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The map label for this gene is mtnA

Identifier: 113475731

GI number: 113475731

Start: 3246669

End: 3247730

Strand: Direct

Name: mtnA

Synonym: Tery_2078

Alternate gene names: 113475731

Gene position: 3246669-3247730 (Clockwise)

Preceding gene: 113475719

Following gene: 113475733

Centisome position: 41.89

GC content: 37.76

Gene sequence:

>1062_bases
ATGATATATAAATTCAGAAAAGTAAACCCCATTACTTGGAAAAATGACCATGTTGTATTAATTGATCAAACTTGCTTACC
AGAAGAATATAAAACAGTCGAAATTAGCAGCTATGAAGAAATGGCAGTAGCTATCAAAACAATGATAGTTCGTGGAGCAC
CAGCCATCGGTGTATCAGTAGCTTATGGAATGTATTTAGGAGCAAGAGAAACTGTCACAAATGATAGAAATGAATTCTTA
AAACAGCTAGAAGAAATAGCTGTAATTTTCCGAAGAACTCGCCCAACTGCTGTTAATTTATTTTGGGCAATAGAGCGAAT
ATTAAAAGTAGCAAATAAAACTAATGGAACTGTAAAAGAAATTCAAGAAGCGGTATTAGAAACTGCTAAAAAAATTCATC
AAGAAGACTTAGAAACCTGTAAAAATATAGGCGATCGCGCAGTTGAAATTTTACCAACTAAACCCGAAAAATTGAACATA
TTAACCCACTGTAATGCAGGAGCTTTAGCAACAGCAGGCTATGGTACAGCATTAGGAGTTATTCGTTCCGCCTGGCGAGA
TGGAAGGTTAGGCAAAGTCTACGCTGATGAAACTCGTCCCCGTCTCCAAGGAGCAAAACTTACCACCTGGGAATGTGTCC
AAGAAAACATACCCGTCACCCTAATTAGCGATAACATGGCAGCCCACTGTATGAAACAAGGCTTAATTCATGCTGTAGTA
GTAGGAGCTGACAGAATAGCAGCAAATGGAGACACTGCCAATAAAATTGGTACTTATAGCCTAGCTATTGTCTCTCAAGC
ACATAATATTCCCTTGTATGTAGCTGCACCCCTATCAACTATAGACTTTAAAATCTCTGATGGTAGTGAAATACCCATAG
AAGAAAGGGATACAAAAGAAATATATCAAGTAGGAGAAACACGCATTTGTCCAAAACAAGTAGAATTTTATAACCCGGCA
TTTGATGTTACACCTGCAGAACTAATTACAGGAATAATGACAGAACATGGTACAGTTCTCCCAGGAGAACTAGAACAATT
TCGGGTCAAGCAGTTAGTTTAA

Upstream 100 bases:

>100_bases
AGAAAACCTAAAACGGAAGAAAACCTAAAACCATAATAAAATCTAAAACCTAACACCAGGGTGATATATTGTATTTACGT
TCATCAAAAAACCATGGAAA

Downstream 100 bases:

>100_bases
TTTAATAAAAACATTAACTAACAACTGAAGCGGCCAGGGAAACAACCTTAACCAACAGTTGGAGCCATATCTATCTCAAC
TAACCCTTCTAATTCTGTAA

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIYKFRKVNPITWKNDHVVLIDQTCLPEEYKTVEISSYEEMAVAIKTMIVRGAPAIGVSVAYGMYLGARETVTNDRNEFL
KQLEEIAVIFRRTRPTAVNLFWAIERILKVANKTNGTVKEIQEAVLETAKKIHQEDLETCKNIGDRAVEILPTKPEKLNI
LTHCNAGALATAGYGTALGVIRSAWRDGRLGKVYADETRPRLQGAKLTTWECVQENIPVTLISDNMAAHCMKQGLIHAVV
VGADRIAANGDTANKIGTYSLAIVSQAHNIPLYVAAPLSTIDFKISDGSEIPIEERDTKEIYQVGETRICPKQVEFYNPA
FDVTPAELITGIMTEHGTVLPGELEQFRVKQLV

Sequences:

>Translated_353_residues
MIYKFRKVNPITWKNDHVVLIDQTCLPEEYKTVEISSYEEMAVAIKTMIVRGAPAIGVSVAYGMYLGARETVTNDRNEFL
KQLEEIAVIFRRTRPTAVNLFWAIERILKVANKTNGTVKEIQEAVLETAKKIHQEDLETCKNIGDRAVEILPTKPEKLNI
LTHCNAGALATAGYGTALGVIRSAWRDGRLGKVYADETRPRLQGAKLTTWECVQENIPVTLISDNMAAHCMKQGLIHAVV
VGADRIAANGDTANKIGTYSLAIVSQAHNIPLYVAAPLSTIDFKISDGSEIPIEERDTKEIYQVGETRICPKQVEFYNPA
FDVTPAELITGIMTEHGTVLPGELEQFRVKQLV
>Mature_353_residues
MIYKFRKVNPITWKNDHVVLIDQTCLPEEYKTVEISSYEEMAVAIKTMIVRGAPAIGVSVAYGMYLGARETVTNDRNEFL
KQLEEIAVIFRRTRPTAVNLFWAIERILKVANKTNGTVKEIQEAVLETAKKIHQEDLETCKNIGDRAVEILPTKPEKLNI
LTHCNAGALATAGYGTALGVIRSAWRDGRLGKVYADETRPRLQGAKLTTWECVQENIPVTLISDNMAAHCMKQGLIHAVV
VGADRIAANGDTANKIGTYSLAIVSQAHNIPLYVAAPLSTIDFKISDGSEIPIEERDTKEIYQVGETRICPKQVEFYNPA
FDVTPAELITGIMTEHGTVLPGELEQFRVKQLV

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily

Homologues:

Organism=Homo sapiens, GI72534748, Length=347, Percent_Identity=43.2276657060519, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI23943880, Length=339, Percent_Identity=37.7581120943953, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4503503, Length=286, Percent_Identity=25.1748251748252, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557462, Length=359, Percent_Identity=36.7688022284123, Blast_Score=215, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17557123, Length=184, Percent_Identity=29.8913043478261, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325375, Length=408, Percent_Identity=34.0686274509804, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI21357667, Length=360, Percent_Identity=39.1666666666667, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24651647, Length=360, Percent_Identity=39.1666666666667, Blast_Score=250, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNA_TRIEI (Q113K5)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721792.1
- ProteinModelPortal:   Q113K5
- SMR:   Q113K5
- STRING:   Q113K5
- GeneID:   4245726
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2078
- NMPDR:   fig|203124.1.peg.2191
- eggNOG:   COG0182
- HOGENOM:   HBG682649
- OMA:   RPRNQGA
- PhylomeDB:   Q113K5
- ProtClustDB:   PRK05720
- BioCyc:   TERY203124:TERY_2078-MONOMER
- HAMAP:   MF_01678
- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559
- PANTHER:   PTHR10233
- TIGRFAMs:   TIGR00524
- TIGRFAMs:   TIGR00512

Pfam domain/function: PF01008 IF-2B

EC number: =5.3.1.23

Molecular weight: Translated: 39181; Mature: 39181

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: ACT_SITE 244-244 BINDING 94-94 BINDING 203-203

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYKFRKVNPITWKNDHVVLIDQTCLPEEYKTVEISSYEEMAVAIKTMIVRGAPAIGVSV
CCEEEECCCCCEECCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHH
AYGMYLGARETVTNDRNEFLKQLEEIAVIFRRTRPTAVNLFWAIERILKVANKTNGTVKE
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
IQEAVLETAKKIHQEDLETCKNIGDRAVEILPTKPEKLNILTHCNAGALATAGYGTALGV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCEEECCCHHHHHH
IRSAWRDGRLGKVYADETRPRLQGAKLTTWECVQENIPVTLISDNMAAHCMKQGLIHAVV
HHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEE
VGADRIAANGDTANKIGTYSLAIVSQAHNIPLYVAAPLSTIDFKISDGSEIPIEERDTKE
ECCCCEECCCCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEEEECCCCCCCCCCCCHHH
IYQVGETRICPKQVEFYNPAFDVTPAELITGIMTEHGTVLPGELEQFRVKQLV
HHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIYKFRKVNPITWKNDHVVLIDQTCLPEEYKTVEISSYEEMAVAIKTMIVRGAPAIGVSV
CCEEEECCCCCEECCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHH
AYGMYLGARETVTNDRNEFLKQLEEIAVIFRRTRPTAVNLFWAIERILKVANKTNGTVKE
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
IQEAVLETAKKIHQEDLETCKNIGDRAVEILPTKPEKLNILTHCNAGALATAGYGTALGV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCEEECCCHHHHHH
IRSAWRDGRLGKVYADETRPRLQGAKLTTWECVQENIPVTLISDNMAAHCMKQGLIHAVV
HHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEE
VGADRIAANGDTANKIGTYSLAIVSQAHNIPLYVAAPLSTIDFKISDGSEIPIEERDTKE
ECCCCEECCCCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEEEECCCCCCCCCCCCHHH
IYQVGETRICPKQVEFYNPAFDVTPAELITGIMTEHGTVLPGELEQFRVKQLV
HHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA