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The map label for this gene is ilvE [H]

Identifier: 113474702

GI number: 113474702

Start: 1409261

End: 1410328

Strand: Direct

Name: ilvE [H]

Synonym: Tery_0889

Alternate gene names: 113474702

Gene position: 1409261-1410328 (Clockwise)

Preceding gene: 113474701

Following gene: 113474703

Centisome position: 18.18

GC content: 32.49

Gene sequence:

>1068_bases
ATGCAAATAGTTAATTCTCAAATATCTATAGAAAAAACTAGCCACTCTCGGATTAAAGAACAGGATATTAATAATACTCC
CTTTGGTAAAGTATTTAGCGATCATATGTTGGTTGCTACCTATGCAAATAATAGTTGGCAAGAGGTAAAAATTACTCCCT
ATGGTAATATTTCTATTCGTCCTTCTCTCTCTGTACTTCATTATGGTCAGGCAGTTTTTGAAGGTTTAAAAGCTTATAAA
AATTATCAGGGAAAACCTGTATTATTTCGGTTAGAAGCTAATTATAAAAGAATAAATAATTCAGCTTTTAGATTATGTAT
GCCATCCATTCCTAAAGAAATTTTTATAGATGGTTTAAAGGAATTAATTAGACTAGATACTGATTGGATTCCTACTAAAT
CAGATAGCGCATTATATATTCGACCTATTTATTTCGCTACAGATGAATCTGTCGGTCTCAAGCCTGCAAATAGTTATAAG
TTTATTATTTTGTCTTCCCCTACAGGTACATTTTATTCGGCACCAGTTAAGTTAATTGTTACAGATAAATATGTCCGAGC
TTCTGAAGGTGGAACTGGTGCAGCTAAATGTGCTGGGAATTATGCTGGTAGTTTTTTAGCAGATAAAGAAGCTAAAGAAC
AAGGTTATGATAATGTTTTATGGTTGGATGGAAAGGAAAAAAAATATATTGAAGAATGTGGTACGATGAATGTTGCTTTT
GTAATTAATGATGTTTTGATTACTCCTAAGTTGACAGGAAGTATATTAGGGGGAATTACTCGAGATAGTGCATTAACTTT
ATTTAGAGATATGGGTGTTAAAGTTGAGGAAAGATTAATCTCTATTGATGAGGTTGCAAAGGCTTATGAAGCAGGAAATA
TTTCTGAGGCTTTTGGTATGGGTACTGCTGCTACAATTGCTCATATTTCTGTTATTAACTATCAAGGTAAAGATATGATT
TTACCTCCTGTTGATGAACGAAAATATGCTTCTCAAGTTTTGCAAAAATTAGAAGATATTAAAACTGGTAAAGTCACTGA
CCCCTATGGTTGGATTTGTCAACTTTAA

Upstream 100 bases:

>100_bases
TTTTTTTTTAATATCACTAGATAAATTTGATTAGATGTATTTAACAGGGCATGATATTATAAAATATATAAAGTAGTTTT
TTACGAAAAGCCAGATAACA

Downstream 100 bases:

>100_bases
ATACTTGAATATTATATTAGTCTTGGGATGATATAGCTGAATTTAGAATTCATAATTTAGAAGCTATAAGCCAAAATTAA
AGAACATAAATTACTCAATA

Product: branched chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQIVNSQISIEKTSHSRIKEQDINNTPFGKVFSDHMLVATYANNSWQEVKITPYGNISIRPSLSVLHYGQAVFEGLKAYK
NYQGKPVLFRLEANYKRINNSAFRLCMPSIPKEIFIDGLKELIRLDTDWIPTKSDSALYIRPIYFATDESVGLKPANSYK
FIILSSPTGTFYSAPVKLIVTDKYVRASEGGTGAAKCAGNYAGSFLADKEAKEQGYDNVLWLDGKEKKYIEECGTMNVAF
VINDVLITPKLTGSILGGITRDSALTLFRDMGVKVEERLISIDEVAKAYEAGNISEAFGMGTAATIAHISVINYQGKDMI
LPPVDERKYASQVLQKLEDIKTGKVTDPYGWICQL

Sequences:

>Translated_355_residues
MQIVNSQISIEKTSHSRIKEQDINNTPFGKVFSDHMLVATYANNSWQEVKITPYGNISIRPSLSVLHYGQAVFEGLKAYK
NYQGKPVLFRLEANYKRINNSAFRLCMPSIPKEIFIDGLKELIRLDTDWIPTKSDSALYIRPIYFATDESVGLKPANSYK
FIILSSPTGTFYSAPVKLIVTDKYVRASEGGTGAAKCAGNYAGSFLADKEAKEQGYDNVLWLDGKEKKYIEECGTMNVAF
VINDVLITPKLTGSILGGITRDSALTLFRDMGVKVEERLISIDEVAKAYEAGNISEAFGMGTAATIAHISVINYQGKDMI
LPPVDERKYASQVLQKLEDIKTGKVTDPYGWICQL
>Mature_355_residues
MQIVNSQISIEKTSHSRIKEQDINNTPFGKVFSDHMLVATYANNSWQEVKITPYGNISIRPSLSVLHYGQAVFEGLKAYK
NYQGKPVLFRLEANYKRINNSAFRLCMPSIPKEIFIDGLKELIRLDTDWIPTKSDSALYIRPIYFATDESVGLKPANSYK
FIILSSPTGTFYSAPVKLIVTDKYVRASEGGTGAAKCAGNYAGSFLADKEAKEQGYDNVLWLDGKEKKYIEECGTMNVAF
VINDVLITPKLTGSILGGITRDSALTLFRDMGVKVEERLISIDEVAKAYEAGNISEAFGMGTAATIAHISVINYQGKDMI
LPPVDERKYASQVLQKLEDIKTGKVTDPYGWICQL

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI296010904, Length=345, Percent_Identity=38.8405797101449, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI38176287, Length=345, Percent_Identity=38.8405797101449, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI296010906, Length=345, Percent_Identity=38.8405797101449, Blast_Score=234, Evalue=6e-62,
Organism=Homo sapiens, GI50658084, Length=350, Percent_Identity=33.1428571428571, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI296010902, Length=345, Percent_Identity=35.0724637681159, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI296010900, Length=345, Percent_Identity=35.0724637681159, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI258614015, Length=284, Percent_Identity=33.8028169014084, Blast_Score=168, Evalue=9e-42,
Organism=Escherichia coli, GI48994963, Length=324, Percent_Identity=31.1728395061728, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17568601, Length=366, Percent_Identity=34.9726775956284, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI17565728, Length=357, Percent_Identity=33.0532212885154, Blast_Score=177, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6322002, Length=335, Percent_Identity=39.1044776119403, Blast_Score=216, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6322608, Length=357, Percent_Identity=35.5742296918768, Blast_Score=202, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24641779, Length=364, Percent_Identity=35.4395604395604, Blast_Score=228, Evalue=4e-60,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 39448; Mature: 39448

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIVNSQISIEKTSHSRIKEQDINNTPFGKVFSDHMLVATYANNSWQEVKITPYGNISIR
CCEECCEEEEEECHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCEEEEEEECCCCEEEC
PSLSVLHYGQAVFEGLKAYKNYQGKPVLFRLEANYKRINNSAFRLCMPSIPKEIFIDGLK
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHCCCCEEEEECCCCCHHHHHHHHH
ELIRLDTDWIPTKSDSALYIRPIYFATDESVGLKPANSYKFIILSSPTGTFYSAPVKLIV
HHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEECCEEEEE
TDKYVRASEGGTGAAKCAGNYAGSFLADKEAKEQGYDNVLWLDGKEKKYIEECGTMNVAF
EECEEEECCCCCCHHHHCCCCCCCHHCCCHHHHCCCCCEEEECCCCHHHHHHCCCCEEEE
VINDVLITPKLTGSILGGITRDSALTLFRDMGVKVEERLISIDEVAKAYEAGNISEAFGM
EEEEEEECCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCC
GTAATIAHISVINYQGKDMILPPVDERKYASQVLQKLEDIKTGKVTDPYGWICQL
CCHHHEEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEC
>Mature Secondary Structure
MQIVNSQISIEKTSHSRIKEQDINNTPFGKVFSDHMLVATYANNSWQEVKITPYGNISIR
CCEECCEEEEEECHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCEEEEEEECCCCEEEC
PSLSVLHYGQAVFEGLKAYKNYQGKPVLFRLEANYKRINNSAFRLCMPSIPKEIFIDGLK
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHCCCCEEEEECCCCCHHHHHHHHH
ELIRLDTDWIPTKSDSALYIRPIYFATDESVGLKPANSYKFIILSSPTGTFYSAPVKLIV
HHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEECCEEEEE
TDKYVRASEGGTGAAKCAGNYAGSFLADKEAKEQGYDNVLWLDGKEKKYIEECGTMNVAF
EECEEEECCCCCCHHHHCCCCCCCHHCCCHHHHCCCCCEEEECCCCHHHHHHCCCCEEEE
VINDVLITPKLTGSILGGITRDSALTLFRDMGVKVEERLISIDEVAKAYEAGNISEAFGM
EEEEEEECCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCC
GTAATIAHISVINYQGKDMILPPVDERKYASQVLQKLEDIKTGKVTDPYGWICQL
CCHHHEEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA