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The map label for this gene is trxC [C]

Identifier: 113476942

GI number: 113476942

Start: 5256465

End: 5256788

Strand: Reverse

Name: trxC [C]

Synonym: Tery_3437

Alternate gene names: 113476942

Gene position: 5256788-5256465 (Counterclockwise)

Preceding gene: 113476945

Following gene: 113476941

Centisome position: 67.83

GC content: 34.88

Gene sequence:

>324_bases
ATGGCAATTAAAAAGAAGTTTAATAATTTTGATGAATTACTTGCTGGTTCAGATCTACCCGTTTTAGTCGATTTTTATGC
CACCTGGTGTGGCCCTTGCAAGATGATGACCCCTATTCTAGAACAGGTAAATCAACAAATCAAAGATAAACTGCGAATAG
TTAAAATTGATACAGATAAATATCCTCAGTTAGCATCTCGTTATCATATTGAATCCCTACCCACTTTAGTCCTGTTTAAA
AATGGTCAGCCAGTAGACAGAATAGAAGGAGTAATACAATCACCACAATTAGTGGAACGCTTAAATAAGATGACCTCAAT
TTAA

Upstream 100 bases:

>100_bases
AAGTAGGCATTGGGAAATACCCCCTCAGTGAGTTAATCTTACTGTGCATTGTTAATAATTATTAGCAATCATAATATCAG
TTCTAATAAATTTTTTTATT

Downstream 100 bases:

>100_bases
TTAAATTTTCTTGCAGAATATAGAGATAATTTTCACTAAGTATTTAAGATAACTGCTCCTGACAATAGAAGTAAAAATAT
GCTAAAATTAGATTATAAAT

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MAIKKKFNNFDELLAGSDLPVLVDFYATWCGPCKMMTPILEQVNQQIKDKLRIVKIDTDKYPQLASRYHIESLPTLVLFK
NGQPVDRIEGVIQSPQLVERLNKMTSI

Sequences:

>Translated_107_residues
MAIKKKFNNFDELLAGSDLPVLVDFYATWCGPCKMMTPILEQVNQQIKDKLRIVKIDTDKYPQLASRYHIESLPTLVLFK
NGQPVDRIEGVIQSPQLVERLNKMTSI
>Mature_106_residues
AIKKKFNNFDELLAGSDLPVLVDFYATWCGPCKMMTPILEQVNQQIKDKLRIVKIDTDKYPQLASRYHIESLPTLVLFKN
GQPVDRIEGVIQSPQLVERLNKMTSI

Specific function: Efficient Electron Donor For The Essential Enzyme Ribonucleotide Reductase. Is Also Able To Reduce The Interchain Disulfide Bridges Of Insulin. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=96, Percent_Identity=37.5, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI4758304, Length=100, Percent_Identity=37, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI50592994, Length=83, Percent_Identity=37.3493975903614, Blast_Score=66, Evalue=5e-12,
Organism=Homo sapiens, GI52487191, Length=85, Percent_Identity=37.6470588235294, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788936, Length=101, Percent_Identity=42.5742574257426, Blast_Score=93, Evalue=4e-21,
Organism=Escherichia coli, GI87082331, Length=95, Percent_Identity=41.0526315789474, Blast_Score=89, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI212646193, Length=89, Percent_Identity=38.2022471910112, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17507705, Length=73, Percent_Identity=36.986301369863, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17509965, Length=72, Percent_Identity=40.2777777777778, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71998175, Length=88, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71980565, Length=73, Percent_Identity=35.6164383561644, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71980562, Length=73, Percent_Identity=35.6164383561644, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32566189, Length=80, Percent_Identity=36.25, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17569137, Length=80, Percent_Identity=36.25, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193209454, Length=80, Percent_Identity=36.25, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115532254, Length=83, Percent_Identity=36.144578313253, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532252, Length=100, Percent_Identity=34, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17511147, Length=68, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144092, Length=81, Percent_Identity=35.8024691358025, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17554386, Length=101, Percent_Identity=30.6930693069307, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=87, Percent_Identity=40.2298850574713, Blast_Score=85, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323072, Length=87, Percent_Identity=41.3793103448276, Blast_Score=79, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319925, Length=94, Percent_Identity=40.4255319148936, Blast_Score=74, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573567, Length=95, Percent_Identity=38.9473684210526, Blast_Score=85, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17648013, Length=88, Percent_Identity=39.7727272727273, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583090, Length=88, Percent_Identity=39.7727272727273, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24664269, Length=94, Percent_Identity=38.2978723404255, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17530795, Length=92, Percent_Identity=33.695652173913, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639826, Length=96, Percent_Identity=32.2916666666667, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358065, Length=83, Percent_Identity=38.5542168674699, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17647799, Length=101, Percent_Identity=34.6534653465347, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639068, Length=98, Percent_Identity=31.6326530612245, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 12279; Mature: 12147

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKKKFNNFDELLAGSDLPVLVDFYATWCGPCKMMTPILEQVNQQIKDKLRIVKIDTDK
CCCHHHHCCHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCC
YPQLASRYHIESLPTLVLFKNGQPVDRIEGVIQSPQLVERLNKMTSI
CHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AIKKKFNNFDELLAGSDLPVLVDFYATWCGPCKMMTPILEQVNQQIKDKLRIVKIDTDK
CCHHHHCCHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCC
YPQLASRYHIESLPTLVLFKNGQPVDRIEGVIQSPQLVERLNKMTSI
CHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]