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The map label for this gene is fabH

Identifier: 113475486

GI number: 113475486

Start: 2773777

End: 2774766

Strand: Direct

Name: fabH

Synonym: Tery_1817

Alternate gene names: 113475486

Gene position: 2773777-2774766 (Clockwise)

Preceding gene: 113475485

Following gene: 113475487

Centisome position: 35.79

GC content: 38.08

Gene sequence:

>990_bases
ATGACAAATATAGGCGTTTCTATAATTGGAAGTGGTTCTGCAATACCAAAAACATCTCTAGATAATCAACAATTATCCCA
AATAGTAGAGACTTCTGACGAATGGATCATTTCTCGCACTGGAATTAATAAGCGACAGCTAGTAGATACAACAGAATCAT
TATGTAGCCTTGCTACTCAAGCATCTCTAGCAGCTCTTAACCAAGCAAATATTACTCCTAAAGATATTGACCTAATTATT
CTGGCTACATCTACTCCTGATGACTTATTTGGTACTGCATGTAAAATTCAATGGGAGTTGGGCGCACAGAAAGCAGTTGC
TTTTGACATAACTGTGGCTTGTTCTGGTTTTCTCTTTGCTCTGGTTACAGGAGCGCAATTTATTCGTAATGGAGTTTATC
AAAATGTTTTGTTAATTGGGGCAGATATTCTCTCGCGTTGGGTAGACTGGGAAGACCGACGGACTTGTGTTTTATTTGGA
GATGGGGCAGGGGCAGTACTTTTACAAGCTTCAGAAAGCGATCGCCTGCTGGGTTTTGAACTTGGTAGTGATGGTAGTCA
AAATAGCTGTTTAAGTCTTTCTTACCAACCCCAAGAAAAGAGAATAATTGAGGGAGTAACTGTTAGTCAAGGTACTTATC
AACCAATAGCTATGAATGGTAAAGAAGTCTATCGTTTTGTAGTACAAAAAGTACCGGAAGCTATAGAAAAAGCTTTATTA
AAAGCTAATATTGATATTGATAAACTTGACTGGTTGCTATTACACCAAGCTAACCAAAGAATCCTTGATGCTGTTGCTAA
TAGATTGAATATTCCACCAGAAAAAGTTATTAGTAATCTACGAAATTATGGCAATACTTCTGCTGCTTCTATACCGCTAG
CTTTAGATGAAGTTGTTAGGGAAGGACTTGTTAAATCAGGAGACATTATTGCTGCTTCTGGCTTTGGGGCTGGATTAAGT
TGGGGTGCAGTAATTTTTCAATGGAACTGA

Upstream 100 bases:

>100_bases
ATCAAGAAAAGTTTAGGAATGTCGAAAGTTGTAGATTAAGTCTACATTGATATGAATAATAAACAATACTAGAAAATTAA
TAATAATTAAAAACAGATAG

Downstream 100 bases:

>100_bases
TAGGATTAATATCAAGATTTTCATCTTGCTTTTTACTTTATTCAAAATTTATACCAAAAAAATTTCTCTGAAATATCGTC
CATAAGTGGGCGAATTTTTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTNIGVSIIGSGSAIPKTSLDNQQLSQIVETSDEWIISRTGINKRQLVDTTESLCSLATQASLAALNQANITPKDIDLII
LATSTPDDLFGTACKIQWELGAQKAVAFDITVACSGFLFALVTGAQFIRNGVYQNVLLIGADILSRWVDWEDRRTCVLFG
DGAGAVLLQASESDRLLGFELGSDGSQNSCLSLSYQPQEKRIIEGVTVSQGTYQPIAMNGKEVYRFVVQKVPEAIEKALL
KANIDIDKLDWLLLHQANQRILDAVANRLNIPPEKVISNLRNYGNTSAASIPLALDEVVREGLVKSGDIIAASGFGAGLS
WGAVIFQWN

Sequences:

>Translated_329_residues
MTNIGVSIIGSGSAIPKTSLDNQQLSQIVETSDEWIISRTGINKRQLVDTTESLCSLATQASLAALNQANITPKDIDLII
LATSTPDDLFGTACKIQWELGAQKAVAFDITVACSGFLFALVTGAQFIRNGVYQNVLLIGADILSRWVDWEDRRTCVLFG
DGAGAVLLQASESDRLLGFELGSDGSQNSCLSLSYQPQEKRIIEGVTVSQGTYQPIAMNGKEVYRFVVQKVPEAIEKALL
KANIDIDKLDWLLLHQANQRILDAVANRLNIPPEKVISNLRNYGNTSAASIPLALDEVVREGLVKSGDIIAASGFGAGLS
WGAVIFQWN
>Mature_328_residues
TNIGVSIIGSGSAIPKTSLDNQQLSQIVETSDEWIISRTGINKRQLVDTTESLCSLATQASLAALNQANITPKDIDLIIL
ATSTPDDLFGTACKIQWELGAQKAVAFDITVACSGFLFALVTGAQFIRNGVYQNVLLIGADILSRWVDWEDRRTCVLFGD
GAGAVLLQASESDRLLGFELGSDGSQNSCLSLSYQPQEKRIIEGVTVSQGTYQPIAMNGKEVYRFVVQKVPEAIEKALLK
ANIDIDKLDWLLLHQANQRILDAVANRLNIPPEKVISNLRNYGNTSAASIPLALDEVVREGLVKSGDIIAASGFGAGLSW
GAVIFQWN

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=37.5776397515528, Blast_Score=242, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABH_TRIEI (Q114K0)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721547.1
- ProteinModelPortal:   Q114K0
- SMR:   Q114K0
- STRING:   Q114K0
- GeneID:   4244531
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_1817
- NMPDR:   fig|203124.1.peg.396
- eggNOG:   COG0332
- HOGENOM:   HBG649927
- OMA:   ERHVIAN
- PhylomeDB:   Q114K0
- ProtClustDB:   PRK09352
- BioCyc:   TERY203124:TERY_1817-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01815
- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- TIGRFAMs:   TIGR00747

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C; SSF53901 Thiolase-like

EC number: =2.3.1.41

Molecular weight: Translated: 35526; Mature: 35395

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: ACT_SITE 114-114 ACT_SITE 255-255 ACT_SITE 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIGVSIIGSGSAIPKTSLDNQQLSQIVETSDEWIISRTGINKRQLVDTTESLCSLATQ
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
ASLAALNQANITPKDIDLIILATSTPDDLFGTACKIQWELGAQKAVAFDITVACSGFLFA
HHHHHHHCCCCCCCCEEEEEEEECCCHHHCCCEEEEEEECCCCEEEEEEEHHHHHHHHHH
LVTGAQFIRNGVYQNVLLIGADILSRWVDWEDRRTCVLFGDGAGAVLLQASESDRLLGFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEE
LGSDGSQNSCLSLSYQPQEKRIIEGVTVSQGTYQPIAMNGKEVYRFVVQKVPEAIEKALL
ECCCCCCCCEEEEEECCCHHHHHCCEEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
KANIDIDKLDWLLLHQANQRILDAVANRLNIPPEKVISNLRNYGNTSAASIPLALDEVVR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
EGLVKSGDIIAASGFGAGLSWGAVIFQWN
HCCCCCCCEEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
TNIGVSIIGSGSAIPKTSLDNQQLSQIVETSDEWIISRTGINKRQLVDTTESLCSLATQ
CCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
ASLAALNQANITPKDIDLIILATSTPDDLFGTACKIQWELGAQKAVAFDITVACSGFLFA
HHHHHHHCCCCCCCCEEEEEEEECCCHHHCCCEEEEEEECCCCEEEEEEEHHHHHHHHHH
LVTGAQFIRNGVYQNVLLIGADILSRWVDWEDRRTCVLFGDGAGAVLLQASESDRLLGFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEE
LGSDGSQNSCLSLSYQPQEKRIIEGVTVSQGTYQPIAMNGKEVYRFVVQKVPEAIEKALL
ECCCCCCCCEEEEEECCCHHHHHCCEEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
KANIDIDKLDWLLLHQANQRILDAVANRLNIPPEKVISNLRNYGNTSAASIPLALDEVVR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
EGLVKSGDIIAASGFGAGLSWGAVIFQWN
HCCCCCCCEEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA