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The map label for this gene is gap3 [H]

Identifier: 113476798

GI number: 113476798

Start: 5022189

End: 5023211

Strand: Reverse

Name: gap3 [H]

Synonym: Tery_3274

Alternate gene names: 113476798

Gene position: 5023211-5022189 (Counterclockwise)

Preceding gene: 113476799

Following gene: 113476797

Centisome position: 64.81

GC content: 39.1

Gene sequence:

>1023_bases
ATGCGTATTGGAATAAATGGATTTGGTCGTATAGGAAGGCTGGCACTCCGTGCAGCTTGGGAATGGCCAGAACTAGAGTT
TGTTCACATTAATGAAATTAAAGGAGGTACGGCAGCAGCGGCACATTTACTCAAGTTTGATTCTGTACATGGCAAATGGT
CCCTGGACGTAGAAGCAGCAGGGGAGCAAGTAATAATTGATGGTAAACCTCTCAGTTTCAGTGAATATTCCGAACCAGGT
GAAGTACCTTGGGAAAAACTTGGTGTGGATATTGTATTAGAATGTTCTGGCAAGTTTAGAACTAAAAGTACTCTAGAACC
TTACTTTCAAAATGGTGTAAAAAAGGTTATTGTTGCCGCGCCAGTTAAAGAAGAAGCTTTAAATGTAGTTATGGGCGTCA
ATGATAATTTGTATGACCCCGAAAAACATCATTTACTTACAGCAGCTTCTTGTACCACAAATTGTTTGGCTCCAGTGGTT
AAAGTCATTCATGAAGGATTAGGAATTAAACATGGAGTTATTACTACTATTCATGACAATACTAACACTCAGATTATTGT
TGATGCACCTCATAAAGATTTGCGTCGTGCCAGAGCTACAAGTCTATCACTAATTCCTACTACAACTGGATCGGCAACAG
CGATCGGACTAATTTATCCGGAACTTAACGGTAAGTTGAATGGTTTAGCAGTACGAGTTCCTCTATTGAATGCTTCTTTG
ACAGACTGTGTCTTTGAAGTAGTTCGTCCTACCACAGTAGTTGAAATTAATAGCTTGCTCAAAACTGCATCTGAAACACC
ACCACTTAAAGGAATTTTGGGTTATGAAGAACGTCCTTTAGTTTCTATTGACTATAAAGATGACCCCCGGTCTTCTATTA
TTGATGCTCTTTCAACAATGGTAGTAGATGAAACTCAAGTGAAAATTTTGGCTTGGTATGATAATGAGTGGGGTTATGCT
AACCGTATGGTAGAGCTAGCTCGAAAAGTTGTTGTAAGTTGGAAATCTGGTTTGAGTTTCTAA

Upstream 100 bases:

>100_bases
CATACTCTTAAGCGATCGCTATAGTAGTAGGTTATCTTCATAAATTTTAGTTATTACAACACCCTTAAAAGGGAAACTTA
AAGAAGGAAAAAATATAGCA

Downstream 100 bases:

>100_bases
TGATTTAGATCTCTTCAGAATTGAAGGTTTAATTTTAGGAAATTGGTTGCAATAGTTTAAATTCATTAAAATTATGGTTT
CTACTACAAGTGCTAGTTTA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRIGINGFGRIGRLALRAAWEWPELEFVHINEIKGGTAAAAHLLKFDSVHGKWSLDVEAAGEQVIIDGKPLSFSEYSEPG
EVPWEKLGVDIVLECSGKFRTKSTLEPYFQNGVKKVIVAAPVKEEALNVVMGVNDNLYDPEKHHLLTAASCTTNCLAPVV
KVIHEGLGIKHGVITTIHDNTNTQIIVDAPHKDLRRARATSLSLIPTTTGSATAIGLIYPELNGKLNGLAVRVPLLNASL
TDCVFEVVRPTTVVEINSLLKTASETPPLKGILGYEERPLVSIDYKDDPRSSIIDALSTMVVDETQVKILAWYDNEWGYA
NRMVELARKVVVSWKSGLSF

Sequences:

>Translated_340_residues
MRIGINGFGRIGRLALRAAWEWPELEFVHINEIKGGTAAAAHLLKFDSVHGKWSLDVEAAGEQVIIDGKPLSFSEYSEPG
EVPWEKLGVDIVLECSGKFRTKSTLEPYFQNGVKKVIVAAPVKEEALNVVMGVNDNLYDPEKHHLLTAASCTTNCLAPVV
KVIHEGLGIKHGVITTIHDNTNTQIIVDAPHKDLRRARATSLSLIPTTTGSATAIGLIYPELNGKLNGLAVRVPLLNASL
TDCVFEVVRPTTVVEINSLLKTASETPPLKGILGYEERPLVSIDYKDDPRSSIIDALSTMVVDETQVKILAWYDNEWGYA
NRMVELARKVVVSWKSGLSF
>Mature_340_residues
MRIGINGFGRIGRLALRAAWEWPELEFVHINEIKGGTAAAAHLLKFDSVHGKWSLDVEAAGEQVIIDGKPLSFSEYSEPG
EVPWEKLGVDIVLECSGKFRTKSTLEPYFQNGVKKVIVAAPVKEEALNVVMGVNDNLYDPEKHHLLTAASCTTNCLAPVV
KVIHEGLGIKHGVITTIHDNTNTQIIVDAPHKDLRRARATSLSLIPTTTGSATAIGLIYPELNGKLNGLAVRVPLLNASL
TDCVFEVVRPTTVVEINSLLKTASETPPLKGILGYEERPLVSIDYKDDPRSSIIDALSTMVVDETQVKILAWYDNEWGYA
NRMVELARKVVVSWKSGLSF

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=41.2844036697248, Blast_Score=265, Evalue=4e-71,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=39.209726443769, Blast_Score=251, Evalue=7e-67,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=40.0611620795107, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=39.5136778115502, Blast_Score=252, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=41.6918429003021, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=41.3897280966767, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI17568413, Length=330, Percent_Identity=40.6060606060606, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI32566163, Length=330, Percent_Identity=40.6060606060606, Blast_Score=252, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=41.6918429003021, Blast_Score=269, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6322409, Length=327, Percent_Identity=41.2844036697248, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=40.785498489426, Blast_Score=267, Evalue=1e-72,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=38.7692307692308, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=39.9390243902439, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=39.9390243902439, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=39.0243902439024, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=39.0243902439024, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37244; Mature: 37244

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGINGFGRIGRLALRAAWEWPELEFVHINEIKGGTAAAAHLLKFDSVHGKWSLDVEAA
CEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECC
GEQVIIDGKPLSFSEYSEPGEVPWEKLGVDIVLECSGKFRTKSTLEPYFQNGVKKVIVAA
CCEEEECCCCCCHHCCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCHHHHCCCEEEEEEC
PVKEEALNVVMGVNDNLYDPEKHHLLTAASCTTNCLAPVVKVIHEGLGIKHGVITTIHDN
CCHHHHEEEEECCCCCCCCCCHHCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
TNTQIIVDAPHKDLRRARATSLSLIPTTTGSATAIGLIYPELNGKLNGLAVRVPLLNASL
CCCEEEEECCHHHHHHHHHCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEECCCHH
TDCVFEVVRPTTVVEINSLLKTASETPPLKGILGYEERPLVSIDYKDDPRSSIIDALSTM
HHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
VVDETQVKILAWYDNEWGYANRMVELARKVVVSWKSGLSF
HCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIGINGFGRIGRLALRAAWEWPELEFVHINEIKGGTAAAAHLLKFDSVHGKWSLDVEAA
CEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECC
GEQVIIDGKPLSFSEYSEPGEVPWEKLGVDIVLECSGKFRTKSTLEPYFQNGVKKVIVAA
CCEEEECCCCCCHHCCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCHHHHCCCEEEEEEC
PVKEEALNVVMGVNDNLYDPEKHHLLTAASCTTNCLAPVVKVIHEGLGIKHGVITTIHDN
CCHHHHEEEEECCCCCCCCCCHHCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
TNTQIIVDAPHKDLRRARATSLSLIPTTTGSATAIGLIYPELNGKLNGLAVRVPLLNASL
CCCEEEEECCHHHHHHHHHCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEECCCHH
TDCVFEVVRPTTVVEINSLLKTASETPPLKGILGYEERPLVSIDYKDDPRSSIIDALSTM
HHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
VVDETQVKILAWYDNEWGYANRMVELARKVVVSWKSGLSF
HCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]