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The map label for this gene is zwf [H]

Identifier: 113474533

GI number: 113474533

Start: 1117041

End: 1118570

Strand: Direct

Name: zwf [H]

Synonym: Tery_0684

Alternate gene names: 113474533

Gene position: 1117041-1118570 (Clockwise)

Preceding gene: 113474532

Following gene: 113474534

Centisome position: 14.41

GC content: 42.48

Gene sequence:

>1530_bases
ATGGTAGCAGTATTAGAAAATCCTCTGCGAGTTGGACTACAACAAGACCGGGTTCCAGAACCACAAATTATGATTATTTT
TGGTGCATCCGGTGATCTAACCCAGAGAAAACTTGTTCCAGCATTATATCAAATGAAGCTAGAACGGAGACTTCCTCCTG
AACTAACAATAGTGGGAGTTGCTCGCAGAGAATGGAGCCATGATTACTTCCGCGAACAAATGAAGATAGGTGTAGAAGAA
TTTGGTGGTGGCTTACAATCTGAAGAACTGTGGAATGATTTTGCTAAGGGGATTTTTTACTGCCCTGGTAATATAGATCA
ACCAGAAGATTATCAAAGACTCAAAAAACTTTTGAGTCAATTGGACGAAGAGAGAGGTACGCGAGGTAATCGCGTATTTT
ACTTGTCTGTAGCTCCCCGATACTTTGGAGAAGCAACCCAACAGTTAGGGGCAGCAGGAATGTTAGTTGATCCTAAAAAG
CAAAGATTAGTAATTGAAAAACCCTTTGGTAGAGACCTCAGTTCAGCTCAGGTACTCAATAAAATTGTGCGTCAAGTTTG
CCCCGAAGAGCAAATATACCGTATTGACCATTATCTAGGGAAAGAAACTGTTCAAAACTTAATGGTATTTAGATTTGCAA
ATGCTATTTTTGAACCTCTGTGGAACCGTCAATTTGTTGATAATGTCCAAATCACTGTTGCAGAAACGGTAGGGTTAGAA
GGACGTGCTGGATATTATGAAACATCAGGTGCATTGCGGGACATGGTACAAAACCACCTGATGCAGCTATTCTCCCTGAC
AGCAATGGAACCTCCTAATTCTTTAGATGCTGACAGTATTCGCAATGAAAAAGTAAAAGTAGTTCAGGCAACCCGCCTAG
CAAATTTAGAGCGTTTAGAATATTCAGCAATTCGTGGTCAGTATACACAGGGTTGGATGAAAGGTAAAAGTGTACCAGCT
TATCGGGAAGAGGGAGGAGCAAATCCTAACTCTACAACACCTACGTATGCAGCACTGAAACTCAATATTGATAATTGGCG
CTGGAAAGGGGTACCATTTTATTTGCGGACTGGCAAGCGAATGCCAAAAAAAGTCTCAGAAATTGCTATTCAGTTTAAAG
AAGTACCGTTTCTGATGTTTCAGTCAGCGGCAAAACAAGCGAATCCTAATGTCTTGGCTTTACGCATCCAGCCTAATGAA
GGGGTATCAATGCGTTTTGAAGTCAAAACACCAGGTAGTTCCCTGCGAACTCGCTCAGTAGATATGGATTTTCGTTACGA
TACTGCTTTTGGTAAGCCTAGTACAGATGCTTACAGTCGTTTGTTGGTTGACTGTATGTTAGGAGACCAAACCTTATTTA
CTCGTGGCGATGAAGTAGAAGCATCTTGGCGAGCATTAACACCAATACTTAGCATCTGGGATGCTCCTGCTCCACCAGAA
GTCATACCTTTGTATGAAGCAGGCACCTGGGGGCCAGTTGAGGCTGAACTGTTGCTCAACCAAGATGGTCGTCGTTGGCG
CCGACTTTGA

Upstream 100 bases:

>100_bases
ATAAAATTCGTTGCTATAAATCAAAAAAAAAGATACTTGGGCAAAAACAAAAGAGCTTCTATAGTAATCAATAGTAATCA
ATTAGAAGGAGTCAATATAG

Downstream 100 bases:

