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The map label for this gene is yycF [H]

Identifier: 113478264

GI number: 113478264

Start: 7519815

End: 7520588

Strand: Reverse

Name: yycF [H]

Synonym: Tery_4937

Alternate gene names: 113478264

Gene position: 7520588-7519815 (Counterclockwise)

Preceding gene: 113478266

Following gene: 113478263

Centisome position: 97.04

GC content: 41.21

Gene sequence:

>774_bases
ATGCCCCGAATACTCGTCATTGATGATGATCCTGCGATCGCAGAACTCGTTGCCGTAAACTTAGAAATGGCTGGCTATGA
AGTTAGTCAAGCAGAAGATGGTATAAAAGGACAAGCTCTAGCTTTGCAACTATTACCAGACCTGATAGTGTTAGATTTAA
TGCTGCCGAAAGTAGATGGGTTTACAGTATGTCAACGTCTGCGTCGTGATGAACGAACAGCGGATATTCCAGTGTTGATG
TTAACTGCTTTGGGTCAAACCCAAGATAAAGTAGAAGGTTTTAATGCTGGTGCAGATGATTATTTAACAAAACCCTTTGA
AATAGAAGAAATGCTGGCACGAGTCCGTGCTTTACTGCGACGCACAGATCGAATTCCTCAAGCAGCTAAACATAGTGAAA
TACTAAGTTATGGCCCTTTGACCCTGGTTCCCGAAAGGTTTGAGGCTATCTGGTTTGATCAAACAGTTAAATTAACTCAT
CTGGAATTTGAGTTACTCCATTGTTTACTACAACGCCATGGCCAGACAGTATCTCCTAGTGAAATTCTTAAGGAAGTCTG
GGGTTACGATCCAGACGATGATATTGAGACAATTCGAGTCCATATTAGACATCTCAGAACTAAAATGGAACCAGATCCTC
GTCATCCTCGGTATATTAAAACCGTATATGGTGCTGGCTATTGCTTAGAATTACCTAGTAATGGGTCCAGTACTAATAAT
GAGGAAACAGCTAATTGGTCTCAACCAAATAGGGATATGGTTAGAGAACCTTAG

Upstream 100 bases:

>100_bases
GTAATGTTTTGAAGGAAAAATCTCACATTTAATGGAAAAGCTTAAAAATCTTAATTAAACATTACAATAAGAAAAAATCG
TAGGTTAAGTGTAGGAAATG

Downstream 100 bases:

>100_bases
GATAATTTCCGGTTGAAAAGTCATAATTAGACAGATAAAATCAAGCTAAAGAGATATTGGTTAATATCCTACAAAATTTA
TAATTATGATCTCTCAACCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPRILVIDDDPAIAELVAVNLEMAGYEVSQAEDGIKGQALALQLLPDLIVLDLMLPKVDGFTVCQRLRRDERTADIPVLM
LTALGQTQDKVEGFNAGADDYLTKPFEIEEMLARVRALLRRTDRIPQAAKHSEILSYGPLTLVPERFEAIWFDQTVKLTH
LEFELLHCLLQRHGQTVSPSEILKEVWGYDPDDDIETIRVHIRHLRTKMEPDPRHPRYIKTVYGAGYCLELPSNGSSTNN
EETANWSQPNRDMVREP

Sequences:

>Translated_257_residues
MPRILVIDDDPAIAELVAVNLEMAGYEVSQAEDGIKGQALALQLLPDLIVLDLMLPKVDGFTVCQRLRRDERTADIPVLM
LTALGQTQDKVEGFNAGADDYLTKPFEIEEMLARVRALLRRTDRIPQAAKHSEILSYGPLTLVPERFEAIWFDQTVKLTH
LEFELLHCLLQRHGQTVSPSEILKEVWGYDPDDDIETIRVHIRHLRTKMEPDPRHPRYIKTVYGAGYCLELPSNGSSTNN
EETANWSQPNRDMVREP
>Mature_256_residues
PRILVIDDDPAIAELVAVNLEMAGYEVSQAEDGIKGQALALQLLPDLIVLDLMLPKVDGFTVCQRLRRDERTADIPVLML
TALGQTQDKVEGFNAGADDYLTKPFEIEEMLARVRALLRRTDRIPQAAKHSEILSYGPLTLVPERFEAIWFDQTVKLTHL
EFELLHCLLQRHGQTVSPSEILKEVWGYDPDDDIETIRVHIRHLRTKMEPDPRHPRYIKTVYGAGYCLELPSNGSSTNNE
ETANWSQPNRDMVREP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=38.2222222222222, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786784, Length=235, Percent_Identity=37.0212765957447, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=37.8854625550661, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=35.8078602620087, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=37.0044052863436, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=34.7639484978541, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=241, Percent_Identity=35.2697095435685, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=39.3162393162393, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.3612334801762, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=33.1858407079646, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=34.6320346320346, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=29.1304347826087, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=29.6137339055794, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=30.9090909090909, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29238; Mature: 29107

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRILVIDDDPAIAELVAVNLEMAGYEVSQAEDGIKGQALALQLLPDLIVLDLMLPKVDG
CCEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
FTVCQRLRRDERTADIPVLMLTALGQTQDKVEGFNAGADDYLTKPFEIEEMLARVRALLR
HHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHH
RTDRIPQAAKHSEILSYGPLTLVPERFEAIWFDQTVKLTHLEFELLHCLLQRHGQTVSPS
HHHCCCCHHHHHHHHHCCCCEECHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCHH
EILKEVWGYDPDDDIETIRVHIRHLRTKMEPDPRHPRYIKTVYGAGYCLELPSNGSSTNN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCC
EETANWSQPNRDMVREP
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRILVIDDDPAIAELVAVNLEMAGYEVSQAEDGIKGQALALQLLPDLIVLDLMLPKVDG
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
FTVCQRLRRDERTADIPVLMLTALGQTQDKVEGFNAGADDYLTKPFEIEEMLARVRALLR
HHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHH
RTDRIPQAAKHSEILSYGPLTLVPERFEAIWFDQTVKLTHLEFELLHCLLQRHGQTVSPS
HHHCCCCHHHHHHHHHCCCCEECHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCHH
EILKEVWGYDPDDDIETIRVHIRHLRTKMEPDPRHPRYIKTVYGAGYCLELPSNGSSTNN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCC
EETANWSQPNRDMVREP
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]