Click here to switch to the map view.

The map label for this gene is pleD [H]

Identifier: 113474855

GI number: 113474855

Start: 1688760

End: 1690061

Strand: Direct

Name: pleD [H]

Synonym: Tery_1074

Alternate gene names: 113474855

Gene position: 1688760-1690061 (Clockwise)

Preceding gene: 113474851

Following gene: 113474856

Centisome position: 21.79

GC content: 28.96

Gene sequence:

>1302_bases
ATGACAAAAAAACTAAATTCAGAGCATATTTTAGTTGTAGATGATGTTCAAGCTAATCTTAAAGTAATAGTTAAAACTTT
AACTAATGAAGGATATAAAGTTTCTACAGCAATTAGCAGTGACCAAGCGCTCAAGCAAATTTCCTATGACTTACCTGATT
TAATTTTGCTAGATATACAAACCTCTGGTATTGATGGATTTGAAATTTGTCAAAGGTTAAAAGAAAATCCAGAAATGAAA
GACATCCCAGTAATTTTAATGGCTGTTCCTTCAAACATTAAAAATATAGTTAAAGGTTTGACATTGGGAGCCGTAGATTA
TATTACCATACCATTTCAAACAATTGAAGTCCTTAGTAAAGTAAAAAATCACATACATTTACAACAGTTAAAAAAGAATC
TCGAAAAAGAAGTAGCTAAGAAAACTTATGAACTTACTCAAGCTTTAGAGCAGTTAAAAGCATCTCAAGTCAAACCCATT
AAAAGTGAAGAAATGTTAGTAACGGGAGAATTAATGGCTGGAGTAGCAAATGAATTTAATCACCCCATTGGTTCAATTTA
TAGTAATTCTTTTTATTTAGAAACATACATAAAAAATATTTTGGAACATCTATTTCTTTATCAAAAAAATTATCCTAATC
CTGTAGCAGAAATTATTCAAAGTGCTGAAGATATTGATCTAGATTTTATTATAGAAGATTTCCCTAATATAATTACTTCT
ATAAAGACGAGCTCAGAAAGGATTAAATACCTGAGCTCATATTTACAAAAATTTCGTAAACAAAGTGTTATTACAGCCCA
TAAAAGTATTGATAGTGCTCTATTAATTTTGAAGCATCGCCTCAAAGCTAATCAGTATCGCTCCGGTATTAAAGTAGTCA
AAAAATATGGAGATTTGCCTAAGATGAAATGTCTGCCTGGACAATTAATTCAGGTATTTATGAATATAATTTATAATGCT
ATTGATGAGATTGATGAGTTTGGTAAGAAAGTAGGTTTTTCTAATTGTAAATTTGAGCCTAAAATTGTAATTAATACTTT
AATGAGTCATGATAAAAAAGAAGTAATTGTCACTATTAAAAACAATGGCATAGGAATGTCAGAAGAAGTTAAGAGAACAG
TTTTTGATAAGCTTTCTAATACTAGAGCTTTAGCTAAAGGAACAAGTTTAAGTTTATCTATTGCTCATCAAATTGTGGTC
AATAATTATCATGGTAAGCTTTGCTGTGAGTCAATTATAAATAAGGGGTCAAAATTTATTTTGCAATTACCAATAACAGA
AATGAGTAAGAATATGAGATAA

Upstream 100 bases:

>100_bases
GCAAAGTAAACCAAGATAAAACTAATCTCTAAAATTATAAGTACATTTGAAGTAGAATATTTTCTTATAAAATTTTCAGT
AAAAAATAAGGGGTAAATTA

Downstream 100 bases:

>100_bases
TAATATAATATAAGGTAGACAAAAAGGAAAGTAAATAATCAAGTATAAATGCTGGAAAATTAAAATTCACAGCTAATTCT
AATTTAGCTATCTATCAAAT

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Stalked cell differentiation-controlling protein; Diguanylate cyclase; DGC; Diguanylate kinase [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTKKLNSEHILVVDDVQANLKVIVKTLTNEGYKVSTAISSDQALKQISYDLPDLILLDIQTSGIDGFEICQRLKENPEMK
DIPVILMAVPSNIKNIVKGLTLGAVDYITIPFQTIEVLSKVKNHIHLQQLKKNLEKEVAKKTYELTQALEQLKASQVKPI
KSEEMLVTGELMAGVANEFNHPIGSIYSNSFYLETYIKNILEHLFLYQKNYPNPVAEIIQSAEDIDLDFIIEDFPNIITS
IKTSSERIKYLSSYLQKFRKQSVITAHKSIDSALLILKHRLKANQYRSGIKVVKKYGDLPKMKCLPGQLIQVFMNIIYNA
IDEIDEFGKKVGFSNCKFEPKIVINTLMSHDKKEVIVTIKNNGIGMSEEVKRTVFDKLSNTRALAKGTSLSLSIAHQIVV
NNYHGKLCCESIINKGSKFILQLPITEMSKNMR

Sequences:

>Translated_433_residues
MTKKLNSEHILVVDDVQANLKVIVKTLTNEGYKVSTAISSDQALKQISYDLPDLILLDIQTSGIDGFEICQRLKENPEMK
DIPVILMAVPSNIKNIVKGLTLGAVDYITIPFQTIEVLSKVKNHIHLQQLKKNLEKEVAKKTYELTQALEQLKASQVKPI
KSEEMLVTGELMAGVANEFNHPIGSIYSNSFYLETYIKNILEHLFLYQKNYPNPVAEIIQSAEDIDLDFIIEDFPNIITS
IKTSSERIKYLSSYLQKFRKQSVITAHKSIDSALLILKHRLKANQYRSGIKVVKKYGDLPKMKCLPGQLIQVFMNIIYNA
IDEIDEFGKKVGFSNCKFEPKIVINTLMSHDKKEVIVTIKNNGIGMSEEVKRTVFDKLSNTRALAKGTSLSLSIAHQIVV
NNYHGKLCCESIINKGSKFILQLPITEMSKNMR
>Mature_432_residues
TKKLNSEHILVVDDVQANLKVIVKTLTNEGYKVSTAISSDQALKQISYDLPDLILLDIQTSGIDGFEICQRLKENPEMKD
IPVILMAVPSNIKNIVKGLTLGAVDYITIPFQTIEVLSKVKNHIHLQQLKKNLEKEVAKKTYELTQALEQLKASQVKPIK
SEEMLVTGELMAGVANEFNHPIGSIYSNSFYLETYIKNILEHLFLYQKNYPNPVAEIIQSAEDIDLDFIIEDFPNIITSI
KTSSERIKYLSSYLQKFRKQSVITAHKSIDSALLILKHRLKANQYRSGIKVVKKYGDLPKMKCLPGQLIQVFMNIIYNAI
DEIDEFGKKVGFSNCKFEPKIVINTLMSHDKKEVIVTIKNNGIGMSEEVKRTVFDKLSNTRALAKGTSLSLSIAHQIVVN
NYHGKLCCESIINKGSKFILQLPITEMSKNMR

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Phosphorylated PleD localizes to the differentiating pole [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 response regulatory domains [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=33.6206896551724, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788394, Length=137, Percent_Identity=29.9270072992701, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=30.5785123966942, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=34.7107438016529, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR000160
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00990 GGDEF; PF00072 Response_reg [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 48950; Mature: 48819

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKLNSEHILVVDDVQANLKVIVKTLTNEGYKVSTAISSDQALKQISYDLPDLILLDIQ
CCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEE
TSGIDGFEICQRLKENPEMKDIPVILMAVPSNIKNIVKGLTLGAVDYITIPFQTIEVLSK
CCCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCHHEEECCHHHHHHHHH
VKNHIHLQQLKKNLEKEVAKKTYELTQALEQLKASQVKPIKSEEMLVTGELMAGVANEFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHC
HPIGSIYSNSFYLETYIKNILEHLFLYQKNYPNPVAEIIQSAEDIDLDFIIEDFPNIITS
CCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
IKTSSERIKYLSSYLQKFRKQSVITAHKSIDSALLILKHRLKANQYRSGIKVVKKYGDLP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KMKCLPGQLIQVFMNIIYNAIDEIDEFGKKVGFSNCKFEPKIVINTLMSHDKKEVIVTIK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
NNGIGMSEEVKRTVFDKLSNTRALAKGTSLSLSIAHQIVVNNYHGKLCCESIINKGSKFI
CCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
LQLPITEMSKNMR
EECCHHHHCCCCC
>Mature Secondary Structure 
TKKLNSEHILVVDDVQANLKVIVKTLTNEGYKVSTAISSDQALKQISYDLPDLILLDIQ
CCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEE
TSGIDGFEICQRLKENPEMKDIPVILMAVPSNIKNIVKGLTLGAVDYITIPFQTIEVLSK
CCCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCHHEEECCHHHHHHHHH
VKNHIHLQQLKKNLEKEVAKKTYELTQALEQLKASQVKPIKSEEMLVTGELMAGVANEFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHC
HPIGSIYSNSFYLETYIKNILEHLFLYQKNYPNPVAEIIQSAEDIDLDFIIEDFPNIITS
CCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
IKTSSERIKYLSSYLQKFRKQSVITAHKSIDSALLILKHRLKANQYRSGIKVVKKYGDLP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KMKCLPGQLIQVFMNIIYNAIDEIDEFGKKVGFSNCKFEPKIVINTLMSHDKKEVIVTIK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
NNGIGMSEEVKRTVFDKLSNTRALAKGTSLSLSIAHQIVVNNYHGKLCCESIINKGSKFI
CCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
LQLPITEMSKNMR
EECCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA