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The map label for this gene is engD [H]

Identifier: 113475013

GI number: 113475013

Start: 1944894

End: 1945985

Strand: Reverse

Name: engD [H]

Synonym: Tery_1259

Alternate gene names: 113475013

Gene position: 1945985-1944894 (Counterclockwise)

Preceding gene: 113475014

Following gene: 113475012

Centisome position: 25.11

GC content: 35.62

Gene sequence:

>1092_bases
ATGCTCAGAGCTGGAATTGTCGGACTACCCAACGTAGGAAAATCTACCTTATTTAATGCTTTAGTTGCTAATGCTAAGGC
GGAAGCTGCTAACTTCCCATTTTGCACAATTGAACCCAATGTTGGTGTAGTAGCTGTGCCAGATAATCGGTTAAATGTGC
TGGCTCAAATTTCTAATTCTGCCCAAACTGTTCCTACTAGAATTGAGTTTGTTGATATTGCTGGTTTAGTAAAAGGTGCA
AGCAAAGGAGAAGGTTTAGGTAATCAATTTTTATCTAATATTCGAGAGGTTGATGCTATTGTTCAAGTAGTTCGTTGTTT
TGATAGTGAAGATATTATTCATGTCTCTGGTTCTGTGGATCCAGTGCGAGATATTGAGGTAATTAATTTAGAATTAGCTT
TATCCGATCTAGCTCAGGTAGAACGACGAATTGAACGGACTAAAAAACAAGCTCGTACCAGTAAAGAAGCTCAGACAGAA
TTAGAAGTTTTAGAAAAATTAGAGGTTGTTTTAAATGAAGGTAATTCGGTAAAAATGGCTGGTTTAAATAAAGATGAATC
TTTGATAATTAAGCCTTTAAATTTATTAACTTCTAAGCCCATAATTTATGCAGCTAATGTCTCAGAAGATGATTTGGCTA
ATGGGAATGACTGGGTTGAAAAAGTTCGCAATATTGCTGCTGTAGAAAATGCTCAAGTTGTGGTAATTTCAGCTCAAGTA
GAATCAGAATTAATTGAGTTACCTGAGGAAGAAATAACTGATTATTTGAAATCTTTAGGAGTAGAAGAAGGTGGTTTAAA
ATCTTTGATTAAAGCGACTTATGAATTGTTGGGATTGCATACTTATTTTACTACTGGAGAGAAAGAAACTAAAGCTTGGA
CAATTAAGGCTGGAACTTTAGCTCCTCAAGCTGCTGGTGTAATTCATACTGATTTTGAACGAGGTTTTATTCGAGCAGAA
ACAATTGCTTATAAGGATCTAGTAACCAGTGGTTCAATGACTACTGCTAAGGAGAAAGGTTTAGTAAGGAGTGAAGGCAA
GGATTATCTTGTTAAGGAAGGTGATATTATGCTCTTCCGATTTAATGTTTAG

Upstream 100 bases:

>100_bases
CTTCTTTCCTTCTGTTATCCTGAGTAGATAGGCAGTTTTATAGTAACCCTATCTGTAATTTCTTTAATTTTTAACTTTTA
AATATTGTTGACTTAAATTT

Downstream 100 bases:

>100_bases
ATTGCTGTTAATTAAGGAGAAAAAAAATGAGTATTTTACAACTTTTGATTCTTTGGTTTGTGACTGCTGTTAGTTTATTT
ATTATTTCTAAGTTACCAAC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLRAGIVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVAVPDNRLNVLAQISNSAQTVPTRIEFVDIAGLVKGA
SKGEGLGNQFLSNIREVDAIVQVVRCFDSEDIIHVSGSVDPVRDIEVINLELALSDLAQVERRIERTKKQARTSKEAQTE
LEVLEKLEVVLNEGNSVKMAGLNKDESLIIKPLNLLTSKPIIYAANVSEDDLANGNDWVEKVRNIAAVENAQVVVISAQV
ESELIELPEEEITDYLKSLGVEEGGLKSLIKATYELLGLHTYFTTGEKETKAWTIKAGTLAPQAAGVIHTDFERGFIRAE
TIAYKDLVTSGSMTTAKEKGLVRSEGKDYLVKEGDIMLFRFNV

Sequences:

