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The map label for this gene is ubiB [C]

Identifier: 113474827

GI number: 113474827

Start: 1633212

End: 1634891

Strand: Direct

Name: ubiB [C]

Synonym: Tery_1043

Alternate gene names: 113474827

Gene position: 1633212-1634891 (Clockwise)

Preceding gene: 113474826

Following gene: 113474828

Centisome position: 21.07

GC content: 31.85

Gene sequence:

>1680_bases
ATGCTCACTAAAAATTCTTCTAAGTCCCGACCTTGGCAACGCGCTCAATATTCTCCCTTAACCAGACAAATAGATGTTTT
TAGTGCGGCGGGAAAATTTTTTTTCTTTTTATGGTGGGATAATTTATTTCAAAATAAATCTTCAACTCTCAGGAGGCGTC
GGGCTGAATGGTTAGTCAAAACTATGATAAATTTAGGTCCAACTTTTATTAAAATAGGCCAATCTTTATCTACACGAGCT
GATATATTGCCGAAGGAATATGTGGAAGAATTAGGAAAATTACAAGACCAGGTGCCTCCTTTTGAAACTACGGAGGCGAT
CGCTATTATTGAGTCGGAACTTGGCAACTCTCTTTATTCTTTGTATCGAGATTTTAAGGAATTTCCTATCGCTGCAGCAA
GTCTTGGACAAGTACATAAAGCTAATTTACAAACTGGTGAGGAAGTTGTGGTTAAAATACAACGTCCTGGGTTAAAAGTT
TTATTTGACTTGGATGTGAAAGCTCTCAAAAATGTTATCCGTTTTTGTAAAAGGTATTTTGCTTGGGCTAAGAAGTATGA
TTTAGATGTTATTTACTATGATTTTTTTACAATTTTATATCAAGAAATTGATTATGTTAATGAGGGAAAAAATGCTGACC
GCTTTCGCGACAATTTTCAAGGATATCCTGATATAGTAGTGCCTCGTGTTTATTGGACTCACACTACAGAAAAAGTTATA
ACTCTTGAGTATTTACCGGGAATTAAAATTAATGATCGTAGGGAAATGGAAGCTTATAATCTTAATCCGAAGCTAATTAA
TCAAATAGGAGTTTGTTGTTATTTAAAGCAGTTATTGTTAGATGGTTTTTTTCAAGCTGACCCTCATCCAGGAAATTTAG
CAGTTAGTTCAGATGGCAAAGTTATTTTTTATGATTTTGGGATGATGGCTGAGGTCAAATCTTTAACTAAAGATCAAATG
ATTAAAACTTTTTTTGCTGTATTAAAAAAAGATGTTGAACAGGTTTTAAATGCTTTAATTACTATTGGTTTAATTGTACC
AATGTCTAATATGATGCCTGTGAGAAGATTACTTGATTTTTTATTGGAAAATTTTACTGATAAACCTGTCAATTTTTATG
ATTTTGATCAAATTAAGGAAGAACTTTATGTATTGTTTGAAGAACAACCATTTCGTCTCCCCTCTCAAATGACTTTTATT
CTTAAGTCACTTACTACTTTGGATGGTATTGCTAGAGAACTTGATCCTGATTATAGTTTAGTTAGTTGTTCTCAACCTTT
TGTTAAAAGTATAACTTTTTCTAAAGGTAAAGGTAGAGTTGTTGGTGAGTTAGCTAAACAGACTACAGATTTTATTAAGT
ATAAATTACGGCAACCTAGTAAAAGTGAAGTTTTAATCCGTCAATTCCAAACAAAAATTGAAGATGGTGAAATTCAGTTT
CGGGTACGTTCTATTGAACATGATCGGTTATTGAAACGGATTAATTTAGCTTTGAAAGTTTTGATTTTTACTGGTTTTAC
TGGTTTTACTTTTTTATCGGGATCTGTTTTACTGACTGGAGGTTATATTAAAGCTGCAATTATTATTTTTGTTTTATCGG
TATTGGGATTTATATTCCTATTAAAGTTAGGGTTTCAGTTATCTATTAAAGAAAAATTAGATAAAATAGCAGAAAAATAA

Upstream 100 bases:

>100_bases
GAGAATAATATTAGTAGTTATGTCAAGTATGTCAAGTTACAATTAACTAAAACTACAACATATATGTCGTTTCTTACAAT
AGATTTATATAGTTCTTTGT

Downstream 100 bases:

>100_bases
ATTACTACTAAATTACTACAGTGATCGCCTCATTTTTTCTATTACTTTTTTTGGTTGAATAAAAAGTATTATGTAGGGGC
AAACTTACCATGATCTATAA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MLTKNSSKSRPWQRAQYSPLTRQIDVFSAAGKFFFFLWWDNLFQNKSSTLRRRRAEWLVKTMINLGPTFIKIGQSLSTRA
DILPKEYVEELGKLQDQVPPFETTEAIAIIESELGNSLYSLYRDFKEFPIAAASLGQVHKANLQTGEEVVVKIQRPGLKV
LFDLDVKALKNVIRFCKRYFAWAKKYDLDVIYYDFFTILYQEIDYVNEGKNADRFRDNFQGYPDIVVPRVYWTHTTEKVI
TLEYLPGIKINDRREMEAYNLNPKLINQIGVCCYLKQLLLDGFFQADPHPGNLAVSSDGKVIFYDFGMMAEVKSLTKDQM
IKTFFAVLKKDVEQVLNALITIGLIVPMSNMMPVRRLLDFLLENFTDKPVNFYDFDQIKEELYVLFEEQPFRLPSQMTFI
LKSLTTLDGIARELDPDYSLVSCSQPFVKSITFSKGKGRVVGELAKQTTDFIKYKLRQPSKSEVLIRQFQTKIEDGEIQF
RVRSIEHDRLLKRINLALKVLIFTGFTGFTFLSGSVLLTGGYIKAAIIIFVLSVLGFIFLLKLGFQLSIKEKLDKIAEK

Sequences:

>Translated_559_residues
MLTKNSSKSRPWQRAQYSPLTRQIDVFSAAGKFFFFLWWDNLFQNKSSTLRRRRAEWLVKTMINLGPTFIKIGQSLSTRA
DILPKEYVEELGKLQDQVPPFETTEAIAIIESELGNSLYSLYRDFKEFPIAAASLGQVHKANLQTGEEVVVKIQRPGLKV
LFDLDVKALKNVIRFCKRYFAWAKKYDLDVIYYDFFTILYQEIDYVNEGKNADRFRDNFQGYPDIVVPRVYWTHTTEKVI
TLEYLPGIKINDRREMEAYNLNPKLINQIGVCCYLKQLLLDGFFQADPHPGNLAVSSDGKVIFYDFGMMAEVKSLTKDQM
IKTFFAVLKKDVEQVLNALITIGLIVPMSNMMPVRRLLDFLLENFTDKPVNFYDFDQIKEELYVLFEEQPFRLPSQMTFI
LKSLTTLDGIARELDPDYSLVSCSQPFVKSITFSKGKGRVVGELAKQTTDFIKYKLRQPSKSEVLIRQFQTKIEDGEIQF
RVRSIEHDRLLKRINLALKVLIFTGFTGFTFLSGSVLLTGGYIKAAIIIFVLSVLGFIFLLKLGFQLSIKEKLDKIAEK
>Mature_559_residues
MLTKNSSKSRPWQRAQYSPLTRQIDVFSAAGKFFFFLWWDNLFQNKSSTLRRRRAEWLVKTMINLGPTFIKIGQSLSTRA
DILPKEYVEELGKLQDQVPPFETTEAIAIIESELGNSLYSLYRDFKEFPIAAASLGQVHKANLQTGEEVVVKIQRPGLKV
LFDLDVKALKNVIRFCKRYFAWAKKYDLDVIYYDFFTILYQEIDYVNEGKNADRFRDNFQGYPDIVVPRVYWTHTTEKVI
TLEYLPGIKINDRREMEAYNLNPKLINQIGVCCYLKQLLLDGFFQADPHPGNLAVSSDGKVIFYDFGMMAEVKSLTKDQM
IKTFFAVLKKDVEQVLNALITIGLIVPMSNMMPVRRLLDFLLENFTDKPVNFYDFDQIKEELYVLFEEQPFRLPSQMTFI
LKSLTTLDGIARELDPDYSLVSCSQPFVKSITFSKGKGRVVGELAKQTTDFIKYKLRQPSKSEVLIRQFQTKIEDGEIQF
RVRSIEHDRLLKRINLALKVLIFTGFTGFTFLSGSVLLTGGYIKAAIIIFVLSVLGFIFLLKLGFQLSIKEKLDKIAEK

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=442, Percent_Identity=26.0180995475113, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI41393593, Length=376, Percent_Identity=28.1914893617021, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI217035081, Length=420, Percent_Identity=23.8095238095238, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI34147522, Length=303, Percent_Identity=29.042904290429, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI27363457, Length=305, Percent_Identity=28.8524590163934, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI217416386, Length=239, Percent_Identity=30.1255230125523, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI2367309, Length=400, Percent_Identity=28.75, Blast_Score=182, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17559152, Length=375, Percent_Identity=26.6666666666667, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32565180, Length=278, Percent_Identity=25.5395683453237, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323282, Length=286, Percent_Identity=25.5244755244755, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=240, Percent_Identity=30.8333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325148, Length=258, Percent_Identity=25.5813953488372, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24662575, Length=390, Percent_Identity=28.4615384615385, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI22024280, Length=321, Percent_Identity=27.4143302180685, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI18859849, Length=274, Percent_Identity=27.007299270073, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 64561; Mature: 64561

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01037 SBP_BACTERIAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKNSSKSRPWQRAQYSPLTRQIDVFSAAGKFFFFLWWDNLFQNKSSTLRRRRAEWLVK
CCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHH
TMINLGPTFIKIGQSLSTRADILPKEYVEELGKLQDQVPPFETTEAIAIIESELGNSLYS
HHHHCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LYRDFKEFPIAAASLGQVHKANLQTGEEVVVKIQRPGLKVLFDLDVKALKNVIRFCKRYF
HHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHH
AWAKKYDLDVIYYDFFTILYQEIDYVNEGKNADRFRDNFQGYPDIVVPRVYWTHTTEKVI
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEECCEEEECCCCEEE
TLEYLPGIKINDRREMEAYNLNPKLINQIGVCCYLKQLLLDGFFQADPHPGNLAVSSDGK
EEEECCCCEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
VIFYDFGMMAEVKSLTKDQMIKTFFAVLKKDVEQVLNALITIGLIVPMSNMMPVRRLLDF
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LLENFTDKPVNFYDFDQIKEELYVLFEEQPFRLPSQMTFILKSLTTLDGIARELDPDYSL
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VSCSQPFVKSITFSKGKGRVVGELAKQTTDFIKYKLRQPSKSEVLIRQFQTKIEDGEIQF
EECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEE
RVRSIEHDRLLKRINLALKVLIFTGFTGFTFLSGSVLLTGGYIKAAIIIFVLSVLGFIFL
EEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHH
LKLGFQLSIKEKLDKIAEK
HHHCCCEEHHHHHHHHHCC
>Mature Secondary Structure
MLTKNSSKSRPWQRAQYSPLTRQIDVFSAAGKFFFFLWWDNLFQNKSSTLRRRRAEWLVK
CCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHH
TMINLGPTFIKIGQSLSTRADILPKEYVEELGKLQDQVPPFETTEAIAIIESELGNSLYS
HHHHCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LYRDFKEFPIAAASLGQVHKANLQTGEEVVVKIQRPGLKVLFDLDVKALKNVIRFCKRYF
HHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHH
AWAKKYDLDVIYYDFFTILYQEIDYVNEGKNADRFRDNFQGYPDIVVPRVYWTHTTEKVI
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEECCEEEECCCCEEE
TLEYLPGIKINDRREMEAYNLNPKLINQIGVCCYLKQLLLDGFFQADPHPGNLAVSSDGK
EEEECCCCEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
VIFYDFGMMAEVKSLTKDQMIKTFFAVLKKDVEQVLNALITIGLIVPMSNMMPVRRLLDF
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LLENFTDKPVNFYDFDQIKEELYVLFEEQPFRLPSQMTFILKSLTTLDGIARELDPDYSL
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VSCSQPFVKSITFSKGKGRVVGELAKQTTDFIKYKLRQPSKSEVLIRQFQTKIEDGEIQF
EECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEE
RVRSIEHDRLLKRINLALKVLIFTGFTGFTFLSGSVLLTGGYIKAAIIIFVLSVLGFIFL
EEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHH
LKLGFQLSIKEKLDKIAEK
HHHCCCEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]