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The map label for this gene is nagA [H]

Identifier: 113477873

GI number: 113477873

Start: 6906691

End: 6907881

Strand: Reverse

Name: nagA [H]

Synonym: Tery_4474

Alternate gene names: 113477873

Gene position: 6907881-6906691 (Counterclockwise)

Preceding gene: 113477879

Following gene: 113477872

Centisome position: 89.13

GC content: 36.69

Gene sequence:

>1191_bases
GTGAACTTAACTACTAAAATTATTAATGCTAAGGTCCCTGGTTATCAAAACCTACAGCAAATTTTCATCAATTCTACTGG
CAATATTGAGAAAATTATCCCTCAAAATGGAGAGGCTTTGCCTAGCACATCTACTACTATTGATGTGGAACAAGACTGGG
TTTCTCTCGGAGGGTTTGATTTACAAATTAATGGTGCTTTGGGTTTACCTTTTCCGGAAGTAGATGAAACTTCAATAACT
AAAATACATGAAATTTGTCAATATTTATGGCACCAGGGAATAGATGCTTTTTTGCCTACTATTGTCACAACTTCTATAGA
TAATATTCAGCGATCGCTCCAAATCTTCGACTATTTGGCCTCACAACCCCAAGAACCAAAAACAGCTAAAATTTGGGGCG
TACATTTGGAAGGGCCTTTTTTGCATCCAGAAAAGCGGGGCGCTCACCCTCAGAAATATTTGCTACCATTAAGCATCGAA
AATGTCAAGCAGGTAATCGGCGATTATAGTCAGACAGTTAAAATTATCACTTTAGCACCGGAATTAGACAGTACAGAAAC
AATAATTCCTTACCTAAAAAATCTAGGAATTATAGTTAGTTTAGGGCATTCTCAGGCGACAGCAAATCAAGCAGAAACAG
CTTTTAAATTAGGAGCTTCAATGGTAACTCATGCCTTCAATGCTATGGGCAGTTTACATCATCGAAAACCAGGATTATTA
GGAGCAGCAATTACAAATTCTGAGGTTATGTGTGGTTTAATTGCTGATGGTCAGCATGTCTGTTCAACAATGATAGAAAT
TTTGTTAAAAGCAAGTCAATATCAGCAAGGAATATTTTTGGTTAGTGATGCTTTGGCGCCTTTGGGATTACCTGATGGAA
TTTACCCTTGGGATGCTAGAGAAATAGAAGTTAAAAATGGTACGGTTAGATTACAAGATGGAATATTAGCGGGAACAACT
TTACCTTTATTGGTTGGAGTTAATAATTTGGTAAAGTGGGGGGTTTGTGATATTGAAACTGCAATTAATTTAGGGACTAT
TGCACCTCGGAAAGCTTTAGGAATAGACAGTAAAATTATTGGGAAGTCTGGAAATAGTTTATTAAGGTGGCGGGTAAATA
GTCAGTTATTTAATAAGGAGATAGAGTTGGTTTGGCAGAGAATATTTGGAGTTGATTACATAGATAGATAA

Upstream 100 bases:

>100_bases
TCCATGTTGGGATATTGATTTCCCAAAAAAAATCTAAAATTCTCTTTTATTTTAACATAATTTTTTATAGTTGATAAAAT
ATAACTTGGAATTTAAACCC

Downstream 100 bases:

>100_bases
ATAAAGTATTGATGGTTTTGTTAGAAATTAAAGCATAAGTTTAGGGATGCAGCTTTTAGTTTATGGTTAAGGGCTGAGTG
CTTAAATTTGCAGATTTTTT

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNLTTKIINAKVPGYQNLQQIFINSTGNIEKIIPQNGEALPSTSTTIDVEQDWVSLGGFDLQINGALGLPFPEVDETSIT
KIHEICQYLWHQGIDAFLPTIVTTSIDNIQRSLQIFDYLASQPQEPKTAKIWGVHLEGPFLHPEKRGAHPQKYLLPLSIE
NVKQVIGDYSQTVKIITLAPELDSTETIIPYLKNLGIIVSLGHSQATANQAETAFKLGASMVTHAFNAMGSLHHRKPGLL
GAAITNSEVMCGLIADGQHVCSTMIEILLKASQYQQGIFLVSDALAPLGLPDGIYPWDAREIEVKNGTVRLQDGILAGTT
LPLLVGVNNLVKWGVCDIETAINLGTIAPRKALGIDSKIIGKSGNSLLRWRVNSQLFNKEIELVWQRIFGVDYIDR

Sequences:

>Translated_396_residues
MNLTTKIINAKVPGYQNLQQIFINSTGNIEKIIPQNGEALPSTSTTIDVEQDWVSLGGFDLQINGALGLPFPEVDETSIT
KIHEICQYLWHQGIDAFLPTIVTTSIDNIQRSLQIFDYLASQPQEPKTAKIWGVHLEGPFLHPEKRGAHPQKYLLPLSIE
NVKQVIGDYSQTVKIITLAPELDSTETIIPYLKNLGIIVSLGHSQATANQAETAFKLGASMVTHAFNAMGSLHHRKPGLL
GAAITNSEVMCGLIADGQHVCSTMIEILLKASQYQQGIFLVSDALAPLGLPDGIYPWDAREIEVKNGTVRLQDGILAGTT
LPLLVGVNNLVKWGVCDIETAINLGTIAPRKALGIDSKIIGKSGNSLLRWRVNSQLFNKEIELVWQRIFGVDYIDR
>Mature_396_residues
MNLTTKIINAKVPGYQNLQQIFINSTGNIEKIIPQNGEALPSTSTTIDVEQDWVSLGGFDLQINGALGLPFPEVDETSIT
KIHEICQYLWHQGIDAFLPTIVTTSIDNIQRSLQIFDYLASQPQEPKTAKIWGVHLEGPFLHPEKRGAHPQKYLLPLSIE
NVKQVIGDYSQTVKIITLAPELDSTETIIPYLKNLGIIVSLGHSQATANQAETAFKLGASMVTHAFNAMGSLHHRKPGLL
GAAITNSEVMCGLIADGQHVCSTMIEILLKASQYQQGIFLVSDALAPLGLPDGIYPWDAREIEVKNGTVRLQDGILAGTT
LPLLVGVNNLVKWGVCDIETAINLGTIAPRKALGIDSKIIGKSGNSLLRWRVNSQLFNKEIELVWQRIFGVDYIDR

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=338, Percent_Identity=30.7692307692308, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI224922791, Length=338, Percent_Identity=30.7692307692308, Blast_Score=158, Evalue=9e-39,
Organism=Escherichia coli, GI1786892, Length=317, Percent_Identity=32.1766561514196, Blast_Score=159, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17553768, Length=327, Percent_Identity=33.3333333333333, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19920392, Length=321, Percent_Identity=33.9563862928349, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI281361140, Length=335, Percent_Identity=33.134328358209, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 43416; Mature: 43416

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTTKIINAKVPGYQNLQQIFINSTGNIEKIIPQNGEALPSTSTTIDVEQDWVSLGGFD
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEECHHHHHCCCEE
LQINGALGLPFPEVDETSITKIHEICQYLWHQGIDAFLPTIVTTSIDNIQRSLQIFDYLA
EEECCEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQPQEPKTAKIWGVHLEGPFLHPEKRGAHPQKYLLPLSIENVKQVIGDYSQTVKIITLAP
CCCCCCCCEEEEEEEECCCCCCCHHCCCCCCCEEEECCHHHHHHHHCCCCCEEEEEEECC
ELDSTETIIPYLKNLGIIVSLGHSQATANQAETAFKLGASMVTHAFNAMGSLHHRKPGLL
CCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
GAAITNSEVMCGLIADGQHVCSTMIEILLKASQYQQGIFLVSDALAPLGLPDGIYPWDAR
EEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC
EIEVKNGTVRLQDGILAGTTLPLLVGVNNLVKWGVCDIETAINLGTIAPRKALGIDSKII
EEEEECCEEEEECCEEECCHHHHHHHHHHHHHCCCEEHHHHCCCCCCCCHHHCCCCCCEE
GKSGNSLLRWRVNSQLFNKEIELVWQRIFGVDYIDR
CCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNLTTKIINAKVPGYQNLQQIFINSTGNIEKIIPQNGEALPSTSTTIDVEQDWVSLGGFD
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEECHHHHHCCCEE
LQINGALGLPFPEVDETSITKIHEICQYLWHQGIDAFLPTIVTTSIDNIQRSLQIFDYLA
EEECCEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQPQEPKTAKIWGVHLEGPFLHPEKRGAHPQKYLLPLSIENVKQVIGDYSQTVKIITLAP
CCCCCCCCEEEEEEEECCCCCCCHHCCCCCCCEEEECCHHHHHHHHCCCCCEEEEEEECC
ELDSTETIIPYLKNLGIIVSLGHSQATANQAETAFKLGASMVTHAFNAMGSLHHRKPGLL
CCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
GAAITNSEVMCGLIADGQHVCSTMIEILLKASQYQQGIFLVSDALAPLGLPDGIYPWDAR
EEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC
EIEVKNGTVRLQDGILAGTTLPLLVGVNNLVKWGVCDIETAINLGTIAPRKALGIDSKII
EEEEECCEEEEECCEEECCHHHHHHHHHHHHHCCCEEHHHHCCCCCCCCHHHCCCCCCEE
GKSGNSLLRWRVNSQLFNKEIELVWQRIFGVDYIDR
CCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]