Click here to switch to the map view.

The map label for this gene is trxA [H]

Identifier: 113475671

GI number: 113475671

Start: 3132658

End: 3133047

Strand: Direct

Name: trxA [H]

Synonym: Tery_2011

Alternate gene names: 113475671

Gene position: 3132658-3133047 (Clockwise)

Preceding gene: 113475670

Following gene: 113475673

Centisome position: 40.42

GC content: 36.67

Gene sequence:

>390_bases
ATGATGATTTTGTCAGTTAACGAAAAGACTTTTAAAAAAGAGGTTTTGGAATCTTCTCAACCTGTTTTAGTTTATTTTTG
GGCCCCTTGGTGTGGCTTGTGTAAAATGATTGTCCCCCAATTAGTTAAATTTCAATCTGAGTGGAATTGCCATTTAAAGC
TGGTAGGGGTGAATGCTGACAAAAGTTTAAAACTTGCTAGCACCTATCAACTCCAAACTTTGCCTACTTTGATTCTCTTT
GTTAATGGGCAAATAGTTAATCGATTAGGTTATTTTCAGGCACGAGAAGATTTCCAGCGAACATTGGATGCTTTTATTTC
AACTTTAGTTAAAGACCCACCCTCTCAGCCAAGAGAGCATCGGAATGAAAAACAATCAATATTGTGGTGA

Upstream 100 bases:

>100_bases
TATTCTGGCAAGCTCATCCTTTACTAATCCGTGCAACTGGGAACATAGACTGGTAGCATAATCCCAGGATATAAAAAATT
TAATTTAAATAGATTTAAAC

Downstream 100 bases:

>100_bases
AATTAAATTTTTTACTAACCTGTCCGGATATATATAAAAATACAGGTTAAGTGAGGAAGAATACCAATTTTGGGAACACT
GCACCAAAGATTGGTATCTC

Product: thioredoxin domain-containing protein

Products: NA

Alternate protein names: Trx-1; Thioredoxin-M [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MMILSVNEKTFKKEVLESSQPVLVYFWAPWCGLCKMIVPQLVKFQSEWNCHLKLVGVNADKSLKLASTYQLQTLPTLILF
VNGQIVNRLGYFQAREDFQRTLDAFISTLVKDPPSQPREHRNEKQSILW

Sequences:

>Translated_129_residues
MMILSVNEKTFKKEVLESSQPVLVYFWAPWCGLCKMIVPQLVKFQSEWNCHLKLVGVNADKSLKLASTYQLQTLPTLILF
VNGQIVNRLGYFQAREDFQRTLDAFISTLVKDPPSQPREHRNEKQSILW
>Mature_129_residues
MMILSVNEKTFKKEVLESSQPVLVYFWAPWCGLCKMIVPQLVKFQSEWNCHLKLVGVNADKSLKLASTYQLQTLPTLILF
VNGQIVNRLGYFQAREDFQRTLDAFISTLVKDPPSQPREHRNEKQSILW

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=84, Percent_Identity=36.9047619047619, Blast_Score=73, Evalue=5e-15,
Organism=Escherichia coli, GI1788936, Length=87, Percent_Identity=32.183908045977, Blast_Score=67, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573567, Length=112, Percent_Identity=33.0357142857143, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 15000; Mature: 15000

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILSVNEKTFKKEVLESSQPVLVYFWAPWCGLCKMIVPQLVKFQSEWNCHLKLVGVNAD
CEEEECCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
KSLKLASTYQLQTLPTLILFVNGQIVNRLGYFQAREDFQRTLDAFISTLVKDPPSQPREH
CCEEEHHHHHHHHHHEEEHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RNEKQSILW
CCHHHCCCC
>Mature Secondary Structure
MMILSVNEKTFKKEVLESSQPVLVYFWAPWCGLCKMIVPQLVKFQSEWNCHLKLVGVNAD
CEEEECCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
KSLKLASTYQLQTLPTLILFVNGQIVNRLGYFQAREDFQRTLDAFISTLVKDPPSQPREH
CCEEEHHHHHHHHHHEEEHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RNEKQSILW
CCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2492995 [H]