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The map label for this gene is phoB [H]

Identifier: 113477729

GI number: 113477729

Start: 6666903

End: 6667550

Strand: Reverse

Name: phoB [H]

Synonym: Tery_4323

Alternate gene names: 113477729

Gene position: 6667550-6666903 (Counterclockwise)

Preceding gene: 113477730

Following gene: 113477728

Centisome position: 86.03

GC content: 37.96

Gene sequence:

>648_bases
ATGAAGGAAACAAACGCTATAAATACAAAACATTTAATGTTAGTTGACGATGACCCTAATTTAATCTTATTAGTGAAAGA
TTATTTAGAATTTCGCGGATATCAGGTAATAACAGCAGAAAATGGCCGAGAAGCTCTAGAACTTTTAGAAGAACAAATTC
CTGACCTGATTATATGTGATGTGATGATGCCACAAATGAATGGCTACAACCTAGTGCAGCATATCAGAGAAAATTTAGCT
ACAGAATGGGTTCCAGTTCTATTTTTATCTGCAAAGGGTCAAATTCAGGATCGAGTTAAGGGTCTTAATACTGGAGCTGA
CGTCTACATTGTCAAGCCATTTGAACCTGAAGAACTTGTGGCTCAAGTAGAATCTTCTCTTAAACAAGCTTCTCGCCTAA
TTAAACATCACAATTCCAGTTTTAGCGATAGGCCAACAATTAAGGTACGCCGAAACGTAGAGTTGACTCCCAGAGAGTTA
AAAGTAGTCAAATTAGTAGCCCAGGGAATGGCTAATCGTGACATTGCAGAAATTATGGAAGTTAGTCAAAGAACGATCGA
AAGTCATGTGAGCAATATGCTTGGTAAAACTGGTCTACATAATCGGACCGAGTTAGCTCGTTGGGCAATTGAAAGTAAGA
AGGCTTAA

Upstream 100 bases:

>100_bases
GTAAACCTGTCCTACTTCCAACTGTATCTTATGAAATAAGTGGGCTCACCCCTCTGTAAAGTTAATATTTTTAGGAATCA
AAAAAGTGAGTTCTTCAATT

Downstream 100 bases:

>100_bases
GTTTTGATATAAGTTTCCAAGAATCTATCAGGATTTAAGTTTTTATCTATCTAATTTCTGAATTATAGGGCTGTAATTTT
CTACTGCCCACAATTTTCTA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKETNAINTKHLMLVDDDPNLILLVKDYLEFRGYQVITAENGREALELLEEQIPDLIICDVMMPQMNGYNLVQHIRENLA
TEWVPVLFLSAKGQIQDRVKGLNTGADVYIVKPFEPEELVAQVESSLKQASRLIKHHNSSFSDRPTIKVRRNVELTPREL
KVVKLVAQGMANRDIAEIMEVSQRTIESHVSNMLGKTGLHNRTELARWAIESKKA

Sequences:

>Translated_215_residues
MKETNAINTKHLMLVDDDPNLILLVKDYLEFRGYQVITAENGREALELLEEQIPDLIICDVMMPQMNGYNLVQHIRENLA
TEWVPVLFLSAKGQIQDRVKGLNTGADVYIVKPFEPEELVAQVESSLKQASRLIKHHNSSFSDRPTIKVRRNVELTPREL
KVVKLVAQGMANRDIAEIMEVSQRTIESHVSNMLGKTGLHNRTELARWAIESKKA
>Mature_215_residues
MKETNAINTKHLMLVDDDPNLILLVKDYLEFRGYQVITAENGREALELLEEQIPDLIICDVMMPQMNGYNLVQHIRENLA
TEWVPVLFLSAKGQIQDRVKGLNTGADVYIVKPFEPEELVAQVESSLKQASRLIKHHNSSFSDRPTIKVRRNVELTPREL
KVVKLVAQGMANRDIAEIMEVSQRTIESHVSNMLGKTGLHNRTELARWAIESKKA

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=123, Percent_Identity=38.2113821138211, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788394, Length=203, Percent_Identity=29.064039408867, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786784, Length=140, Percent_Identity=34.2857142857143, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367329, Length=206, Percent_Identity=33.9805825242718, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI87082012, Length=167, Percent_Identity=32.9341317365269, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=34.1666666666667, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=35.3448275862069, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=28.0612244897959, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787375, Length=160, Percent_Identity=33.75, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1788905, Length=121, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1786747, Length=181, Percent_Identity=27.0718232044199, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1790102, Length=171, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1788550, Length=140, Percent_Identity=29.2857142857143, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787473, Length=206, Percent_Identity=35.4368932038835, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789402, Length=202, Percent_Identity=29.2079207920792, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790860, Length=121, Percent_Identity=35.5371900826446, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1790863, Length=127, Percent_Identity=33.0708661417323, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787487, Length=110, Percent_Identity=35.4545454545455, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=185, Percent_Identity=29.1891891891892, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790552, Length=208, Percent_Identity=30.2884615384615, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787229, Length=117, Percent_Identity=32.4786324786325, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786911, Length=164, Percent_Identity=28.6585365853659, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=36.2745098039216, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=36.8932038834951, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24482; Mature: 24482

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETNAINTKHLMLVDDDPNLILLVKDYLEFRGYQVITAENGREALELLEEQIPDLIICD
CCCCCCCCCEEEEEEECCCCEEEEEEHHHHHCCEEEEEECCCHHHHHHHHHHCCCEEEEH
VMMPQMNGYNLVQHIRENLATEWVPVLFLSAKGQIQDRVKGLNTGADVYIVKPFEPEELV
HHCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHCCCCCCCEEEECCCCHHHHH
AQVESSLKQASRLIKHHNSSFSDRPTIKVRRNVELTPRELKVVKLVAQGMANRDIAEIME
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
VSQRTIESHVSNMLGKTGLHNRTELARWAIESKKA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKETNAINTKHLMLVDDDPNLILLVKDYLEFRGYQVITAENGREALELLEEQIPDLIICD
CCCCCCCCCEEEEEEECCCCEEEEEEHHHHHCCEEEEEECCCHHHHHHHHHHCCCEEEEH
VMMPQMNGYNLVQHIRENLATEWVPVLFLSAKGQIQDRVKGLNTGADVYIVKPFEPEELV
HHCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHCCCCCCCEEEECCCCHHHHH
AQVESSLKQASRLIKHHNSSFSDRPTIKVRRNVELTPRELKVVKLVAQGMANRDIAEIME
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
VSQRTIESHVSNMLGKTGLHNRTELARWAIESKKA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]