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The map label for this gene is cry [H]

Identifier: 113477930

GI number: 113477930

Start: 7002260

End: 7003756

Strand: Reverse

Name: cry [H]

Synonym: Tery_4538

Alternate gene names: 113477930

Gene position: 7003756-7002260 (Counterclockwise)

Preceding gene: 113477937

Following gene: 113477929

Centisome position: 90.37

GC content: 32.06

Gene sequence:

>1497_bases
ATGAGTCAAAACGTAATTATATTATGGTATCGTAATGACCTACGCATCCATGACCATGAACCACTATATAAAGCACTCAA
AGTTAATGCTCAAATTATACCGATTTATTGTTTAGATCCAAGGCAATTTAGTCAAACAGATTTTGGTTTTCCTAAAACAG
GTGTATTTAGAGCAAAGTTTTTACTAGAAAGTATTGCTGATTTGCGTAACAACCTACAAAAATTAGGTAGTAATTTAGTT
ATTTTTCAAGATAAACCAGAAATAGTAATTCCTAGACTAGCTCAACAATTATCTGCTAAATCAGTATTTTTTCATCAAGA
AGTTACTGAGCTCGAAGTTAAAGTAGAAAGATTAGTTCATCAAGCACTAAAACAAATTGGAGTTAGGTTAAAATCATTTT
GGGGTCATACACTTTACCATCCAGATGATTTACCTTTTGAAATAAAACAATTACCAGAATTATTTACTACTTTTCGTAAA
GATGTAGAGAAAAATTCTAGTGTAAACCCTACATTCTCAATCCCTAAAAAATTATCATCCTTACCAAAAATTGATGTGGG
AGAATTACCTACATTATCTGATTTAAATCTAGAAAAACCGCCACTAAATTCACAGGGAGTTTTAGAATTTAAAGGTGGAG
AAACTGCCGCTAAGGAAAGAGTAAAAAACTACTTTTGGCAGCAAGACTATTTAAAAGTTTATAAGGAAACCAGAAATGGA
ATGCTAGGTGCCAATTATTCTTCTAAATTTTCCCCTTGGTTAGCTTTAGGATGTTTGTCACCTCGTTATATTTATGAAGA
AGTTAAAGAATATGAATATCAAAGAGTCAAGAATCAATCAACTTATTGGTTAATATTTGAGTTAATATGGCGAGATTACT
TCCGATTTATTTGTCAAAAACATGGGAATAAAATATTTCATAAATCTGGTTTACAAGGTATAGCTATTCCTTGGCAAGAG
GATTGGGAAAAATTTAGAAAGTGGCAAGCAGGTCAAACAGGATTTCCTCTAGTAGATGCTAATATGCGTGAACTTTTAGC
TACAGGTTTTATGTCAAATCGTGGTCGACAAAATGTTGCTAGTTTTCTTACTAAAAATTTAGGAATTAATTGGCAAATGG
GAGCTGAATGGTTTGAGTCTTTACTAATAGATTATGATGTTTGTAGTAATTGGGGAAATTGGAATTACACTGCTGGAGTA
GGAAATGATGGGCGAGGTTTTCGCTATTTTAATATTCCTAAACAAGCAAAAGATTACGACCCAGAAGGAAAATATGTTAA
ACATTGGTTACCAGAATTAGGAAAAGTTCCTCCTGCTAAAGTACATGAACCTTGGAAATTATTACCTGTTGAACAAGATA
GATTTGGTGTCAAAATAGGGGTAGATTATCCAGAACCAATTATTGATTTATGGCAGTCAGTTAAGGAGAATGAAAAAAAA
TATAATAGAGCGTTACAAATGACACTAGGTAAAATAAATAAAAGAGGCAGATTTTGA

Upstream 100 bases:

>100_bases
TTGGTATCATCCAAAATACTAAAGATAAAGGATATCAGCAACATTATTCAATTATCCTAGTTTTTCCTATTTTCCATTCC
TTATTCCCTCAAAAATTAAT

Downstream 100 bases:

>100_bases
ACAGGAATAAATTGTAAATTAGGATAATTCATAATTATAATTAACAGCAAAATCACCTCAATTTTTTGGTAGTTAGTTCA
TGTTTAATGATATTAATAAT

Product: deoxyribodipyrimidine photo-lyase type I

Products: 2 pyrimidine residues (in DNA) [C]

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSQNVIILWYRNDLRIHDHEPLYKALKVNAQIIPIYCLDPRQFSQTDFGFPKTGVFRAKFLLESIADLRNNLQKLGSNLV
IFQDKPEIVIPRLAQQLSAKSVFFHQEVTELEVKVERLVHQALKQIGVRLKSFWGHTLYHPDDLPFEIKQLPELFTTFRK
DVEKNSSVNPTFSIPKKLSSLPKIDVGELPTLSDLNLEKPPLNSQGVLEFKGGETAAKERVKNYFWQQDYLKVYKETRNG
MLGANYSSKFSPWLALGCLSPRYIYEEVKEYEYQRVKNQSTYWLIFELIWRDYFRFICQKHGNKIFHKSGLQGIAIPWQE
DWEKFRKWQAGQTGFPLVDANMRELLATGFMSNRGRQNVASFLTKNLGINWQMGAEWFESLLIDYDVCSNWGNWNYTAGV
GNDGRGFRYFNIPKQAKDYDPEGKYVKHWLPELGKVPPAKVHEPWKLLPVEQDRFGVKIGVDYPEPIIDLWQSVKENEKK
YNRALQMTLGKINKRGRF

Sequences:

>Translated_498_residues
MSQNVIILWYRNDLRIHDHEPLYKALKVNAQIIPIYCLDPRQFSQTDFGFPKTGVFRAKFLLESIADLRNNLQKLGSNLV
IFQDKPEIVIPRLAQQLSAKSVFFHQEVTELEVKVERLVHQALKQIGVRLKSFWGHTLYHPDDLPFEIKQLPELFTTFRK
DVEKNSSVNPTFSIPKKLSSLPKIDVGELPTLSDLNLEKPPLNSQGVLEFKGGETAAKERVKNYFWQQDYLKVYKETRNG
MLGANYSSKFSPWLALGCLSPRYIYEEVKEYEYQRVKNQSTYWLIFELIWRDYFRFICQKHGNKIFHKSGLQGIAIPWQE
DWEKFRKWQAGQTGFPLVDANMRELLATGFMSNRGRQNVASFLTKNLGINWQMGAEWFESLLIDYDVCSNWGNWNYTAGV
GNDGRGFRYFNIPKQAKDYDPEGKYVKHWLPELGKVPPAKVHEPWKLLPVEQDRFGVKIGVDYPEPIIDLWQSVKENEKK
YNRALQMTLGKINKRGRF
>Mature_497_residues
SQNVIILWYRNDLRIHDHEPLYKALKVNAQIIPIYCLDPRQFSQTDFGFPKTGVFRAKFLLESIADLRNNLQKLGSNLVI
FQDKPEIVIPRLAQQLSAKSVFFHQEVTELEVKVERLVHQALKQIGVRLKSFWGHTLYHPDDLPFEIKQLPELFTTFRKD
VEKNSSVNPTFSIPKKLSSLPKIDVGELPTLSDLNLEKPPLNSQGVLEFKGGETAAKERVKNYFWQQDYLKVYKETRNGM
LGANYSSKFSPWLALGCLSPRYIYEEVKEYEYQRVKNQSTYWLIFELIWRDYFRFICQKHGNKIFHKSGLQGIAIPWQED
WEKFRKWQAGQTGFPLVDANMRELLATGFMSNRGRQNVASFLTKNLGINWQMGAEWFESLLIDYDVCSNWGNWNYTAGVG
NDGRGFRYFNIPKQAKDYDPEGKYVKHWLPELGKVPPAKVHEPWKLLPVEQDRFGVKIGVDYPEPIIDLWQSVKENEKKY
NRALQMTLGKINKRGRF

Specific function: May have a photoreceptor function. Binds DNA; probably functions as a transcriptional repressor [H]

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI188536100, Length=495, Percent_Identity=27.6767676767677, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI4758072, Length=503, Percent_Identity=28.4294234592445, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI188536103, Length=449, Percent_Identity=27.8396436525612, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1786926, Length=470, Percent_Identity=30, Blast_Score=182, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324962, Length=532, Percent_Identity=27.2556390977444, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17137248, Length=505, Percent_Identity=29.3069306930693, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24585455, Length=505, Percent_Identity=29.3069306930693, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24648152, Length=505, Percent_Identity=26.9306930693069, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR014133
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: 4.1.99.3 [C]

Molecular weight: Translated: 58245; Mature: 58113

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00394 DNA_PHOTOLYASES_1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNVIILWYRNDLRIHDHEPLYKALKVNAQIIPIYCLDPRQFSQTDFGFPKTGVFRAKF
CCCCEEEEEECCCCEECCCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHH
LLESIADLRNNLQKLGSNLVIFQDKPEIVIPRLAQQLSAKSVFFHQEVTELEVKVERLVH
HHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALKQIGVRLKSFWGHTLYHPDDLPFEIKQLPELFTTFRKDVEKNSSVNPTFSIPKKLSS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
LPKIDVGELPTLSDLNLEKPPLNSQGVLEFKGGETAAKERVKNYFWQQDYLKVYKETRNG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
MLGANYSSKFSPWLALGCLSPRYIYEEVKEYEYQRVKNQSTYWLIFELIWRDYFRFICQK
EECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
HGNKIFHKSGLQGIAIPWQEDWEKFRKWQAGQTGFPLVDANMRELLATGFMSNRGRQNVA
HCCEEEHHCCCCCEECCCHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHH
SFLTKNLGINWQMGAEWFESLLIDYDVCSNWGNWNYTAGVGNDGRGFRYFNIPKQAKDYD
HHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEECCCCCCCCCC
PEGKYVKHWLPELGKVPPAKVHEPWKLLPVEQDRFGVKIGVDYPEPIIDLWQSVKENEKK
CCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
YNRALQMTLGKINKRGRF
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQNVIILWYRNDLRIHDHEPLYKALKVNAQIIPIYCLDPRQFSQTDFGFPKTGVFRAKF
CCCEEEEEECCCCEECCCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHH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HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: ATP; FADH2; Flavin; pterin [C]

Metal ions: NA

Kcat value (1/min): 2.4 [C]

Specific activity: NA

Km value (mM): NA

Substrates: cyclobutadipyrimidine (in DNA) [C]

Specific reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA) [C]

General reaction: C-C-bond cleavage [C]

Inhibitor: yeast DNA [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]