Click here to switch to the map view.

The map label for this gene is dapL [H]

Identifier: 113474749

GI number: 113474749

Start: 1488276

End: 1489448

Strand: Reverse

Name: dapL [H]

Synonym: Tery_0944

Alternate gene names: 113474749

Gene position: 1489448-1488276 (Counterclockwise)

Preceding gene: 113474750

Following gene: 113474744

Centisome position: 19.22

GC content: 40.75

Gene sequence:

>1173_bases
ATGCATTTATCAAAACGTTTAAAACCTTTAAGCTTTAATGTCTTTGCTGATATGGATAGGGCTAAGGGTAGGGCAAAGGC
AGCAGGACAAGATTTAATAGATTTGTCTTTAGGATCTTCTGATTTACCTGCGCCTCGTCACGCTTTAGAGGCGATATCTC
AATCTCTACAAGATTCTAATACTCATGGTTATTCATTATTTTCTAGCACTCAAGCTTTTAGGGAGGCAGTAGCTCGGTGG
TATAGTAATAAGTTTGACATTTCACTAAACCCGGAAACTGAAGTTTTAGCTTTAATTGGTTCCCAGGAAGGTACGGCCCA
TTTACCTTTGGCTATCCTGGATCCCGGAGATTTTGCTTTGCTGCAAGACCCTGGCTATCCTTCTCATAGTGGTGGGGTGT
ATTTGGCCGGAGGTCAGGTTTACCCCATGCCTTTATTAGCAGAAAATAAGTTTTTGCCTGTCTTGGGAGATATTCCTCAA
CATGTCTTGGCTCAGGCAAAAATGATGATTTTGAGTTATCCTCATAATCCCACAACGGCGATCGCTCCAATATCATTTCT
CCAAGAAGCTGTGGCTTTTTGCCAAAAACATAATTTGGTCTTGGTTCACGATGCTCCTTATCTGGATTTTGTTTTTAATT
CATCTTCTGAAGCTCCTTCTATTTTTCAAGCTGACGTAGAAAAAAGTGTTTCTATAGAATTTTTTACTATGTCTAAGTCT
TATAGTATGGGGGGTTTTCGTGTGGGCTATGCTATTGGTAATGCTCAGTTGATTCAAGCTTTACGACAGGTTAAAGCTTG
TATTGACTTTAATCAATATCGTGGCATTTTTAATGGGGCGATCGCAGCTTTAACTGGTCCCCAAGAGGTGGTCAGAAAAA
CTGTAGACATTTTTCGCCAACGGCGGGACATTTTTATTGAGGCATTGGATAATATTGGTTGGACTGTGCCAATGCCATCA
GCAACCATGTATGTTTGGACAAAGTTACCGAAATTATGGTCTAATGATTCTGTGGATTTCTGTGTAGATTTAGTGGAAAA
CACTGGGGTAGCAGTTGCCCCAGGGGCTGGTTTTGGTAAGGCGGGAGAAGGGTATGTGAGGTTTGCTTTAGTGCATAGAC
CAGAGGTTTTGTCAAGAGCTGTAGAGAAAATTTCTGTATTTTTACAAAGATAG

Upstream 100 bases:

>100_bases
TGTCAGATTGTATATAGTATGGTATTTTTAATATTTTTTGTTAATAAACAATAAGCCTTTTTGTTCATCTCCGTTTTTTT
CTTAGGAAAATTTAGTCAAA

Downstream 100 bases:

>100_bases
TTTAGTGAATTATATCGTTATTATTGGGGTGAGTTTAACCAAAAAACTAGATAAATGCTTTTCTCAAATTACTGAGGTAT
AGTTTATGTTCGTATGGGAT

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MHLSKRLKPLSFNVFADMDRAKGRAKAAGQDLIDLSLGSSDLPAPRHALEAISQSLQDSNTHGYSLFSSTQAFREAVARW
YSNKFDISLNPETEVLALIGSQEGTAHLPLAILDPGDFALLQDPGYPSHSGGVYLAGGQVYPMPLLAENKFLPVLGDIPQ
HVLAQAKMMILSYPHNPTTAIAPISFLQEAVAFCQKHNLVLVHDAPYLDFVFNSSSEAPSIFQADVEKSVSIEFFTMSKS
YSMGGFRVGYAIGNAQLIQALRQVKACIDFNQYRGIFNGAIAALTGPQEVVRKTVDIFRQRRDIFIEALDNIGWTVPMPS
ATMYVWTKLPKLWSNDSVDFCVDLVENTGVAVAPGAGFGKAGEGYVRFALVHRPEVLSRAVEKISVFLQR

Sequences:

>Translated_390_residues
MHLSKRLKPLSFNVFADMDRAKGRAKAAGQDLIDLSLGSSDLPAPRHALEAISQSLQDSNTHGYSLFSSTQAFREAVARW
YSNKFDISLNPETEVLALIGSQEGTAHLPLAILDPGDFALLQDPGYPSHSGGVYLAGGQVYPMPLLAENKFLPVLGDIPQ
HVLAQAKMMILSYPHNPTTAIAPISFLQEAVAFCQKHNLVLVHDAPYLDFVFNSSSEAPSIFQADVEKSVSIEFFTMSKS
YSMGGFRVGYAIGNAQLIQALRQVKACIDFNQYRGIFNGAIAALTGPQEVVRKTVDIFRQRRDIFIEALDNIGWTVPMPS
ATMYVWTKLPKLWSNDSVDFCVDLVENTGVAVAPGAGFGKAGEGYVRFALVHRPEVLSRAVEKISVFLQR
>Mature_390_residues
MHLSKRLKPLSFNVFADMDRAKGRAKAAGQDLIDLSLGSSDLPAPRHALEAISQSLQDSNTHGYSLFSSTQAFREAVARW
YSNKFDISLNPETEVLALIGSQEGTAHLPLAILDPGDFALLQDPGYPSHSGGVYLAGGQVYPMPLLAENKFLPVLGDIPQ
HVLAQAKMMILSYPHNPTTAIAPISFLQEAVAFCQKHNLVLVHDAPYLDFVFNSSSEAPSIFQADVEKSVSIEFFTMSKS
YSMGGFRVGYAIGNAQLIQALRQVKACIDFNQYRGIFNGAIAALTGPQEVVRKTVDIFRQRRDIFIEALDNIGWTVPMPS
ATMYVWTKLPKLWSNDSVDFCVDLVENTGVAVAPGAGFGKAGEGYVRFALVHRPEVLSRAVEKISVFLQR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=419, Percent_Identity=19.8090692124105, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI56713254, Length=419, Percent_Identity=19.8090692124105, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI95147551, Length=439, Percent_Identity=20.7289293849658, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI169881279, Length=439, Percent_Identity=20.7289293849658, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=38.1818181818182, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1786816, Length=392, Percent_Identity=23.9795918367347, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=21.2871287128713, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=257, Percent_Identity=25.6809338521401, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=257, Percent_Identity=25.6809338521401, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=337, Percent_Identity=21.6617210682493, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=20.7692307692308, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=24.2268041237113, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=24.2268041237113, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=24.2268041237113, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=24.2268041237113, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=23.2189973614776, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 42741; Mature: 42741

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSKRLKPLSFNVFADMDRAKGRAKAAGQDLIDLSLGSSDLPAPRHALEAISQSLQDSN
CCCHHHCCCCEEEEEECCHHHCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
THGYSLFSSTQAFREAVARWYSNKFDISLNPETEVLALIGSQEGTAHLPLAILDPGDFAL
CCCEEHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCCCCCEEEECCCCEEE
LQDPGYPSHSGGVYLAGGQVYPMPLLAENKFLPVLGDIPQHVLAQAKMMILSYPHNPTTA
EECCCCCCCCCCEEEECCEEECCCEECCCCCCCHHCCCHHHHHHHHHEEEEECCCCCCHH
IAPISFLQEAVAFCQKHNLVLVHDAPYLDFVFNSSSEAPSIFQADVEKSVSIEFFTMSKS
HHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEEECC
YSMGGFRVGYAIGNAQLIQALRQVKACIDFNQYRGIFNGAIAALTGPQEVVRKTVDIFRQ
CCCCCEEEEEEECCHHHHHHHHHHHHHHCHHHHCCHHHCHHEEECCHHHHHHHHHHHHHH
RRDIFIEALDNIGWTVPMPSATMYVWTKLPKLWSNDSVDFCVDLVENTGVAVAPGAGFGK
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHCCCEEEECCCCCCC
AGEGYVRFALVHRPEVLSRAVEKISVFLQR
CCCCEEEEEEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHLSKRLKPLSFNVFADMDRAKGRAKAAGQDLIDLSLGSSDLPAPRHALEAISQSLQDSN
CCCHHHCCCCEEEEEECCHHHCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
THGYSLFSSTQAFREAVARWYSNKFDISLNPETEVLALIGSQEGTAHLPLAILDPGDFAL
CCCEEHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCCCCCEEEECCCCEEE
LQDPGYPSHSGGVYLAGGQVYPMPLLAENKFLPVLGDIPQHVLAQAKMMILSYPHNPTTA
EECCCCCCCCCCEEEECCEEECCCEECCCCCCCHHCCCHHHHHHHHHEEEEECCCCCCHH
IAPISFLQEAVAFCQKHNLVLVHDAPYLDFVFNSSSEAPSIFQADVEKSVSIEFFTMSKS
HHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEEECC
YSMGGFRVGYAIGNAQLIQALRQVKACIDFNQYRGIFNGAIAALTGPQEVVRKTVDIFRQ
CCCCCEEEEEEECCHHHHHHHHHHHHHHCHHHHCCHHHCHHEEECCHHHHHHHHHHHHHH
RRDIFIEALDNIGWTVPMPSATMYVWTKLPKLWSNDSVDFCVDLVENTGVAVAPGAGFGK
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHCCCEEEECCCCCCC
AGEGYVRFALVHRPEVLSRAVEKISVFLQR
CCCCEEEEEEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA