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The map label for this gene is aapQ [H]

Identifier: 113475660

GI number: 113475660

Start: 3114067

End: 3115233

Strand: Direct

Name: aapQ [H]

Synonym: Tery_1999

Alternate gene names: 113475660

Gene position: 3114067-3115233 (Clockwise)

Preceding gene: 113475659

Following gene: 113475661

Centisome position: 40.18

GC content: 32.82

Gene sequence:

>1167_bases
ATGATTGACGACAAAAATCAAAAAATTCCCCTATGGCGAGATGATAGATTTTGGCGTGTTGCCTTGCAAGTTTTAGCTAT
CATAATTTTTGTTGTGGTTGTATTTATAATGATTAGTAACCTCAGCCGCAATTTAGCACAACAAGGCACAAGGTTTGGCT
TCAGTTTTCTAGACAATGAAGCTGCATTTAGTATTAGTGAAAGTTTGATTCCTTACGAAGCAAGTGACCCCTATATTCAA
GTATTATTAGCAGGTTTATTTAATTCTCTGCGAGTAATGATTTTAGGAATTTTCTTGACAACAATACTGGGAATAGTAGC
AGGTATCGCTAGTTTTTCTGAGAATTGGTTACTCCGGAATTTGAATCGAGTTTATGTGGAAGTTGTTAGAAATACTCCCC
TATTATTACAGTTATTTTTTTGGTATTTTGCCGTTTTTTTCAATCTACCATTACCTCAAGAAAAATTAGAATTACCAGGA
CCAATATTTATGAGTAAACGAGGAATAGCTATTCCTTGGCCGGAAAATACTGTTAATGTTTGGTTATGGTTAATAGTTTT
ATTTTTAGGAGCGATCGCTGCTATATTTATTTGGCAATGGCGGAATAAATTAATGACAGAAAAAGCAGCATCTGGTCAAC
CACAACTTATAGCTATAATTACCATAGGAATTATGGAGCTATTAATTATTATATTTGCTTTGGGTTGGCAAGCACCTATA
GCAACAGAAACAGGAGGTACAAAAGGAGGATTAAATTTAACACTAGAAATCTCAGCTTTACTAGTAGGATTAGTATTTTA
TACGGGTGCTTTTATTGCTGAAATTGTTCGTTCTGGGATTCAAGCAGTGCCAAAAGGGCAATGGGAAGCAGCTAAATCTT
TAGGATTAAAGCCTGGTTTAGTAATGAGGTTAGTTATTTTTCCTCAAGCATTACGGGTTATGATTCCATCATTAAATAGT
CAATATATGAATTTAGCTAAAAACTCTAGTTTAGCAATAGCTATTGGTTATCCAGATTTATATGCTGTAGCTAATACTAC
TTATAATCAAACAGGTCGTCCTATAGAAGTATTTATTTTAATTATGGTGGTTTATCTTTCCATAAATTTGATAATTTCTC
TATCTATGAATTTTTTGAATAAAAGTGTTCAATTAAAAGAAAGATAA

Upstream 100 bases:

>100_bases
CTCTTGACTTATAAAAAGAGTAATGCATAGCTTAGATATAATGAGAAATATTTACTATCTACACTACTTTTTGTTTAACT
ATTTATTATATCCCTAAAAG

Downstream 100 bases:

>100_bases
TCAAATTAAAAAGTCAATTAATCTATAATCTTTCTAAGGGCTATCCATAATCAGGAATTCCTAAAACTATTTTATGATAG
GCAGATTGGTGGTGAGTATA

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIDDKNQKIPLWRDDRFWRVALQVLAIIIFVVVVFIMISNLSRNLAQQGTRFGFSFLDNEAAFSISESLIPYEASDPYIQ
VLLAGLFNSLRVMILGIFLTTILGIVAGIASFSENWLLRNLNRVYVEVVRNTPLLLQLFFWYFAVFFNLPLPQEKLELPG
PIFMSKRGIAIPWPENTVNVWLWLIVLFLGAIAAIFIWQWRNKLMTEKAASGQPQLIAIITIGIMELLIIIFALGWQAPI
ATETGGTKGGLNLTLEISALLVGLVFYTGAFIAEIVRSGIQAVPKGQWEAAKSLGLKPGLVMRLVIFPQALRVMIPSLNS
QYMNLAKNSSLAIAIGYPDLYAVANTTYNQTGRPIEVFILIMVVYLSINLIISLSMNFLNKSVQLKER

Sequences:

>Translated_388_residues
MIDDKNQKIPLWRDDRFWRVALQVLAIIIFVVVVFIMISNLSRNLAQQGTRFGFSFLDNEAAFSISESLIPYEASDPYIQ
VLLAGLFNSLRVMILGIFLTTILGIVAGIASFSENWLLRNLNRVYVEVVRNTPLLLQLFFWYFAVFFNLPLPQEKLELPG
PIFMSKRGIAIPWPENTVNVWLWLIVLFLGAIAAIFIWQWRNKLMTEKAASGQPQLIAIITIGIMELLIIIFALGWQAPI
ATETGGTKGGLNLTLEISALLVGLVFYTGAFIAEIVRSGIQAVPKGQWEAAKSLGLKPGLVMRLVIFPQALRVMIPSLNS
QYMNLAKNSSLAIAIGYPDLYAVANTTYNQTGRPIEVFILIMVVYLSINLIISLSMNFLNKSVQLKER
>Mature_388_residues
MIDDKNQKIPLWRDDRFWRVALQVLAIIIFVVVVFIMISNLSRNLAQQGTRFGFSFLDNEAAFSISESLIPYEASDPYIQ
VLLAGLFNSLRVMILGIFLTTILGIVAGIASFSENWLLRNLNRVYVEVVRNTPLLLQLFFWYFAVFFNLPLPQEKLELPG
PIFMSKRGIAIPWPENTVNVWLWLIVLFLGAIAAIFIWQWRNKLMTEKAASGQPQLIAIITIGIMELLIIIFALGWQAPI
ATETGGTKGGLNLTLEISALLVGLVFYTGAFIAEIVRSGIQAVPKGQWEAAKSLGLKPGLVMRLVIFPQALRVMIPSLNS
QYMNLAKNSSLAIAIGYPDLYAVANTTYNQTGRPIEVFILIMVVYLSINLIISLSMNFLNKSVQLKER

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=359, Percent_Identity=44.0111420612813, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1788226, Length=135, Percent_Identity=35.5555555555556, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786874, Length=134, Percent_Identity=36.5671641791045, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87082239, Length=124, Percent_Identity=38.7096774193548, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786873, Length=121, Percent_Identity=33.0578512396694, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787030, Length=128, Percent_Identity=33.59375, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788645, Length=125, Percent_Identity=29.6, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787087, Length=119, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43501; Mature: 43501

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDKNQKIPLWRDDRFWRVALQVLAIIIFVVVVFIMISNLSRNLAQQGTRFGFSFLDNE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHCCC
AAFSISESLIPYEASDPYIQVLLAGLFNSLRVMILGIFLTTILGIVAGIASFSENWLLRN
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRVYVEVVRNTPLLLQLFFWYFAVFFNLPLPQEKLELPGPIFMSKRGIAIPWPENTVNV
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCCCEECCCCCCHHHH
WLWLIVLFLGAIAAIFIWQWRNKLMTEKAASGQPQLIAIITIGIMELLIIIFALGWQAPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCC
ATETGGTKGGLNLTLEISALLVGLVFYTGAFIAEIVRSGIQAVPKGQWEAAKSLGLKPGL
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHH
VMRLVIFPQALRVMIPSLNSQYMNLAKNSSLAIAIGYPDLYAVANTTYNQTGRPIEVFIL
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCHHHHHHH
IMVVYLSINLIISLSMNFLNKSVQLKER
HHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIDDKNQKIPLWRDDRFWRVALQVLAIIIFVVVVFIMISNLSRNLAQQGTRFGFSFLDNE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHCCC
AAFSISESLIPYEASDPYIQVLLAGLFNSLRVMILGIFLTTILGIVAGIASFSENWLLRN
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRVYVEVVRNTPLLLQLFFWYFAVFFNLPLPQEKLELPGPIFMSKRGIAIPWPENTVNV
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCCCEECCCCCCHHHH
WLWLIVLFLGAIAAIFIWQWRNKLMTEKAASGQPQLIAIITIGIMELLIIIFALGWQAPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCC
ATETGGTKGGLNLTLEISALLVGLVFYTGAFIAEIVRSGIQAVPKGQWEAAKSLGLKPGL
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHH
VMRLVIFPQALRVMIPSLNSQYMNLAKNSSLAIAIGYPDLYAVANTTYNQTGRPIEVFIL
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCHHHHHHH
IMVVYLSINLIISLSMNFLNKSVQLKER
HHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]