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The map label for this gene is 113474541

Identifier: 113474541

GI number: 113474541

Start: 1128295

End: 1129281

Strand: Direct

Name: 113474541

Synonym: Tery_0693

Alternate gene names: NA

Gene position: 1128295-1129281 (Clockwise)

Preceding gene: 113474540

Following gene: 113474543

Centisome position: 14.56

GC content: 38.7

Gene sequence:

>987_bases
TTGATCAGTCATGCTTATGATGAAGCAGCAGAAAAAGGGGACTTTCACAGTAAAATCGAACTGTGCAAACAAGAAGAAAT
TTTATGGGATACTGCACGGATAGAAGCACATTCACCAGAAAAACACGACTTTAATTCATGCCGCCCTCTCGACAGAAGTG
ACTTATCTCGCCAAGGTTGTGTTGAAATATATACCTTGGGTTTTGCAGTCATCAAAAATATGCCCTTATCAGAGTTAAAT
AATTTTCTCAGTAGTATTGGGCCAATTCCTTATACAGAGGGGGGACACTTCTATACGGTAAAATCTAAGCCAGCGGCTAA
TGACATAGCTGACACTGGGCACGCGCTACCTCCCTACACAGATTATGAAAGTTATATGTATGCTTCTCACCTACTGCAAT
TTCTTTACTTTAAAGCAACTAATGAAGATTCAACACTTGTAGATGGCTTTCGGGTAGCCCAAGATTTTCAAAAGCACCAC
CCAGACTATTTCCAAATTTTGGTAGAAACTCCTGCTCAGTTCCAGCAGTTTTACACAGAGTGGAAATATTATCACCGTCT
AGACTATTTCCAAATTTTGGTAGAAACTCCTGCTCAGTTCCAGCAGTTTTACACAGAGTGGAAATATTATCACCGTCGTA
GTCGCCGGATCATTGAATTAGACATAAAAGGGGAGGTTTCAGGAGTTTATTTTGGTAACTCCCACGCTTGTAATTGGGAT
ATTCCTTTTGACAAAATGGAAAAATTCTATGAGGCTTATAGTCAATTCTTCCGTTATTTGAAAAGTCCTGAATATCAGTA
TCATTTCCGTTCAGAAGCAGAAGACTGCCTAATGATTCAGAATTTTCAAGTGCTACATGGAAGAACAGCTTTTGATGCTA
ATTCTGGTTCGCGACATCTAGAGGTTTCTTATGTAGCTTGGAATTACTTTACAGGAAGAGAAATTTTTCGGCAGTTTCAA
CATTTGTACTTGAATGAGAATTATTAA

Upstream 100 bases:

>100_bases
AATATCTCCCAAACCTCTAAAGGTCCAGTTAACAGATAATGACCTGATTATAGACTGGGATGAAGAAACTCATCATCGCA
ATATTTTTCCTATTTCTTGG

Downstream 100 bases:

>100_bases
ATTAGATGATTTGAGAAGTTGGTTAATGAGGCATCAAAATGAGTATTTGGTAGATACCCACTATATAGAACCTATTTGGG
ATCTTTTTTTGCCGTTCAGG

Product: gamma-butyrobetaine,2-oxoglutarate dioxygenase

Products: NA

Alternate protein names: Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MISHAYDEAAEKGDFHSKIELCKQEEILWDTARIEAHSPEKHDFNSCRPLDRSDLSRQGCVEIYTLGFAVIKNMPLSELN
NFLSSIGPIPYTEGGHFYTVKSKPAANDIADTGHALPPYTDYESYMYASHLLQFLYFKATNEDSTLVDGFRVAQDFQKHH
PDYFQILVETPAQFQQFYTEWKYYHRLDYFQILVETPAQFQQFYTEWKYYHRRSRRIIELDIKGEVSGVYFGNSHACNWD
IPFDKMEKFYEAYSQFFRYLKSPEYQYHFRSEAEDCLMIQNFQVLHGRTAFDANSGSRHLEVSYVAWNYFTGREIFRQFQ
HLYLNENY

Sequences:

>Translated_328_residues
MISHAYDEAAEKGDFHSKIELCKQEEILWDTARIEAHSPEKHDFNSCRPLDRSDLSRQGCVEIYTLGFAVIKNMPLSELN
NFLSSIGPIPYTEGGHFYTVKSKPAANDIADTGHALPPYTDYESYMYASHLLQFLYFKATNEDSTLVDGFRVAQDFQKHH
PDYFQILVETPAQFQQFYTEWKYYHRLDYFQILVETPAQFQQFYTEWKYYHRRSRRIIELDIKGEVSGVYFGNSHACNWD
IPFDKMEKFYEAYSQFFRYLKSPEYQYHFRSEAEDCLMIQNFQVLHGRTAFDANSGSRHLEVSYVAWNYFTGREIFRQFQ
HLYLNENY
>Mature_328_residues
MISHAYDEAAEKGDFHSKIELCKQEEILWDTARIEAHSPEKHDFNSCRPLDRSDLSRQGCVEIYTLGFAVIKNMPLSELN
NFLSSIGPIPYTEGGHFYTVKSKPAANDIADTGHALPPYTDYESYMYASHLLQFLYFKATNEDSTLVDGFRVAQDFQKHH
PDYFQILVETPAQFQQFYTEWKYYHRLDYFQILVETPAQFQQFYTEWKYYHRRSRRIIELDIKGEVSGVYFGNSHACNWD
IPFDKMEKFYEAYSQFFRYLKSPEYQYHFRSEAEDCLMIQNFQVLHGRTAFDANSGSRHLEVSYVAWNYFTGREIFRQFQ
HLYLNENY

Specific function: Catalyzes the formation of L-carnitine from gamma- butyrobetaine [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-BBH/TMLD family [H]

Homologues:

Organism=Homo sapiens, GI4502369, Length=247, Percent_Identity=29.9595141700405, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17534641, Length=271, Percent_Identity=26.9372693726937, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639015, Length=249, Percent_Identity=27.710843373494, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221329931, Length=254, Percent_Identity=23.6220472440945, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012775
- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.1 [H]

Molecular weight: Translated: 39032; Mature: 39032

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHAYDEAAEKGDFHSKIELCKQEEILWDTARIEAHSPEKHDFNSCRPLDRSDLSRQGC
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHCCCCCC
VEIYTLGFAVIKNMPLSELNNFLSSIGPIPYTEGGHFYTVKSKPAANDIADTGHALPPYT
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCC
DYESYMYASHLLQFLYFKATNEDSTLVDGFRVAQDFQKHHPDYFQILVETPAQFQQFYTE
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHEEHHHHCHHHHHHHHHH
WKYYHRLDYFQILVETPAQFQQFYTEWKYYHRRSRRIIELDIKGEVSGVYFGNSHACNWD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEECCCCEECCC
IPFDKMEKFYEAYSQFFRYLKSPEYQYHFRSEAEDCLMIQNFQVLHGRTAFDANSGSRHL
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCEECCCEEECCCCCCCEE
EVSYVAWNYFTGREIFRQFQHLYLNENY
EEEEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MISHAYDEAAEKGDFHSKIELCKQEEILWDTARIEAHSPEKHDFNSCRPLDRSDLSRQGC
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHCCCCCC
VEIYTLGFAVIKNMPLSELNNFLSSIGPIPYTEGGHFYTVKSKPAANDIADTGHALPPYT
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCC
DYESYMYASHLLQFLYFKATNEDSTLVDGFRVAQDFQKHHPDYFQILVETPAQFQQFYTE
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHEEHHHHCHHHHHHHHHH
WKYYHRLDYFQILVETPAQFQQFYTEWKYYHRRSRRIIELDIKGEVSGVYFGNSHACNWD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEECCCCEECCC
IPFDKMEKFYEAYSQFFRYLKSPEYQYHFRSEAEDCLMIQNFQVLHGRTAFDANSGSRHL
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCEECCCEEECCCCCCCEE
EVSYVAWNYFTGREIFRQFQHLYLNENY
EEEEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]