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The map label for this gene is napA [H]

Identifier: 113475319

GI number: 113475319

Start: 2491379

End: 2492803

Strand: Reverse

Name: napA [H]

Synonym: Tery_1631

Alternate gene names: 113475319

Gene position: 2492803-2491379 (Counterclockwise)

Preceding gene: 113475320

Following gene: 113475316

Centisome position: 32.16

GC content: 40.84

Gene sequence:

>1425_bases
ATGTTTAGTTTAATGGCAGAGTCCAATTTTTTTAGTGAAATTTTCTTATTTCCTTTATCGGGAAAAATTGCACCGATACT
AGCTACGGCCACAGAAACGGGAGCCGAACCAGAAATGGTACTAGCAGGAGTGTTGTTGAGTTTAGTGGCCATTTATATAG
CTAGTAAAGCAGGAGGAGAATTTTTTAGCTGGCTGAATTTTCCACCTGTATTAGGAGAATTGGTGGGGGGTGTAGTTATA
GGTATTTCTGCCCTACACTTGGTAATCTTTCCAGAAAGTGGGGCCGATAGTTCTTCGTCAGTAATTATTAACATTTTGGA
GGCAACAGCAGGTTTAGCTCCTGAAGCTGCTGGGGCTACATTGCAGGCTCAAAGTGAGGTACTAGATGTTCTAGCAGAAC
TGGGTGTGATCATTTTGTTGTTTGAAATTGGTCTAGAGTCTAATATTAGAGATTTAATGCAAGTTGGTGTTCAGTCGCTA
ATTGTTGCAACTGTTGGTGTAGTATTGCCTTTCGTCGGAGGTACGGCAGGAATGATGGCGATCTTCCATGTATCAGCAGT
ACCAGCAGTTTTTGCTGGGGCAGCACTTACAGCTACCAGTATCGGTATCACTTCCAGGGTACTAACAGAAATTAACCGTC
TCAATACACAAGAAGGTCAAATTATTCTTGGTGCTGCAGTTATAGATGATGTGATGGGTATTATTATCTTGGCAGTTGTA
GCAAGTTTAGCAAAAACTGGTGAAGTGGATATCATCAATGTTGTTTATCTAATTATTAGTGCTAGTGTATTTTTGGTAGG
TGCGATCTTACTTGGTCGTTTCTTTAATGATGGTTTTGTGTTCTTTGCTGAAAAATTTAAAACCCGAGGAAGGGCAGTTA
TTCCAGCTTTGACTATCGCATTATTTATGGCTTACATTGGTACTGCTATCCATTTGGAGGCAATATTGGGAGCTTTTGCT
GCTGGATTAGTTTTAGATAATTTAGATCAAAAAGAAGTTGGACGGGAGTTGGAAGAGCTAATTCGTCCTATTTCTGATGT
GATCGTTCCTATTTTCTTTGTTACTGTGGGAACAAAAACTAATCTAAATGTTCTCAACCCAGCTATTCCTACTAACCGTG
AAGGTTTGGTGATTGCAATTTTTTTGATAGCAGTTGCTATTGTTGGTAAGGTTGCCTGCGGTTTTAGTGTGTTTGGTTTG
GGTCCAATTAATCGTTTAGCTATTGGTGTTGGTATGGTCCCACGGGGTGAGGTTGGTTTGGTTTTTGCCTCTGTTGGTTC
TGCTAGTGGTGCTTTATCTCCTGCTTTGGATGTGGCAATTATTCTGATGGTGATTCTTACAACATTTCTAGCGCCTCCCC
TACTGCGAGTAGTGTTTGGAAAAGCAGAAGCGGAAACAGAAGAAGTTCCGGAAACTTCCGGTTAG

Upstream 100 bases:

>100_bases
ATGCTCCTCTATACTTATCTGAAGTGATCATTTCCAAATTAACAAACCACTACTGCCCAAAGTCTTGTTAAATTAAATCA
GGATGATTTAGAAAGACTTA

Downstream 100 bases:

>100_bases
TTTTGAGGTGTTGCTGAATGTGGGTACGTTACATTAGTAGCATGGACGTCTTACGAGTTACTAATATTTTCTTAAGTCAG
GAATTTCATACTTGCAATTG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MFSLMAESNFFSEIFLFPLSGKIAPILATATETGAEPEMVLAGVLLSLVAIYIASKAGGEFFSWLNFPPVLGELVGGVVI
GISALHLVIFPESGADSSSSVIINILEATAGLAPEAAGATLQAQSEVLDVLAELGVIILLFEIGLESNIRDLMQVGVQSL
IVATVGVVLPFVGGTAGMMAIFHVSAVPAVFAGAALTATSIGITSRVLTEINRLNTQEGQIILGAAVIDDVMGIIILAVV
ASLAKTGEVDIINVVYLIISASVFLVGAILLGRFFNDGFVFFAEKFKTRGRAVIPALTIALFMAYIGTAIHLEAILGAFA
AGLVLDNLDQKEVGRELEELIRPISDVIVPIFFVTVGTKTNLNVLNPAIPTNREGLVIAIFLIAVAIVGKVACGFSVFGL
GPINRLAIGVGMVPRGEVGLVFASVGSASGALSPALDVAIILMVILTTFLAPPLLRVVFGKAEAETEEVPETSG

Sequences:

>Translated_474_residues
MFSLMAESNFFSEIFLFPLSGKIAPILATATETGAEPEMVLAGVLLSLVAIYIASKAGGEFFSWLNFPPVLGELVGGVVI
GISALHLVIFPESGADSSSSVIINILEATAGLAPEAAGATLQAQSEVLDVLAELGVIILLFEIGLESNIRDLMQVGVQSL
IVATVGVVLPFVGGTAGMMAIFHVSAVPAVFAGAALTATSIGITSRVLTEINRLNTQEGQIILGAAVIDDVMGIIILAVV
ASLAKTGEVDIINVVYLIISASVFLVGAILLGRFFNDGFVFFAEKFKTRGRAVIPALTIALFMAYIGTAIHLEAILGAFA
AGLVLDNLDQKEVGRELEELIRPISDVIVPIFFVTVGTKTNLNVLNPAIPTNREGLVIAIFLIAVAIVGKVACGFSVFGL
GPINRLAIGVGMVPRGEVGLVFASVGSASGALSPALDVAIILMVILTTFLAPPLLRVVFGKAEAETEEVPETSG
>Mature_474_residues
MFSLMAESNFFSEIFLFPLSGKIAPILATATETGAEPEMVLAGVLLSLVAIYIASKAGGEFFSWLNFPPVLGELVGGVVI
GISALHLVIFPESGADSSSSVIINILEATAGLAPEAAGATLQAQSEVLDVLAELGVIILLFEIGLESNIRDLMQVGVQSL
IVATVGVVLPFVGGTAGMMAIFHVSAVPAVFAGAALTATSIGITSRVLTEINRLNTQEGQIILGAAVIDDVMGIIILAVV
ASLAKTGEVDIINVVYLIISASVFLVGAILLGRFFNDGFVFFAEKFKTRGRAVIPALTIALFMAYIGTAIHLEAILGAFA
AGLVLDNLDQKEVGRELEELIRPISDVIVPIFFVTVGTKTNLNVLNPAIPTNREGLVIAIFLIAVAIVGKVACGFSVFGL
GPINRLAIGVGMVPRGEVGLVFASVGSASGALSPALDVAIILMVILTTFLAPPLLRVVFGKAEAETEEVPETSG

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=345, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322367, Length=424, Percent_Identity=26.8867924528302, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 49140; Mature: 49140

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSLMAESNFFSEIFLFPLSGKIAPILATATETGAEPEMVLAGVLLSLVAIYIASKAGGE
CCCCCCCCCCHHHHEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
FFSWLNFPPVLGELVGGVVIGISALHLVIFPESGADSSSSVIINILEATAGLAPEAAGAT
HHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
LQAQSEVLDVLAELGVIILLFEIGLESNIRDLMQVGVQSLIVATVGVVLPFVGGTAGMMA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IFHVSAVPAVFAGAALTATSIGITSRVLTEINRLNTQEGQIILGAAVIDDVMGIIILAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH
ASLAKTGEVDIINVVYLIISASVFLVGAILLGRFFNDGFVFFAEKFKTRGRAVIPALTIA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHH
LFMAYIGTAIHLEAILGAFAAGLVLDNLDQKEVGRELEELIRPISDVIVPIFFVTVGTKT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
NLNVLNPAIPTNREGLVIAIFLIAVAIVGKVACGFSVFGLGPINRLAIGVGMVPRGEVGL
CCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHCCCCCCCCCEE
VFASVGSASGALSPALDVAIILMVILTTFLAPPLLRVVFGKAEAETEEVPETSG
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCC
>Mature Secondary Structure
MFSLMAESNFFSEIFLFPLSGKIAPILATATETGAEPEMVLAGVLLSLVAIYIASKAGGE
CCCCCCCCCCHHHHEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
FFSWLNFPPVLGELVGGVVIGISALHLVIFPESGADSSSSVIINILEATAGLAPEAAGAT
HHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
LQAQSEVLDVLAELGVIILLFEIGLESNIRDLMQVGVQSLIVATVGVVLPFVGGTAGMMA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IFHVSAVPAVFAGAALTATSIGITSRVLTEINRLNTQEGQIILGAAVIDDVMGIIILAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH
ASLAKTGEVDIINVVYLIISASVFLVGAILLGRFFNDGFVFFAEKFKTRGRAVIPALTIA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHH
LFMAYIGTAIHLEAILGAFAAGLVLDNLDQKEVGRELEELIRPISDVIVPIFFVTVGTKT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
NLNVLNPAIPTNREGLVIAIFLIAVAIVGKVACGFSVFGLGPINRLAIGVGMVPRGEVGL
CCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHCCCCCCCCCEE
VFASVGSASGALSPALDVAIILMVILTTFLAPPLLRVVFGKAEAETEEVPETSG
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]