>Translated_363_residues
MLRAGIVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVAVPDNRLNVLAQISNSAQTVPTRIEFVDIAGLVKGA
SKGEGLGNQFLSNIREVDAIVQVVRCFDSEDIIHVSGSVDPVRDIEVINLELALSDLAQVERRIERTKKQARTSKEAQTE
LEVLEKLEVVLNEGNSVKMAGLNKDESLIIKPLNLLTSKPIIYAANVSEDDLANGNDWVEKVRNIAAVENAQVVVISAQV
ESELIELPEEEITDYLKSLGVEEGGLKSLIKATYELLGLHTYFTTGEKETKAWTIKAGTLAPQAAGVIHTDFERGFIRAE
TIAYKDLVTSGSMTTAKEKGLVRSEGKDYLVKEGDIMLFRFNV
>Mature_363_residues
MLRAGIVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVAVPDNRLNVLAQISNSAQTVPTRIEFVDIAGLVKGA
SKGEGLGNQFLSNIREVDAIVQVVRCFDSEDIIHVSGSVDPVRDIEVINLELALSDLAQVERRIERTKKQARTSKEAQTE
LEVLEKLEVVLNEGNSVKMAGLNKDESLIIKPLNLLTSKPIIYAANVSEDDLANGNDWVEKVRNIAAVENAQVVVISAQV
ESELIELPEEEITDYLKSLGVEEGGLKSLIKATYELLGLHTYFTTGEKETKAWTIKAGTLAPQAAGVIHTDFERGFIRAE
TIAYKDLVTSGSMTTAKEKGLVRSEGKDYLVKEGDIMLFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=43.75, Blast_Score=295, Evalue=5e-80,
Organism=Homo sapiens, GI58761502, Length=213, Percent_Identity=37.5586854460094, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI24308117, Length=153, Percent_Identity=30.0653594771242, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=57.3002754820937, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1789574, Length=140, Percent_Identity=33.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=43.1693989071038, Blast_Score=299, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=40.6417112299465, Blast_Score=259, Evalue=5e-70,
Organism=Saccharomyces cerevisiae, GI6321773, Length=382, Percent_Identity=40.8376963350785, Blast_Score=235, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6321649, Length=151, Percent_Identity=35.7615894039735, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=41.6666666666667, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=41.6666666666667, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=41.6666666666667, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640879, Length=330, Percent_Identity=38.4848484848485, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI24585318, Length=138, Percent_Identity=32.6086956521739, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39495; Mature: 39495

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRAGIVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVAVPDNRLNVLAQISNS
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCEEHEECCCC
AQTVPTRIEFVDIAGLVKGASKGEGLGNQFLSNIREVDAIVQVVRCFDSEDIIHVSGSVD
CCCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PVRDIEVINLELALSDLAQVERRIERTKKQARTSKEAQTELEVLEKLEVVLNEGNSVKMA
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GLNKDESLIIKPLNLLTSKPIIYAANVSEDDLANGNDWVEKVRNIAAVENAQVVVISAQV
CCCCCCCEEEEEHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECHH
ESELIELPEEEITDYLKSLGVEEGGLKSLIKATYELLGLHTYFTTGEKETKAWTIKAGTL
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCC
APQAAGVIHTDFERGFIRAETIAYKDLVTSGSMTTAKEKGLVRSEGKDYLVKEGDIMLFR
CCCCCCCEEECCCCCCEEHHHHHHHHHHCCCCCCCHHHCCCHHCCCCCEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure
MLRAGIVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVAVPDNRLNVLAQISNS
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCEEHEECCCC
AQTVPTRIEFVDIAGLVKGASKGEGLGNQFLSNIREVDAIVQVVRCFDSEDIIHVSGSVD
CCCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PVRDIEVINLELALSDLAQVERRIERTKKQARTSKEAQTELEVLEKLEVVLNEGNSVKMA
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GLNKDESLIIKPLNLLTSKPIIYAANVSEDDLANGNDWVEKVRNIAAVENAQVVVISAQV
CCCCCCCEEEEEHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECHH
ESELIELPEEEITDYLKSLGVEEGGLKSLIKATYELLGLHTYFTTGEKETKAWTIKAGTL
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCC
APQAAGVIHTDFERGFIRAETIAYKDLVTSGSMTTAKEKGLVRSEGKDYLVKEGDIMLFR
CCCCCCCEEECCCCCCEEHHHHHHHHHHCCCCCCCHHHCCCHHCCCCCEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]