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The map label for this gene is mrdB [H]

Identifier: 113476820

GI number: 113476820

Start: 5064988

End: 5066241

Strand: Reverse

Name: mrdB [H]

Synonym: Tery_3302

Alternate gene names: 113476820

Gene position: 5066241-5064988 (Counterclockwise)

Preceding gene: 113476821

Following gene: 113476819

Centisome position: 65.37

GC content: 37.16

Gene sequence:

>1254_bases
ATGACGAATAAATTAGTCTTAAGAAATGGCCGAAAATCACTCCTTTCAAGCTGGAAATATATAGATTGTAAATTACTACT
GGTTTATATAGGAATGACGATCTTTGGTGGAATTATAATCCAAAGTGTGGAAAAAAATCAGGGGCTGACAGACTGGTGGC
AGCATTGGCTTACAGGAGGAGTAGGTTTGATTTTGGCCCTAATTATTGCTCGTTGTCGCTACGAAGTGTTAGTTCGCTGG
AAATGGGCAATTTACATTTTGACCAATATTTCCCTAGTTGCGGTACAGGCTCTAGGTACTTCAGCTCTGGGAGCACAACG
GTGGATTAATGTTGCTGGCTTTCATGTTCAACCTTCGGAATTCGCTAAGGTGGGAATAATTATTACTTTGGCAGCAATAC
TTTCTTCTAAGCCTAAGGTAAAGCTATTCGATTTGTTTCAAGTTCTAATTGTTACAGCCATTCCCTGGCTATTAGTTTTT
TTAGAACCAAATCTGGGTACTTCATTAATATTTGGTGTTATTACTATAGGAATGCTTTACTGGGGTAATATTAATCCTGG
GTGGTTAATATTACTTGTCTCTCCCATTTTCTCAATTATTCTTCATAATCTATATACCCCTGCTTGGTTTGCATGGATAA
CTCTGATGGCCTTAATAGCTTGGCGTAGTCTACCTTGGGGATGGTTATGGACGCCTATAGTTGCTGGTATTAATATTTGT
TCTTCAAATGTTGCGCAAACTTTATGGCATCTTCTCAAAGACTATCAAAAAGATAGATTAACGGGATTTCTTAATCCGGA
ACAAGACCCTTTGGGTACAGGATATCATTTGATTCAATCTCGCATTGCTATAGGATCTGGACAACTTTTTGGTAGAGGAT
TATATCAAGGCACTCAAACTCAACTGAATTTTATTCCAGAGCAACATACGGATTTTATCTTCTCAGCTATTGGGGAAGAG
TTTGGTTTCATTGGTTGTATTTTTGTACTGTTTGCTTTTTGGTTTATTTGTCTACGCTTGGTGATTATTGCTTACACTGC
TAAAGATAATTTTGGTTCTCTTATAGCCATTGGAGTATTATCAATGTTAATCTTCCAAGTTTTTGTAAATATTGGTATGA
ATATTGGTTTGGCTCCTGTGACTGGGATCCCACTACCTTTACTTAGTTATGGGCGTTCGGCTTTGTTGAGTAACTTTATT
GCTTTAGGACTAGTAGAGTCAGTGGCTAATAATAAACCTAAACAAAATTTTTGA

Upstream 100 bases:

>100_bases
TGAGTCAAAGAAAATTTGAATTTATGCAGACATTCCACCCTAGTAAATGTATTAGGTATAGAGAATACTATAAATTATAA
AGTATCTAAACTTTAAAAAT

Downstream 100 bases:

>100_bases
GGCTAAAATTGACAATCTCCTAACAGCAAGGTCAAAGAATAATATAGCAAATTTAGATCAATGTTGAGATACAATTATTC
TGGGGAATATACGGGCGCTA

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTNKLVLRNGRKSLLSSWKYIDCKLLLVYIGMTIFGGIIIQSVEKNQGLTDWWQHWLTGGVGLILALIIARCRYEVLVRW
KWAIYILTNISLVAVQALGTSALGAQRWINVAGFHVQPSEFAKVGIIITLAAILSSKPKVKLFDLFQVLIVTAIPWLLVF
LEPNLGTSLIFGVITIGMLYWGNINPGWLILLVSPIFSIILHNLYTPAWFAWITLMALIAWRSLPWGWLWTPIVAGINIC
SSNVAQTLWHLLKDYQKDRLTGFLNPEQDPLGTGYHLIQSRIAIGSGQLFGRGLYQGTQTQLNFIPEQHTDFIFSAIGEE
FGFIGCIFVLFAFWFICLRLVIIAYTAKDNFGSLIAIGVLSMLIFQVFVNIGMNIGLAPVTGIPLPLLSYGRSALLSNFI
ALGLVESVANNKPKQNF

Sequences:

>Translated_417_residues
MTNKLVLRNGRKSLLSSWKYIDCKLLLVYIGMTIFGGIIIQSVEKNQGLTDWWQHWLTGGVGLILALIIARCRYEVLVRW
KWAIYILTNISLVAVQALGTSALGAQRWINVAGFHVQPSEFAKVGIIITLAAILSSKPKVKLFDLFQVLIVTAIPWLLVF
LEPNLGTSLIFGVITIGMLYWGNINPGWLILLVSPIFSIILHNLYTPAWFAWITLMALIAWRSLPWGWLWTPIVAGINIC
SSNVAQTLWHLLKDYQKDRLTGFLNPEQDPLGTGYHLIQSRIAIGSGQLFGRGLYQGTQTQLNFIPEQHTDFIFSAIGEE
FGFIGCIFVLFAFWFICLRLVIIAYTAKDNFGSLIAIGVLSMLIFQVFVNIGMNIGLAPVTGIPLPLLSYGRSALLSNFI
ALGLVESVANNKPKQNF
>Mature_416_residues
TNKLVLRNGRKSLLSSWKYIDCKLLLVYIGMTIFGGIIIQSVEKNQGLTDWWQHWLTGGVGLILALIIARCRYEVLVRWK
WAIYILTNISLVAVQALGTSALGAQRWINVAGFHVQPSEFAKVGIIITLAAILSSKPKVKLFDLFQVLIVTAIPWLLVFL
EPNLGTSLIFGVITIGMLYWGNINPGWLILLVSPIFSIILHNLYTPAWFAWITLMALIAWRSLPWGWLWTPIVAGINICS
SNVAQTLWHLLKDYQKDRLTGFLNPEQDPLGTGYHLIQSRIAIGSGQLFGRGLYQGTQTQLNFIPEQHTDFIFSAIGEEF
GFIGCIFVLFAFWFICLRLVIIAYTAKDNFGSLIAIGVLSMLIFQVFVNIGMNIGLAPVTGIPLPLLSYGRSALLSNFIA
LGLVESVANNKPKQNF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=356, Percent_Identity=35.1123595505618, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786277, Length=400, Percent_Identity=30.25, Blast_Score=141, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46544; Mature: 46413

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKLVLRNGRKSLLSSWKYIDCKLLLVYIGMTIFGGIIIQSVEKNQGLTDWWQHWLTGG
CCCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGLILALIIARCRYEVLVRWKWAIYILTNISLVAVQALGTSALGAQRWINVAGFHVQPSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECHHH
FAKVGIIITLAAILSSKPKVKLFDLFQVLIVTAIPWLLVFLEPNLGTSLIFGVITIGMLY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WGNINPGWLILLVSPIFSIILHNLYTPAWFAWITLMALIAWRSLPWGWLWTPIVAGINIC
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SSNVAQTLWHLLKDYQKDRLTGFLNPEQDPLGTGYHLIQSRIAIGSGQLFGRGLYQGTQT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHCHHCCCCCH
QLNFIPEQHTDFIFSAIGEEFGFIGCIFVLFAFWFICLRLVIIAYTAKDNFGSLIAIGVL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SMLIFQVFVNIGMNIGLAPVTGIPLPLLSYGRSALLSNFIALGLVESVANNKPKQNF
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TNKLVLRNGRKSLLSSWKYIDCKLLLVYIGMTIFGGIIIQSVEKNQGLTDWWQHWLTGG
CCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGLILALIIARCRYEVLVRWKWAIYILTNISLVAVQALGTSALGAQRWINVAGFHVQPSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECHHH
FAKVGIIITLAAILSSKPKVKLFDLFQVLIVTAIPWLLVFLEPNLGTSLIFGVITIGMLY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WGNINPGWLILLVSPIFSIILHNLYTPAWFAWITLMALIAWRSLPWGWLWTPIVAGINIC
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SSNVAQTLWHLLKDYQKDRLTGFLNPEQDPLGTGYHLIQSRIAIGSGQLFGRGLYQGTQT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHCHHCCCCCH
QLNFIPEQHTDFIFSAIGEEFGFIGCIFVLFAFWFICLRLVIIAYTAKDNFGSLIAIGVL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SMLIFQVFVNIGMNIGLAPVTGIPLPLLSYGRSALLSNFIALGLVESVANNKPKQNF
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]