATAAAACAATTAGGTGAACTCACCCTAGAAGTCTATATCTGATTCTCAAGTCAGAGTGGAAATTGTTACCTAAC
TCACATAACCAACCTGTTAA

Downstream 100 bases:

>100_bases
CTGGAAGCAAGAAGGAGGAAGACTTTAGTTATCTAGGAGAGAAAGAAGAAGCAAGAAGACTAATTAAATTTTTTGATAAC
ATAAACGATTCAAGCTTTGT

Product: transketolase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAQTLLFNALRAAIDEEMAHDPTVYVLGEDVGHYGGSYKVTKGLYEKYGELRILDTPIAENSFTGMAIGSALTGLRPIIE
GMNMGFLLLAFNQIANNAGMLRYTSGGNFKIPLVIRGPGGVGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKS
AIRDENPVLFFEHVLLYNLKEDLPEDEYLLPLDKAEVVQTGKDVTILTYSRMRHHVTQAVQTLKKQGYDPEVIDLISLKP
LDFETIGASIKKTHRVIIVEECMKTGGIAAELIASINEKLFDELDAPILRLSSQDIPTPYNGLLERLTIVQPEQIVEAVQ
KMVAIKV

Sequences:

>Translated_327_residues
MAQTLLFNALRAAIDEEMAHDPTVYVLGEDVGHYGGSYKVTKGLYEKYGELRILDTPIAENSFTGMAIGSALTGLRPIIE
GMNMGFLLLAFNQIANNAGMLRYTSGGNFKIPLVIRGPGGVGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKS
AIRDENPVLFFEHVLLYNLKEDLPEDEYLLPLDKAEVVQTGKDVTILTYSRMRHHVTQAVQTLKKQGYDPEVIDLISLKP
LDFETIGASIKKTHRVIIVEECMKTGGIAAELIASINEKLFDELDAPILRLSSQDIPTPYNGLLERLTIVQPEQIVEAVQ
KMVAIKV
>Mature_326_residues
AQTLLFNALRAAIDEEMAHDPTVYVLGEDVGHYGGSYKVTKGLYEKYGELRILDTPIAENSFTGMAIGSALTGLRPIIEG
MNMGFLLLAFNQIANNAGMLRYTSGGNFKIPLVIRGPGGVGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKSA
IRDENPVLFFEHVLLYNLKEDLPEDEYLLPLDKAEVVQTGKDVTILTYSRMRHHVTQAVQTLKKQGYDPEVIDLISLKPL
DFETIGASIKKTHRVIIVEECMKTGGIAAELIASINEKLFDELDAPILRLSSQDIPTPYNGLLERLTIVQPEQIVEAVQK
MVAIKV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156564403, Length=328, Percent_Identity=40.5487804878049, Blast_Score=271, Evalue=8e-73,
Organism=Homo sapiens, GI291084858, Length=328, Percent_Identity=38.4146341463415, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI4557353, Length=322, Percent_Identity=39.4409937888199, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI34101272, Length=322, Percent_Identity=39.4409937888199, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17538422, Length=323, Percent_Identity=42.1052631578947, Blast_Score=280, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI17506935, Length=321, Percent_Identity=34.8909657320872, Blast_Score=177, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6319698, Length=324, Percent_Identity=42.2839506172839, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI21358145, Length=330, Percent_Identity=40.9090909090909, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24650940, Length=330, Percent_Identity=40.9090909090909, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI160714832, Length=321, Percent_Identity=37.3831775700935, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI160714828, Length=321, Percent_Identity=37.3831775700935, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24650943, Length=90, Percent_Identity=46.6666666666667, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24650945, Length=90, Percent_Identity=46.6666666666667, Blast_Score=104, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000089
- InterPro:   IPR011053
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 36056; Mature: 35925

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTLLFNALRAAIDEEMAHDPTVYVLGEDVGHYGGSYKVTKGLYEKYGELRILDTPIAE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCC
NSFTGMAIGSALTGLRPIIEGMNMGFLLLAFNQIANNAGMLRYTSGGNFKIPLVIRGPGG
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCC
VGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKSAIRDENPVLFFEHVLLYNLK
CCHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHH
EDLPEDEYLLPLDKAEVVQTGKDVTILTYSRMRHHVTQAVQTLKKQGYDPEVIDLISLKP
HHCCCCCEEECCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCC
LDFETIGASIKKTHRVIIVEECMKTGGIAAELIASINEKLFDELDAPILRLSSQDIPTPY
CCHHHHHHHHHHHHEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCH
NGLLERLTIVQPEQIVEAVQKMVAIKV
HHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQTLLFNALRAAIDEEMAHDPTVYVLGEDVGHYGGSYKVTKGLYEKYGELRILDTPIAE
CHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCC
NSFTGMAIGSALTGLRPIIEGMNMGFLLLAFNQIANNAGMLRYTSGGNFKIPLVIRGPGG
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCC
VGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKSAIRDENPVLFFEHVLLYNLK
CCHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHH
EDLPEDEYLLPLDKAEVVQTGKDVTILTYSRMRHHVTQAVQTLKKQGYDPEVIDLISLKP
HHCCCCCEEECCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCC
LDFETIGASIKKTHRVIIVEECMKTGGIAAELIASINEKLFDELDAPILRLSSQDIPTPY
CCHHHHHHHHHHHHEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCH
NGLLERLTIVQPEQIVEAVQKMVAIKV
HHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515924 [H]