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The map label for this gene is gltA [H]

Identifier: 113475272

GI number: 113475272

Start: 2416673

End: 2417824

Strand: Reverse

Name: gltA [H]

Synonym: Tery_1580

Alternate gene names: 113475272

Gene position: 2417824-2416673 (Counterclockwise)

Preceding gene: 113475273

Following gene: 113475271

Centisome position: 31.2

GC content: 40.1

Gene sequence:

>1152_bases
ATGTCCGTCGTCTGCATTGAATTTAAGCCTGGTTTAGAAGGTGTTCCTGCTACCCAATCAAGTGTCAGCTACGTCGATGG
ACAAAAAGGGATATTGGAATACCGAGGCATTAATATTGAAGAATTGGCAAAAAAGAGTTCTTTTCTGGAAGCAGCATATT
TGTTAATTTGGGGCAACCTTCCTACTCAAGAAGAATTGCAAAGCTTTGAGCAAGAGATTTGCCTAAACAGAAGAATCAAA
TATAGAATTCGGGACATGATGAAATGTTTCCCGGAGACTGGACATCCTATGGATGCTCTACAGACTTCAGCAGCAGCTCT
GGGTTTATTTTATTCTCGTCGTGCTCTTGATAACCCAGAATATATTAGGAAAGCAGTAGTCAGGCTACTGGCCAATATAC
CCACAATGGTAGCTGCCTTTGAGTTAATGCGTAAAGGTAACGATCCTGTAAAGCCAAGGGATGACTTGGGCTATGCAGCC
AACTTTTTGTATATGCTCAATGAAAGAGAACCCGATCCATTAGCAGCAAAAGTATTTGATATTTGTCTGACTCTTCATGC
TGAACATACTATTAATGCTTCTACATTCTCAGCAATGGTAACTGCTTCTACCTTAACTGATCCCTACGGAGTTATAGCTT
CAGCAGTGGGAACTCTTGCCGGTCCACTACATGGGGGGGCAAATGAAGATGTAATTAGTATGTTGTCTGAAATTGGTTCG
GTAGAAAATGTTAAACCATATTTAAAACGATGTTTTGAGACTAAGGCCAAAATTGCGGGTTTTGGTCACCGAGTCTATAA
AGTAAAAGATCCAAGAGCTATCATCCTTCAGGAACTAGCAGTAGATTTATTTGAAAAGTTTGGCGACGACAAGTATTATC
AGATAGCTCTAGAAATGGAAAAGGTGGTAGAGGAAAAACTAGGTCACAAAGGAATTTACCCAAATGTGGATTTTTATTCT
GGTCTTGTTTATCGGAAATTAGGTATTCCTAGCGATTTATTTACCCCTGTATTTGCCATTGCTCGTGTGGCTGGTTGGTT
AGCTCACTGGAAAGAGCAATTAGCAGCCAATCGAATTTTCCGTCCTACACAAATTTATTCCGGAGATCATAATATTGCTT
ATACTTCCCTTGAAGAGCGAGCCTTAATCTAA

Upstream 100 bases:

>100_bases
TAACTAAAACTATTAATATTTTATTGTTAAAAAAATAACACAACTCAACTACTTGATAATGTAGCTTGAGTATATTCATA
TCTAAATAAAGGGGATCATC

Downstream 100 bases:

>100_bases
TTCTTTATGTTGTATTAAGTGCAAACAAGATTAAGCAATTCATGCCAGGAACCTGTGAGAATTGCCTAATTTCAAGGGTT
TAGGATAGGAAAATTAGCTG

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSVVCIEFKPGLEGVPATQSSVSYVDGQKGILEYRGINIEELAKKSSFLEAAYLLIWGNLPTQEELQSFEQEICLNRRIK
YRIRDMMKCFPETGHPMDALQTSAAALGLFYSRRALDNPEYIRKAVVRLLANIPTMVAAFELMRKGNDPVKPRDDLGYAA
NFLYMLNEREPDPLAAKVFDICLTLHAEHTINASTFSAMVTASTLTDPYGVIASAVGTLAGPLHGGANEDVISMLSEIGS
VENVKPYLKRCFETKAKIAGFGHRVYKVKDPRAIILQELAVDLFEKFGDDKYYQIALEMEKVVEEKLGHKGIYPNVDFYS
GLVYRKLGIPSDLFTPVFAIARVAGWLAHWKEQLAANRIFRPTQIYSGDHNIAYTSLEERALI

Sequences:

>Translated_383_residues
MSVVCIEFKPGLEGVPATQSSVSYVDGQKGILEYRGINIEELAKKSSFLEAAYLLIWGNLPTQEELQSFEQEICLNRRIK
YRIRDMMKCFPETGHPMDALQTSAAALGLFYSRRALDNPEYIRKAVVRLLANIPTMVAAFELMRKGNDPVKPRDDLGYAA
NFLYMLNEREPDPLAAKVFDICLTLHAEHTINASTFSAMVTASTLTDPYGVIASAVGTLAGPLHGGANEDVISMLSEIGS
VENVKPYLKRCFETKAKIAGFGHRVYKVKDPRAIILQELAVDLFEKFGDDKYYQIALEMEKVVEEKLGHKGIYPNVDFYS
GLVYRKLGIPSDLFTPVFAIARVAGWLAHWKEQLAANRIFRPTQIYSGDHNIAYTSLEERALI
>Mature_382_residues
SVVCIEFKPGLEGVPATQSSVSYVDGQKGILEYRGINIEELAKKSSFLEAAYLLIWGNLPTQEELQSFEQEICLNRRIKY
RIRDMMKCFPETGHPMDALQTSAAALGLFYSRRALDNPEYIRKAVVRLLANIPTMVAAFELMRKGNDPVKPRDDLGYAAN
FLYMLNEREPDPLAAKVFDICLTLHAEHTINASTFSAMVTASTLTDPYGVIASAVGTLAGPLHGGANEDVISMLSEIGSV
ENVKPYLKRCFETKAKIAGFGHRVYKVKDPRAIILQELAVDLFEKFGDDKYYQIALEMEKVVEEKLGHKGIYPNVDFYSG
LVYRKLGIPSDLFTPVFAIARVAGWLAHWKEQLAANRIFRPTQIYSGDHNIAYTSLEERALI

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=379, Percent_Identity=27.1767810026385, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1786939, Length=373, Percent_Identity=37.2654155495979, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1786527, Length=370, Percent_Identity=34.5945945945946, Blast_Score=230, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17555174, Length=373, Percent_Identity=27.3458445040214, Blast_Score=118, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319850, Length=378, Percent_Identity=26.7195767195767, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325257, Length=398, Percent_Identity=25.1256281407035, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324328, Length=368, Percent_Identity=24.7282608695652, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24640126, Length=377, Percent_Identity=27.3209549071618, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24640124, Length=377, Percent_Identity=27.3209549071618, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21356863, Length=392, Percent_Identity=26.530612244898, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 42873; Mature: 42742

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVCIEFKPGLEGVPATQSSVSYVDGQKGILEYRGINIEELAKKSSFLEAAYLLIWGNL
CCEEEEEECCCCCCCCCCCCCCHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHEEECCC
PTQEELQSFEQEICLNRRIKYRIRDMMKCFPETGHPMDALQTSAAALGLFYSRRALDNPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
YIRKAVVRLLANIPTMVAAFELMRKGNDPVKPRDDLGYAANFLYMLNEREPDPLAAKVFD
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
ICLTLHAEHTINASTFSAMVTASTLTDPYGVIASAVGTLAGPLHGGANEDVISMLSEIGS
HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
VENVKPYLKRCFETKAKIAGFGHRVYKVKDPRAIILQELAVDLFEKFGDDKYYQIALEME
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
KVVEEKLGHKGIYPNVDFYSGLVYRKLGIPSDLFTPVFAIARVAGWLAHWKEQLAANRIF
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPTQIYSGDHNIAYTSLEERALI
CCCEEECCCCCEEEECHHHHCCC
>Mature Secondary Structure 
SVVCIEFKPGLEGVPATQSSVSYVDGQKGILEYRGINIEELAKKSSFLEAAYLLIWGNL
CEEEEEECCCCCCCCCCCCCCHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHEEECCC
PTQEELQSFEQEICLNRRIKYRIRDMMKCFPETGHPMDALQTSAAALGLFYSRRALDNPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
YIRKAVVRLLANIPTMVAAFELMRKGNDPVKPRDDLGYAANFLYMLNEREPDPLAAKVFD
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
ICLTLHAEHTINASTFSAMVTASTLTDPYGVIASAVGTLAGPLHGGANEDVISMLSEIGS
HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
VENVKPYLKRCFETKAKIAGFGHRVYKVKDPRAIILQELAVDLFEKFGDDKYYQIALEME
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
KVVEEKLGHKGIYPNVDFYSGLVYRKLGIPSDLFTPVFAIARVAGWLAHWKEQLAANRIF
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPTQIYSGDHNIAYTSLEERALI
CCCEEECCCCCEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]