Click here to switch to the map view.

The map label for this gene is yciC [H]

Identifier: 113478002

GI number: 113478002

Start: 7096147

End: 7097130

Strand: Reverse

Name: yciC [H]

Synonym: Tery_4617

Alternate gene names: 113478002

Gene position: 7097130-7096147 (Counterclockwise)

Preceding gene: 113478003

Following gene: 113478001

Centisome position: 91.57

GC content: 30.39

Gene sequence:

>984_bases
ATGAATAATTCACTAGAATTAAATATTCCTAAAAGAGGGATGCCAGTTACTATTATTACCGGATTTTTAGGTAGTGGTAA
AACAACCCTGATAAATCAAATTTTGCAGAATAAGCAGGATTTAAAAGTCGCAGTATTAGTTAATGAATTTGGGGATCTTA
ATATAGATACCCAGTTATTAACAGATATGAACGATAATATGATAGAACTTAGTAATGGTTGTATTTGTTGTACTATCAAT
GAAGGATTAGTAGATGCAGTATATCAAGTTTTAGAAAGCGATAAAAAAATAGATTATTTAATTATAGAAACTACTGGTGT
AGCAGATCCTTTGCCAATTATTTTAACTTTTTTGAGTACAGATTTAAAAGATTTAACTCACTTAGATTCTGTACTGACTT
TAGTGGATTGTGAAAATTTTACACCAGACCATTTCGATAGTGAAGCAGCTTTTAAACAGATTGCTTATGGGGATATTATT
ATACTCAATAAAATAGATTTAGCCTCCCAAGATAAAGTAGATTATTTAGACTCTTATATTAAAACTATAAGAAGTGGAGC
TAGGATTTTAAGAAGTGAGCACAGTAATATACCATCATACTTAATTTTAGATGTAAATATATCAAGGCTTCAGCCTTATT
CTCTAGAGGACAATAACGATCACTCAAAACTACAAAAAAATCCTAAAGATCATCTGATAAATGATGGTTTTATGTCTGTT
TCATTCCAAAGTACAAGACCTTTTTCTGCCCTGAAATTCCAACATAATTTTATAGAGGAATTGCCAGATAATGTATTTAG
AGCCAAAGGAATTCTTTGGTTCCAAGAAAGTGAATCAAAACATATATTTCAATTGAGTGGTAAGCGCTATGAGATGGAAA
TAGATGAATGGTCAACCACTCCGACAAATCAGCTAGTATTAATTGGGCGAAATTTGGATCCATTAATAATTCAACAAAAC
TTAACAAATTGTCTAACTATGTGA

Upstream 100 bases:

>100_bases
GTTTTCTTGTTAGTGACAAAACCACCTTACTCAATCGTATTATTCATGATAAACAAGGTTTTTGTTTGAGTAGCTACCCT
CGTAAATAAATTTAGCAGTA

Downstream 100 bases:

>100_bases
TAAATTAATATTGGCTATTCATAAACACAGATAATAGTCCTTATAGTTCATCTAAACTTTATGAGGGAAAATATCTGTCA
AACCGTTCAACAAAACATTA

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNNSLELNIPKRGMPVTIITGFLGSGKTTLINQILQNKQDLKVAVLVNEFGDLNIDTQLLTDMNDNMIELSNGCICCTIN
EGLVDAVYQVLESDKKIDYLIIETTGVADPLPIILTFLSTDLKDLTHLDSVLTLVDCENFTPDHFDSEAAFKQIAYGDII
ILNKIDLASQDKVDYLDSYIKTIRSGARILRSEHSNIPSYLILDVNISRLQPYSLEDNNDHSKLQKNPKDHLINDGFMSV
SFQSTRPFSALKFQHNFIEELPDNVFRAKGILWFQESESKHIFQLSGKRYEMEIDEWSTTPTNQLVLIGRNLDPLIIQQN
LTNCLTM

Sequences:

>Translated_327_residues
MNNSLELNIPKRGMPVTIITGFLGSGKTTLINQILQNKQDLKVAVLVNEFGDLNIDTQLLTDMNDNMIELSNGCICCTIN
EGLVDAVYQVLESDKKIDYLIIETTGVADPLPIILTFLSTDLKDLTHLDSVLTLVDCENFTPDHFDSEAAFKQIAYGDII
ILNKIDLASQDKVDYLDSYIKTIRSGARILRSEHSNIPSYLILDVNISRLQPYSLEDNNDHSKLQKNPKDHLINDGFMSV
SFQSTRPFSALKFQHNFIEELPDNVFRAKGILWFQESESKHIFQLSGKRYEMEIDEWSTTPTNQLVLIGRNLDPLIIQQN
LTNCLTM
>Mature_327_residues
MNNSLELNIPKRGMPVTIITGFLGSGKTTLINQILQNKQDLKVAVLVNEFGDLNIDTQLLTDMNDNMIELSNGCICCTIN
EGLVDAVYQVLESDKKIDYLIIETTGVADPLPIILTFLSTDLKDLTHLDSVLTLVDCENFTPDHFDSEAAFKQIAYGDII
ILNKIDLASQDKVDYLDSYIKTIRSGARILRSEHSNIPSYLILDVNISRLQPYSLEDNNDHSKLQKNPKDHLINDGFMSV
SFQSTRPFSALKFQHNFIEELPDNVFRAKGILWFQESESKHIFQLSGKRYEMEIDEWSTTPTNQLVLIGRNLDPLIIQQN
LTNCLTM

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=339, Percent_Identity=32.7433628318584, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI33469141, Length=339, Percent_Identity=32.7433628318584, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI148727351, Length=339, Percent_Identity=32.7433628318584, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI223941779, Length=336, Percent_Identity=30.6547619047619, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI146231952, Length=339, Percent_Identity=32.1533923303835, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI223941776, Length=341, Percent_Identity=31.0850439882698, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI119120938, Length=330, Percent_Identity=27.8787878787879, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI87082430, Length=312, Percent_Identity=32.6923076923077, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788499, Length=227, Percent_Identity=30.3964757709251, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324356, Length=222, Percent_Identity=34.2342342342342, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 37046; Mature: 37046

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSLELNIPKRGMPVTIITGFLGSGKTTLINQILQNKQDLKVAVLVNEFGDLNIDTQLL
CCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHH
TDMNDNMIELSNGCICCTINEGLVDAVYQVLESDKKIDYLIIETTGVADPLPIILTFLST
HCCCCCEEEECCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHH
DLKDLTHLDSVLTLVDCENFTPDHFDSEAAFKQIAYGDIIILNKIDLASQDKVDYLDSYI
HHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
KTIRSGARILRSEHSNIPSYLILDVNISRLQPYSLEDNNDHSKLQKNPKDHLINDGFMSV
HHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCCCCCCCCCCHHHHHCCCHHHCCCCCEEEE
SFQSTRPFSALKFQHNFIEELPDNVFRAKGILWFQESESKHIFQLSGKRYEMEIDEWSTT
EECCCCCCHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCEEEEECCCEEEEEECCCCCC
PTNQLVLIGRNLDPLIIQQNLTNCLTM
CCCEEEEEECCCCCEEEHHHHHHHHCC
>Mature Secondary Structure
MNNSLELNIPKRGMPVTIITGFLGSGKTTLINQILQNKQDLKVAVLVNEFGDLNIDTQLL
CCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHH
TDMNDNMIELSNGCICCTINEGLVDAVYQVLESDKKIDYLIIETTGVADPLPIILTFLST
HCCCCCEEEECCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHH
DLKDLTHLDSVLTLVDCENFTPDHFDSEAAFKQIAYGDIIILNKIDLASQDKVDYLDSYI
HHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
KTIRSGARILRSEHSNIPSYLILDVNISRLQPYSLEDNNDHSKLQKNPKDHLINDGFMSV
HHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCCCCCCCCCCHHHHHCCCHHHCCCCCEEEE
SFQSTRPFSALKFQHNFIEELPDNVFRAKGILWFQESESKHIFQLSGKRYEMEIDEWSTT
EECCCCCCHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCEEEEECCCEEEEEECCCCCC
PTNQLVLIGRNLDPLIIQQNLTNCLTM
CCCEEEEEECCCCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]