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The map label for this gene is rfbH [H]

Identifier: 113475901

GI number: 113475901

Start: 3518190

End: 3519542

Strand: Direct

Name: rfbH [H]

Synonym: Tery_2261

Alternate gene names: 113475901

Gene position: 3518190-3519542 (Clockwise)

Preceding gene: 113475900

Following gene: 113475902

Centisome position: 45.4

GC content: 37.92

Gene sequence:

>1353_bases
ATGGAAGCTGAAAATCTCAAAGTGCAGATTTTAGAATTGGTTAAAAAATATTACCAAACAGCTCATCAAAAGTCTGGTTT
TGAACCAGGAAAAAGTCGAATTAACTACTCAGGAAGGGTTTATGACGATCAAGAATTGGTCAATTTAGTAGATTCTTCTC
TGGATTTTTGGTTGACCGCAGGGCCTTATGGAAACAAATTTGAGTCTAAAATGCGCGATTTTTTCAGCAGTAGAGACTTT
TTGCTTGTCAATTCTGGTTCATCGGCTAATCTACTAATGGTAAGCACTATTTGTTCACCTGAATTAAAATCCCAAAAGGA
TACTCAGTTACAACCTTTAGAACCAGGTGATGAAGTTATTACTCCGGCTGTAACTTTTCCTACTACTTTAGCCCCTATCA
TTCAAAACCGCTTAATACCTGTTTTTGTGGATTGCGAGGTGGGCACTTACAATATTAATCCCCATCTTATTGAGGATGCT
GTTGGGCCTCGGACAAAAGCCATTTTTATTCCTCATACTGTCGGTAATCCTTGCAATATGGAGATTATTATGGATGTAGC
TAAACGTCACAATCTATGGGTATTAGAAGATAGCTGTGATGCTTTAGGGGCAACTTTTGATGGTACTTTGGTGGGTACTT
TTGGGCAAATGGCTTCCTTGAGCTTTTATCCAGCGCACCACATGACAATGGGTGAAGGAGGAGCCGTTATTGTTAATCAA
GCTAGTCTGAAAAAAACGGTACTCTCTTTACGGGACTGGGGTAGAAGTTGTTGGTGTCCTCCAGGGATATCTGATAGTTG
TAGCAAAAGGTTTAATTGGGAATTGGGCGAACTACCATTTGGGTACGATCATAAATACATTTATTCTAACATTGGCTATA
ACTTGAAAGTTACTGATATGCAGGCGGCTATTGGTATTGCTCAAAAGGAGAAGGTTGAAGGGTTCATTGAAAAAAGGCGT
CATAATTTTTGGCGACTGTATGAAGGCTTAAAATCTCTCGAAGAGTACCTAATTTTACCTAAAATTGATTCTAGGGCTAA
CCCTTCACCATTTGGTTTTCCTATTACTGTGAAGGAAGGAATAAATCGTCGCGAGCTAGTTCAACATTTGGAAGCTCATC
AGATTGAAACTAGGTTGGTTTTTGGAGGTAATATACTAAAACAACCTGGATTTATGAATATTGAACGTAGAGTTCACGGT
ACTTTGGAAGAATCAGATATAATTATGAATCGCACGCTTTTTACTGGTGTGTTTCCTGGATTAACTGATGAAATGATAGA
TTATGTCATTGAGCAATTTACTGTTTTCTTTAAAAAAGATCCTGTTAATTCATCGGTTACTCTTTTGTCATAA

Upstream 100 bases:

>100_bases
GGGAATGAGATATAAAAGTAAACATTTCCTCGGGCTTGTTATAAGCTCACAATCTGCCAATTATTTTTGTTGACTTGAAT
ACAATTTTAGGAAAAAAACT

Downstream 100 bases:

>100_bases
ATTTTCAACATAATAGAAATAATGGTAAATACTATCCAAACAGTTGTCGAGAAAGATTTAGAGTACATCTGCACTCTTCT
TAAGGAAGAGATGTCTTGCT

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MEAENLKVQILELVKKYYQTAHQKSGFEPGKSRINYSGRVYDDQELVNLVDSSLDFWLTAGPYGNKFESKMRDFFSSRDF
LLVNSGSSANLLMVSTICSPELKSQKDTQLQPLEPGDEVITPAVTFPTTLAPIIQNRLIPVFVDCEVGTYNINPHLIEDA
VGPRTKAIFIPHTVGNPCNMEIIMDVAKRHNLWVLEDSCDALGATFDGTLVGTFGQMASLSFYPAHHMTMGEGGAVIVNQ
ASLKKTVLSLRDWGRSCWCPPGISDSCSKRFNWELGELPFGYDHKYIYSNIGYNLKVTDMQAAIGIAQKEKVEGFIEKRR
HNFWRLYEGLKSLEEYLILPKIDSRANPSPFGFPITVKEGINRRELVQHLEAHQIETRLVFGGNILKQPGFMNIERRVHG
TLEESDIIMNRTLFTGVFPGLTDEMIDYVIEQFTVFFKKDPVNSSVTLLS

Sequences:

>Translated_450_residues
MEAENLKVQILELVKKYYQTAHQKSGFEPGKSRINYSGRVYDDQELVNLVDSSLDFWLTAGPYGNKFESKMRDFFSSRDF
LLVNSGSSANLLMVSTICSPELKSQKDTQLQPLEPGDEVITPAVTFPTTLAPIIQNRLIPVFVDCEVGTYNINPHLIEDA
VGPRTKAIFIPHTVGNPCNMEIIMDVAKRHNLWVLEDSCDALGATFDGTLVGTFGQMASLSFYPAHHMTMGEGGAVIVNQ
ASLKKTVLSLRDWGRSCWCPPGISDSCSKRFNWELGELPFGYDHKYIYSNIGYNLKVTDMQAAIGIAQKEKVEGFIEKRR
HNFWRLYEGLKSLEEYLILPKIDSRANPSPFGFPITVKEGINRRELVQHLEAHQIETRLVFGGNILKQPGFMNIERRVHG
TLEESDIIMNRTLFTGVFPGLTDEMIDYVIEQFTVFFKKDPVNSSVTLLS
>Mature_450_residues
MEAENLKVQILELVKKYYQTAHQKSGFEPGKSRINYSGRVYDDQELVNLVDSSLDFWLTAGPYGNKFESKMRDFFSSRDF
LLVNSGSSANLLMVSTICSPELKSQKDTQLQPLEPGDEVITPAVTFPTTLAPIIQNRLIPVFVDCEVGTYNINPHLIEDA
VGPRTKAIFIPHTVGNPCNMEIIMDVAKRHNLWVLEDSCDALGATFDGTLVGTFGQMASLSFYPAHHMTMGEGGAVIVNQ
ASLKKTVLSLRDWGRSCWCPPGISDSCSKRFNWELGELPFGYDHKYIYSNIGYNLKVTDMQAAIGIAQKEKVEGFIEKRR
HNFWRLYEGLKSLEEYLILPKIDSRANPSPFGFPITVKEGINRRELVQHLEAHQIETRLVFGGNILKQPGFMNIERRVHG
TLEESDIIMNRTLFTGVFPGLTDEMIDYVIEQFTVFFKKDPVNSSVTLLS

Specific function: Involved In Eca Elongation. [C]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=293, Percent_Identity=30.0341296928328, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI145693159, Length=277, Percent_Identity=28.5198555956679, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 50753; Mature: 50753

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAENLKVQILELVKKYYQTAHQKSGFEPGKSRINYSGRVYDDQELVNLVDSSLDFWLTA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEECHHHHHHHHHCCCCEEEEE
GPYGNKFESKMRDFFSSRDFLLVNSGSSANLLMVSTICSPELKSQKDTQLQPLEPGDEVI
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
TPAVTFPTTLAPIIQNRLIPVFVDCEVGTYNINPHLIEDAVGPRTKAIFIPHTVGNPCNM
CCCCCCCHHHHHHHHCCCEEEEEEEECCEEECCCHHHHHCCCCCCEEEEEECCCCCCCCH
EIIMDVAKRHNLWVLEDSCDALGATFDGTLVGTFGQMASLSFYPAHHMTMGEGGAVIVNQ
HHHHHHHHHCCEEEEECCCCCCCCCCCCEEEECCHHHHCEEECCCCCEEECCCCEEEEEC
ASLKKTVLSLRDWGRSCWCPPGISDSCSKRFNWELGELPFGYDHKYIYSNIGYNLKVTDM
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEECH
QAAIGIAQKEKVEGFIEKRRHNFWRLYEGLKSLEEYLILPKIDSRANPSPFGFPITVKEG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEHHHC
INRRELVQHLEAHQIETRLVFGGNILKQPGFMNIERRVHGTLEESDIIMNRTLFTGVFPG
CCHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHHHHHCCCC
LTDEMIDYVIEQFTVFFKKDPVNSSVTLLS
CHHHHHHHHHHHHHEEEECCCCCCCEEEEC
>Mature Secondary Structure
MEAENLKVQILELVKKYYQTAHQKSGFEPGKSRINYSGRVYDDQELVNLVDSSLDFWLTA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEECHHHHHHHHHCCCCEEEEE
GPYGNKFESKMRDFFSSRDFLLVNSGSSANLLMVSTICSPELKSQKDTQLQPLEPGDEVI
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
TPAVTFPTTLAPIIQNRLIPVFVDCEVGTYNINPHLIEDAVGPRTKAIFIPHTVGNPCNM
CCCCCCCHHHHHHHHCCCEEEEEEEECCEEECCCHHHHHCCCCCCEEEEEECCCCCCCCH
EIIMDVAKRHNLWVLEDSCDALGATFDGTLVGTFGQMASLSFYPAHHMTMGEGGAVIVNQ
HHHHHHHHHCCEEEEECCCCCCCCCCCCEEEECCHHHHCEEECCCCCEEECCCCEEEEEC
ASLKKTVLSLRDWGRSCWCPPGISDSCSKRFNWELGELPFGYDHKYIYSNIGYNLKVTDM
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEECH
QAAIGIAQKEKVEGFIEKRRHNFWRLYEGLKSLEEYLILPKIDSRANPSPFGFPITVKEG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEHHHC
INRRELVQHLEAHQIETRLVFGGNILKQPGFMNIERRVHGTLEESDIIMNRTLFTGVFPG
CCHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHHHHHCCCC
LTDEMIDYVIEQFTVFFKKDPVNSSVTLLS
CHHHHHHHHHHHHHEEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]