Click here to switch to the map view.

The map label for this gene is aroE [H]

Identifier: 113475829

GI number: 113475829

Start: 3414061

End: 3414966

Strand: Direct

Name: aroE [H]

Synonym: Tery_2187

Alternate gene names: 113475829

Gene position: 3414061-3414966 (Clockwise)

Preceding gene: 113475826

Following gene: 113475830

Centisome position: 44.05

GC content: 37.42

Gene sequence:

>906_bases
ATGATTACAAGTAAAACAAAATTATTAGGAGTCATTGGTTATCCTCTTGAACATTCTCTGTCTCCTTTAATGCACAATGC
TGCAATTCAAGCAATAAATGCTCAACAAGCTCAACAAAATTTAATTGATTATATATATCTACCTTTCCCTATTAAACCAG
AAAATTTAAACGCAGCTATTACGGGATTTTCTGCTATTGGCGTTCAGGGTTTTAATATTACTATCCCTCATAAACAAACA
ATAATGCCACTATTATCAGAAGTTTCCGATATCGCTCAGGCGGTGGGAGCAGTTAATACTGTTTATAAAACACATTCTCA
TAGAACACATCAAGGATGGACGGGGACAAATACAGATGTGGCAGGATTTCTGGCCCCACTACAAACCTATCGTTGGGATA
TGCATCAAAAAGTAGCAGTAATTTTAGGTAACGGTGGTGCTTCTCGTGCAGTTGTTGCGGGTTGCATTCAGTTAGGTTTT
GCAGAAATTCATATTATTGGTCGGTCAATAGAAAAATTAACTGCTTTTCAGCAAAGTTGGCTTAATTCTCCTCTAGCCAT
AAGTTTGAAAATACATAAATGGGATAAACTGTCAAGCTTAATTTCACAGGCAGATTTGTTAGTTAACACAACTCCTATAG
GAATGTACCCAAACATTCAGGAGTCTCCAGTAGATGAGAAGGTTTTTGACAAATTGTCGCCAGGGGCGATCGTCTATGAC
TTAATTTATATTCCTAACCCTACTAAGTTTCTTCAGCAAGCTCAGGAGAGGGGAGCGATCGCTATTGACGGTTTAGAAAT
GTTAGTTCAACAAGGAGCTGCTGCCTTAGAACTATGGTTACAACAGTCTGTACCAGTGGATGTTATGCGCTATTCTTTGC
ATAAACATTTAGGATTAAATAAATAA

Upstream 100 bases:

>100_bases
CAGAATTGTTTTACTCTAGCGCTATAGTTTTTTTGAATTTTCAAAATATCAACAAATATACTAAAATATAGCAAATACCA
GTTTAAATTTATTTTCGCAA

Downstream 100 bases:

>100_bases
TTAGGACTGGTTCAAAAAAACTATAAGTGGACATATAAATTTCTATTTATACCAGTTTCAGAGGGGCGTAAAGTAAAAAA
AACTTGATGACTTTAGACTT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MITSKTKLLGVIGYPLEHSLSPLMHNAAIQAINAQQAQQNLIDYIYLPFPIKPENLNAAITGFSAIGVQGFNITIPHKQT
IMPLLSEVSDIAQAVGAVNTVYKTHSHRTHQGWTGTNTDVAGFLAPLQTYRWDMHQKVAVILGNGGASRAVVAGCIQLGF
AEIHIIGRSIEKLTAFQQSWLNSPLAISLKIHKWDKLSSLISQADLLVNTTPIGMYPNIQESPVDEKVFDKLSPGAIVYD
LIYIPNPTKFLQQAQERGAIAIDGLEMLVQQGAAALELWLQQSVPVDVMRYSLHKHLGLNK

Sequences:

>Translated_301_residues
MITSKTKLLGVIGYPLEHSLSPLMHNAAIQAINAQQAQQNLIDYIYLPFPIKPENLNAAITGFSAIGVQGFNITIPHKQT
IMPLLSEVSDIAQAVGAVNTVYKTHSHRTHQGWTGTNTDVAGFLAPLQTYRWDMHQKVAVILGNGGASRAVVAGCIQLGF
AEIHIIGRSIEKLTAFQQSWLNSPLAISLKIHKWDKLSSLISQADLLVNTTPIGMYPNIQESPVDEKVFDKLSPGAIVYD
LIYIPNPTKFLQQAQERGAIAIDGLEMLVQQGAAALELWLQQSVPVDVMRYSLHKHLGLNK
>Mature_301_residues
MITSKTKLLGVIGYPLEHSLSPLMHNAAIQAINAQQAQQNLIDYIYLPFPIKPENLNAAITGFSAIGVQGFNITIPHKQT
IMPLLSEVSDIAQAVGAVNTVYKTHSHRTHQGWTGTNTDVAGFLAPLQTYRWDMHQKVAVILGNGGASRAVVAGCIQLGF
AEIHIIGRSIEKLTAFQQSWLNSPLAISLKIHKWDKLSSLISQADLLVNTTPIGMYPNIQESPVDEKVFDKLSPGAIVYD
LIYIPNPTKFLQQAQERGAIAIDGLEMLVQQGAAALELWLQQSVPVDVMRYSLHKHLGLNK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=295, Percent_Identity=32.2033898305085, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789675, Length=270, Percent_Identity=28.8888888888889, Blast_Score=95, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=298, Percent_Identity=26.8456375838926, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 33001; Mature: 33001

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSKTKLLGVIGYPLEHSLSPLMHNAAIQAINAQQAQQNLIDYIYLPFPIKPENLNAAI
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEE
TGFSAIGVQGFNITIPHKQTIMPLLSEVSDIAQAVGAVNTVYKTHSHRTHQGWTGTNTDV
ECHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AGFLAPLQTYRWDMHQKVAVILGNGGASRAVVAGCIQLGFAEIHIIGRSIEKLTAFQQSW
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHH
LNSPLAISLKIHKWDKLSSLISQADLLVNTTPIGMYPNIQESPVDEKVFDKLSPGAIVYD
CCCCEEEEEEEECHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHCCCCEEEEE
LIYIPNPTKFLQQAQERGAIAIDGLEMLVQQGAAALELWLQQSVPVDVMRYSLHKHLGLN
EEECCCHHHHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
K
C
>Mature Secondary Structure
MITSKTKLLGVIGYPLEHSLSPLMHNAAIQAINAQQAQQNLIDYIYLPFPIKPENLNAAI
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEE
TGFSAIGVQGFNITIPHKQTIMPLLSEVSDIAQAVGAVNTVYKTHSHRTHQGWTGTNTDV
ECHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AGFLAPLQTYRWDMHQKVAVILGNGGASRAVVAGCIQLGFAEIHIIGRSIEKLTAFQQSW
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHH
LNSPLAISLKIHKWDKLSSLISQADLLVNTTPIGMYPNIQESPVDEKVFDKLSPGAIVYD
CCCCEEEEEEEECHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHCCCCEEEEE
LIYIPNPTKFLQQAQERGAIAIDGLEMLVQQGAAALELWLQQSVPVDVMRYSLHKHLGLN
EEECCCHHHHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA