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The map label for this gene is argF [H]

Identifier: 113475056

GI number: 113475056

Start: 2017345

End: 2018265

Strand: Direct

Name: argF [H]

Synonym: Tery_1323

Alternate gene names: 113475056

Gene position: 2017345-2018265 (Clockwise)

Preceding gene: 113475054

Following gene: 113475057

Centisome position: 26.03

GC content: 33.77

Gene sequence:

>921_bases
ATGGATAAATTAAAAGGACGAGATTTATTAAGTCTGGCAAACTTGAATTCTGAAGAATTAAAAGAAATTTTACAATTAGC
AGCCCAACTAAAATCGGGTGAAATAAATCTTAAATGTAATAAAGTACTAGGATTATTATTTTCTAAAGCATCTACAAGAA
CCAGGGTAAGTTTTACCGTAGCAATGTATCAATTGGGAGGTCAAGTTATTGATTTGAATCCTAATGTTACTCAGGTTAGT
CGGGGAGAAAGTTTGGAAGATACTGCTAGGGTTTTAGACGGATATTTAGATATTTTAGCAATTCGTACTTTTGAACAAAA
AGACTTAGAAAGTTTTGCAAATTATGCAAAAATTCCTGTTATTAATGCTCTTACAGATAGGGAACATCCTTGTCAGATAT
TAGCTGATTTATTAACTGTTCAAGAAAATTTTGGCAAGCTAGATGGAATAACTTTAAGTTATTTTGGTGATGGTAATAAT
GTGGCAAATTCTTTACTATTAGGTTGTGCAATGGTAGGAATAAATGTCAGGATAGCAACTCCAGAAAATTATCTGCCAAA
TAAGGAAATTGTGGAACAAGCAAAGACTATTGCTAATGGTAAAAGTGAAGTTCTAGTTACTCAAGACCCCCAGGTAGCAG
TTAAGGATAGTCAAGTGCTTTATACTGATGTTTGGGCAAGCATGGGACAAGAACAGGAAGCGAATAATCGAATTCCTATT
TTTCAGCCTTATCAAGTTAATGAAAAGTTGGTAGAAAGTGCGGCAGATGATGTAATAATTTTACATTGTTTACCAGCACA
TAGGGATGAGGAAATTACTGATGCAGTAATAGAAGGAAAGAAATCACTAGTTTGGGAGCAAGCAGAAAATCGAATGCACG
CTCAAAAAGCTTTATTGATAAGTATCTTAGGAAGTGATTAG

Upstream 100 bases:

>100_bases
GTTTTAAAGAAAAATGGTTAGTTGTAAAAATTTGGCTGCCATTTATTAAACCTGTTCTTATCTTTTTTAAAGGTTATTGA
CCTAACATTAGTAGTAAATT

Downstream 100 bases:

>100_bases
AGCTTACAAAAAAAGTTGAGTTGTATAGTACTACGCGCAAGTAAAAAGTCAACCTCTTCTTTCCCTCAGAGTTTATTTTT
TTAACTAGAAAAAAATTTCT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDKLKGRDLLSLANLNSEELKEILQLAAQLKSGEINLKCNKVLGLLFSKASTRTRVSFTVAMYQLGGQVIDLNPNVTQVS
RGESLEDTARVLDGYLDILAIRTFEQKDLESFANYAKIPVINALTDREHPCQILADLLTVQENFGKLDGITLSYFGDGNN
VANSLLLGCAMVGINVRIATPENYLPNKEIVEQAKTIANGKSEVLVTQDPQVAVKDSQVLYTDVWASMGQEQEANNRIPI
FQPYQVNEKLVESAADDVIILHCLPAHRDEEITDAVIEGKKSLVWEQAENRMHAQKALLISILGSD

Sequences:

>Translated_306_residues
MDKLKGRDLLSLANLNSEELKEILQLAAQLKSGEINLKCNKVLGLLFSKASTRTRVSFTVAMYQLGGQVIDLNPNVTQVS
RGESLEDTARVLDGYLDILAIRTFEQKDLESFANYAKIPVINALTDREHPCQILADLLTVQENFGKLDGITLSYFGDGNN
VANSLLLGCAMVGINVRIATPENYLPNKEIVEQAKTIANGKSEVLVTQDPQVAVKDSQVLYTDVWASMGQEQEANNRIPI
FQPYQVNEKLVESAADDVIILHCLPAHRDEEITDAVIEGKKSLVWEQAENRMHAQKALLISILGSD
>Mature_306_residues
MDKLKGRDLLSLANLNSEELKEILQLAAQLKSGEINLKCNKVLGLLFSKASTRTRVSFTVAMYQLGGQVIDLNPNVTQVS
RGESLEDTARVLDGYLDILAIRTFEQKDLESFANYAKIPVINALTDREHPCQILADLLTVQENFGKLDGITLSYFGDGNN
VANSLLLGCAMVGINVRIATPENYLPNKEIVEQAKTIANGKSEVLVTQDPQVAVKDSQVLYTDVWASMGQEQEANNRIPI
FQPYQVNEKLVESAADDVIILHCLPAHRDEEITDAVIEGKKSLVWEQAENRMHAQKALLISILGSD

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=309, Percent_Identity=43.6893203883495, Blast_Score=243, Evalue=1e-64,
Organism=Homo sapiens, GI18105007, Length=318, Percent_Identity=27.6729559748428, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1790703, Length=333, Percent_Identity=39.039039039039, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1786469, Length=333, Percent_Identity=37.5375375375375, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI2367364, Length=326, Percent_Identity=28.2208588957055, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48994908, Length=359, Percent_Identity=26.1838440111421, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193204318, Length=329, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322373, Length=310, Percent_Identity=34.8387096774194, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322331, Length=315, Percent_Identity=30.1587301587302, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24642586, Length=317, Percent_Identity=28.391167192429, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 33794; Mature: 33794

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLKGRDLLSLANLNSEELKEILQLAAQLKSGEINLKCNKVLGLLFSKASTRTRVSFTV
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEEEEEE
AMYQLGGQVIDLNPNVTQVSRGESLEDTARVLDGYLDILAIRTFEQKDLESFANYAKIPV
EEHHHCCEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCE
INALTDREHPCQILADLLTVQENFGKLDGITLSYFGDGNNVANSLLLGCAMVGINVRIAT
EEHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEEEEC
PENYLPNKEIVEQAKTIANGKSEVLVTQDPQVAVKDSQVLYTDVWASMGQEQEANNRIPI
CCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEECCCEEEHHHHHHHCCCCCCCCCCCCE
FQPYQVNEKLVESAADDVIILHCLPAHRDEEITDAVIEGKKSLVWEQAENRMHAQKALLI
ECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHE
SILGSD
EEECCC
>Mature Secondary Structure
MDKLKGRDLLSLANLNSEELKEILQLAAQLKSGEINLKCNKVLGLLFSKASTRTRVSFTV
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEEEEEE
AMYQLGGQVIDLNPNVTQVSRGESLEDTARVLDGYLDILAIRTFEQKDLESFANYAKIPV
EEHHHCCEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCE
INALTDREHPCQILADLLTVQENFGKLDGITLSYFGDGNNVANSLLLGCAMVGINVRIAT
EEHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEEEEC
PENYLPNKEIVEQAKTIANGKSEVLVTQDPQVAVKDSQVLYTDVWASMGQEQEANNRIPI
CCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEECCCEEEHHHHHHHCCCCCCCCCCCCE
FQPYQVNEKLVESAADDVIILHCLPAHRDEEITDAVIEGKKSLVWEQAENRMHAQKALLI
ECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHE
SILGSD
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA