Click here to switch to the map view.

The map label for this gene is efp

Identifier: 113475050

GI number: 113475050

Start: 2005048

End: 2005605

Strand: Direct

Name: efp

Synonym: Tery_1313

Alternate gene names: 113475050

Gene position: 2005048-2005605 (Clockwise)

Preceding gene: 113475047

Following gene: 113475051

Centisome position: 25.87

GC content: 38.89

Gene sequence:

>558_bases
ATGATTTCTAGTAATGATTTTCGCCCCGGTGTGACCATAGAATTAGATGGTTCAGTTTGGCGAGTAGTAGAATTTTTACA
CGTTAAACCAGGCAAAGGTTCTGCTTTTGTTAGAACAAAGCTCAAAAATGTACAAAATGGTAATGTTGTGGAACGAACTT
TTAGAGCTGGAGAAACAGTCCCTCAAGCTACTTTGGACAAGAGAGCGATGCAGCATACATATAAAGATAGTGACCAATTT
GTATTTATGGATATGGAAACCTATGAAGAGACCAATTTAAGTTCTGAACAAATTGGTGAGCGTGTTAAGTATCTGAATGA
AGGGATGGAGGTCAATGTTATTATGTGGGGTGAACAAGTAATAGAGGTGGAGCTACCCAATTCTGTAGTATTAGAAGTAA
TCGAAACTGACCCTGGGGTTAAAGGAGATACTGCTACTGGTGGTAGTAAACCTGCTACAGTAGAAACAGGTGCCCAAATT
ATGGTTCCCTTGTTTATATCCAAAGGAGAACGGATTAAAATAGATACCCGTAATGACTCTTACTTGGGTAGAGAGTAA

Upstream 100 bases:

>100_bases
CCTAAGTGATAAACTCCTGAAAATATTTATAGAGAGTATTGTAGGATGTCTAATGTTAACTTCTAATTGAAACAATTAAA
AACCGCAATCACGGTGTTAT

Downstream 100 bases:

>100_bases
TTCTAGGGTACTTATTTTGGCAGGGTTATTATTCCCCTGCCTTTTGGTGTTAAATTCTATATTTATAGCAGCATTCTACT
TTAAGAAGTAAATATACTGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MISSNDFRPGVTIELDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVERTFRAGETVPQATLDKRAMQHTYKDSDQF
VFMDMETYEETNLSSEQIGERVKYLNEGMEVNVIMWGEQVIEVELPNSVVLEVIETDPGVKGDTATGGSKPATVETGAQI
MVPLFISKGERIKIDTRNDSYLGRE

Sequences:

>Translated_185_residues
MISSNDFRPGVTIELDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVERTFRAGETVPQATLDKRAMQHTYKDSDQF
VFMDMETYEETNLSSEQIGERVKYLNEGMEVNVIMWGEQVIEVELPNSVVLEVIETDPGVKGDTATGGSKPATVETGAQI
MVPLFISKGERIKIDTRNDSYLGRE
>Mature_185_residues
MISSNDFRPGVTIELDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVERTFRAGETVPQATLDKRAMQHTYKDSDQF
VFMDMETYEETNLSSEQIGERVKYLNEGMEVNVIMWGEQVIEVELPNSVVLEVIETDPGVKGDTATGGSKPATVETGAQI
MVPLFISKGERIKIDTRNDSYLGRE

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=44.1988950276243, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=33.5106382978723, Blast_Score=118, Evalue=3e-28,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_TRIEI (Q116D6)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721111.1
- ProteinModelPortal:   Q116D6
- SMR:   Q116D6
- STRING:   Q116D6
- GeneID:   4242464
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_1313
- NMPDR:   fig|203124.1.peg.4852
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q116D6
- ProtClustDB:   PRK00529
- BioCyc:   TERY203124:TERY_1313-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20674; Mature: 20674

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSNDFRPGVTIELDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVERTFRAGETV
CCCCCCCCCCEEEEECCCHHHEEHHHCCCCCCCCCEEEEEHHCCCCCCHHHHHHHCCCCC
PQATLDKRAMQHTYKDSDQFVFMDMETYEETNLSSEQIGERVKYLNEGMEVNVIMWGEQV
CHHHHHHHHHHHHCCCCCCEEEEEECHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCEE
IEVELPNSVVLEVIETDPGVKGDTATGGSKPATVETGAQIMVPLFISKGERIKIDTRNDS
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCCC
YLGRE
CCCCC
>Mature Secondary Structure
MISSNDFRPGVTIELDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVERTFRAGETV
CCCCCCCCCCEEEEECCCHHHEEHHHCCCCCCCCCEEEEEHHCCCCCCHHHHHHHCCCCC
PQATLDKRAMQHTYKDSDQFVFMDMETYEETNLSSEQIGERVKYLNEGMEVNVIMWGEQV
CHHHHHHHHHHHHCCCCCCEEEEEECHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCEE
IEVELPNSVVLEVIETDPGVKGDTATGGSKPATVETGAQIMVPLFISKGERIKIDTRNDS
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCCC
YLGRE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA