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The map label for this gene is ahpC [C]

Identifier: 113478360

GI number: 113478360

Start: 7698675

End: 7699313

Strand: Reverse

Name: ahpC [C]

Synonym: Tery_5038

Alternate gene names: 113478360

Gene position: 7699313-7698675 (Counterclockwise)

Preceding gene: 113478361

Following gene: 113478358

Centisome position: 99.34

GC content: 38.18

Gene sequence:

>639_bases
ATGACTTTAAGACTAGGTGACAAAGTACCTGACTTTACTCAAGATTCCTCCGAAGGACAAATTAGCTTTTACGACTGGGC
AGGCGATAGTTGGGTAGTGCTTTTTTCTCACCCTGCTGACTTTACTCCAGTTTGCACAACAGAATTAGGGGCAGTTGCCA
GACTAAAACCAGAATTTGACAAGCGTGGAGTCAAAGTCATTGCCCTAAGTGTAGATGACGCAGAATCTCATAAAGGCTGG
GTTGGAGACATCAATGAAACTCAAAAAACAACTGTTAATTACCCTATTTTAGCAGATGTAGATAAAAAGGTTTCTGACCT
ATACGATATGATTCATCCGAACTCTTTAAATAACCTAACAATTCGTAGTGTTTTTATTATCGACTCTGAAAAGAAACTTC
GTCTTACTTTTACTTATCCAGCAAGTACAGGTCGTAACTTTAATGAAATTCTCAGGGTAATTGACTCTTTACAACTAACG
GATAATCATCAAGTTGCTACTCCTGTAGATTGGAAAGATGGAGATGATTGTGTAATTGTTCCTTCTCTAAAAGACCCCGA
AGTATTGAAAGAAAAATTCCCCAAGGGCTACACAGAAGTTAAGCCATATTTGCGAATGACTCCTCAACCTAATAAGTAA

Upstream 100 bases:

>100_bases
TAATCTTAATTTTTAAGAATATCTAAAGTTAAAAGCTTAAATCCTTAAAAAATGAAACTATATAGAATTGCTAATTCTAA
ACAAGATAGGACATTCGGCT

Downstream 100 bases:

>100_bases
ATCAATAAATAAATAAATACATTGAATTAAGGATTAATAGTTTGACTAAAATTATCAATTCTTAATTTTTTTTAAGAGGA
ACATAAGCTAGAAAAACTGA

Product: 1-Cys peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTLRLGDKVPDFTQDSSEGQISFYDWAGDSWVVLFSHPADFTPVCTTELGAVARLKPEFDKRGVKVIALSVDDAESHKGW
VGDINETQKTTVNYPILADVDKKVSDLYDMIHPNSLNNLTIRSVFIIDSEKKLRLTFTYPASTGRNFNEILRVIDSLQLT
DNHQVATPVDWKDGDDCVIVPSLKDPEVLKEKFPKGYTEVKPYLRMTPQPNK

Sequences:

>Translated_212_residues
MTLRLGDKVPDFTQDSSEGQISFYDWAGDSWVVLFSHPADFTPVCTTELGAVARLKPEFDKRGVKVIALSVDDAESHKGW
VGDINETQKTTVNYPILADVDKKVSDLYDMIHPNSLNNLTIRSVFIIDSEKKLRLTFTYPASTGRNFNEILRVIDSLQLT
DNHQVATPVDWKDGDDCVIVPSLKDPEVLKEKFPKGYTEVKPYLRMTPQPNK
>Mature_211_residues
TLRLGDKVPDFTQDSSEGQISFYDWAGDSWVVLFSHPADFTPVCTTELGAVARLKPEFDKRGVKVIALSVDDAESHKGWV
GDINETQKTTVNYPILADVDKKVSDLYDMIHPNSLNNLTIRSVFIIDSEKKLRLTFTYPASTGRNFNEILRVIDSLQLTD
NHQVATPVDWKDGDDCVIVPSLKDPEVLKEKFPKGYTEVKPYLRMTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=49.7737556561086, Blast_Score=209, Evalue=1e-54,
Organism=Homo sapiens, GI32189392, Length=197, Percent_Identity=34.010152284264, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI4505591, Length=198, Percent_Identity=32.3232323232323, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI32455266, Length=198, Percent_Identity=32.3232323232323, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI32455264, Length=198, Percent_Identity=32.3232323232323, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI5453549, Length=166, Percent_Identity=30.7228915662651, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=32.9608938547486, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5802974, Length=179, Percent_Identity=32.9608938547486, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=31.8181818181818, Blast_Score=78, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=200, Percent_Identity=41.5, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17554494, Length=154, Percent_Identity=35.0649350649351, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI32565831, Length=191, Percent_Identity=32.4607329842932, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193204376, Length=191, Percent_Identity=32.4607329842932, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=53.7735849056604, Blast_Score=232, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=170, Percent_Identity=31.1764705882353, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=54.7945205479452, Blast_Score=239, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=49.0291262135922, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=48.5436893203884, Blast_Score=183, Evalue=7e-47,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=48.5436893203884, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=31.8681318681319, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17738015, Length=196, Percent_Identity=30.6122448979592, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17157991, Length=177, Percent_Identity=32.7683615819209, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641739, Length=177, Percent_Identity=32.7683615819209, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24656348, Length=177, Percent_Identity=33.8983050847458, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864676, Length=177, Percent_Identity=33.8983050847458, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23933; Mature: 23802

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLGDKVPDFTQDSSEGQISFYDWAGDSWVVLFSHPADFTPVCTTELGAVARLKPEFD
CEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHCCCEECCCCCC
KRGVKVIALSVDDAESHKGWVGDINETQKTTVNYPILADVDKKVSDLYDMIHPNSLNNLT
CCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCCCCCEE
IRSVFIIDSEKKLRLTFTYPASTGRNFNEILRVIDSLQLTDNHQVATPVDWKDGDDCVIV
EEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCCEECCCCCCCCCCEEEE
PSLKDPEVLKEKFPKGYTEVKPYLRMTPQPNK
CCCCCHHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
TLRLGDKVPDFTQDSSEGQISFYDWAGDSWVVLFSHPADFTPVCTTELGAVARLKPEFD
EEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHCCCEECCCCCC
KRGVKVIALSVDDAESHKGWVGDINETQKTTVNYPILADVDKKVSDLYDMIHPNSLNNLT
CCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCCCCCEE
IRSVFIIDSEKKLRLTFTYPASTGRNFNEILRVIDSLQLTDNHQVATPVDWKDGDDCVIV
EEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCCEECCCCCCCCCCEEEE
PSLKDPEVLKEKFPKGYTEVKPYLRMTPQPNK
CCCCCHHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]