>100_bases
ATTAATTATCATTGATCCGGTTTTTACAGTAATGTCAAATAGGTTCGCTTATCCAAGGCTAACTACTGAAGTCAAAGTTG
AACATTCTGCAAAAAAGACC

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MVAVLENPLRVGLQQDRVPEPQIMIIFGASGDLTQRKLVPALYQMKLERRLPPELTIVGVARREWSHDYFREQMKIGVEE
FGGGLQSEELWNDFAKGIFYCPGNIDQPEDYQRLKKLLSQLDEERGTRGNRVFYLSVAPRYFGEATQQLGAAGMLVDPKK
QRLVIEKPFGRDLSSAQVLNKIVRQVCPEEQIYRIDHYLGKETVQNLMVFRFANAIFEPLWNRQFVDNVQITVAETVGLE
GRAGYYETSGALRDMVQNHLMQLFSLTAMEPPNSLDADSIRNEKVKVVQATRLANLERLEYSAIRGQYTQGWMKGKSVPA
YREEGGANPNSTTPTYAALKLNIDNWRWKGVPFYLRTGKRMPKKVSEIAIQFKEVPFLMFQSAAKQANPNVLALRIQPNE
GVSMRFEVKTPGSSLRTRSVDMDFRYDTAFGKPSTDAYSRLLVDCMLGDQTLFTRGDEVEASWRALTPILSIWDAPAPPE
VIPLYEAGTWGPVEAELLLNQDGRRWRRL

Sequences:

>Translated_509_residues
MVAVLENPLRVGLQQDRVPEPQIMIIFGASGDLTQRKLVPALYQMKLERRLPPELTIVGVARREWSHDYFREQMKIGVEE
FGGGLQSEELWNDFAKGIFYCPGNIDQPEDYQRLKKLLSQLDEERGTRGNRVFYLSVAPRYFGEATQQLGAAGMLVDPKK
QRLVIEKPFGRDLSSAQVLNKIVRQVCPEEQIYRIDHYLGKETVQNLMVFRFANAIFEPLWNRQFVDNVQITVAETVGLE
GRAGYYETSGALRDMVQNHLMQLFSLTAMEPPNSLDADSIRNEKVKVVQATRLANLERLEYSAIRGQYTQGWMKGKSVPA
YREEGGANPNSTTPTYAALKLNIDNWRWKGVPFYLRTGKRMPKKVSEIAIQFKEVPFLMFQSAAKQANPNVLALRIQPNE
GVSMRFEVKTPGSSLRTRSVDMDFRYDTAFGKPSTDAYSRLLVDCMLGDQTLFTRGDEVEASWRALTPILSIWDAPAPPE
VIPLYEAGTWGPVEAELLLNQDGRRWRRL
>Mature_509_residues
MVAVLENPLRVGLQQDRVPEPQIMIIFGASGDLTQRKLVPALYQMKLERRLPPELTIVGVARREWSHDYFREQMKIGVEE
FGGGLQSEELWNDFAKGIFYCPGNIDQPEDYQRLKKLLSQLDEERGTRGNRVFYLSVAPRYFGEATQQLGAAGMLVDPKK
QRLVIEKPFGRDLSSAQVLNKIVRQVCPEEQIYRIDHYLGKETVQNLMVFRFANAIFEPLWNRQFVDNVQITVAETVGLE
GRAGYYETSGALRDMVQNHLMQLFSLTAMEPPNSLDADSIRNEKVKVVQATRLANLERLEYSAIRGQYTQGWMKGKSVPA
YREEGGANPNSTTPTYAALKLNIDNWRWKGVPFYLRTGKRMPKKVSEIAIQFKEVPFLMFQSAAKQANPNVLALRIQPNE
GVSMRFEVKTPGSSLRTRSVDMDFRYDTAFGKPSTDAYSRLLVDCMLGDQTLFTRGDEVEASWRALTPILSIWDAPAPPE
VIPLYEAGTWGPVEAELLLNQDGRRWRRL

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=495, Percent_Identity=37.1717171717172, Blast_Score=311, Evalue=8e-85,
Organism=Homo sapiens, GI109389365, Length=495, Percent_Identity=37.1717171717172, Blast_Score=311, Evalue=9e-85,
Organism=Homo sapiens, GI52145310, Length=493, Percent_Identity=31.8458417849899, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI1788158, Length=490, Percent_Identity=41.8367346938776, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17538218, Length=511, Percent_Identity=38.5518590998043, Blast_Score=343, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6324088, Length=474, Percent_Identity=35.8649789029536, Blast_Score=290, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24643350, Length=487, Percent_Identity=37.3716632443532, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24643352, Length=487, Percent_Identity=37.3716632443532, Blast_Score=302, Evalue=4e-82,
Organism=Drosophila melanogaster, GI221513548, Length=482, Percent_Identity=31.1203319502075, Blast_Score=220, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 58024; Mature: 58024

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVLENPLRVGLQQDRVPEPQIMIIFGASGDLTQRKLVPALYQMKLERRLPPELTIVGV
CCEEECCHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
ARREWSHDYFREQMKIGVEEFGGGLQSEELWNDFAKGIFYCPGNIDQPEDYQRLKKLLSQ
HHHHCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHH
LDEERGTRGNRVFYLSVAPRYFGEATQQLGAAGMLVDPKKQRLVIEKPFGRDLSSAQVLN
HHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCCEECCCCCEEEEECCCCCCCHHHHHHH
KIVRQVCPEEQIYRIDHYLGKETVQNLMVFRFANAIFEPLWNRQFVDNVQITVAETVGLE
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEEECCCC
GRAGYYETSGALRDMVQNHLMQLFSLTAMEPPNSLDADSIRNEKVKVVQATRLANLERLE
CCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHH
YSAIRGQYTQGWMKGKSVPAYREEGGANPNSTTPTYAALKLNIDNWRWKGVPFYLRTGKR
HHHHCCCHHHHHHCCCCCCCHHHHCCCCCCCCCCCEEEEEEECCCEEECCCCEEEECCCC
MPKKVSEIAIQFKEVPFLMFQSAAKQANPNVLALRIQPNEGVSMRFEVKTPGSSLRTRSV
CHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEE
DMDFRYDTAFGKPSTDAYSRLLVDCMLGDQTLFTRGDEVEASWRALTPILSIWDAPAPPE
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
VIPLYEAGTWGPVEAELLLNQDGRRWRRL
EEEEEECCCCCCCEEEEEECCCCHHHHCC
>Mature Secondary Structure
MVAVLENPLRVGLQQDRVPEPQIMIIFGASGDLTQRKLVPALYQMKLERRLPPELTIVGV
CCEEECCHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
ARREWSHDYFREQMKIGVEEFGGGLQSEELWNDFAKGIFYCPGNIDQPEDYQRLKKLLSQ
HHHHCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHH
LDEERGTRGNRVFYLSVAPRYFGEATQQLGAAGMLVDPKKQRLVIEKPFGRDLSSAQVLN
HHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCCEECCCCCEEEEECCCCCCCHHHHHHH
KIVRQVCPEEQIYRIDHYLGKETVQNLMVFRFANAIFEPLWNRQFVDNVQITVAETVGLE
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEEECCCC
GRAGYYETSGALRDMVQNHLMQLFSLTAMEPPNSLDADSIRNEKVKVVQATRLANLERLE
CCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHH
YSAIRGQYTQGWMKGKSVPAYREEGGANPNSTTPTYAALKLNIDNWRWKGVPFYLRTGKR
HHHHCCCHHHHHHCCCCCCCHHHHCCCCCCCCCCCEEEEEEECCCEEECCCCEEEECCCC
MPKKVSEIAIQFKEVPFLMFQSAAKQANPNVLALRIQPNEGVSMRFEVKTPGSSLRTRSV
CHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEE
DMDFRYDTAFGKPSTDAYSRLLVDCMLGDQTLFTRGDEVEASWRALTPILSIWDAPAPPE
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
VIPLYEAGTWGPVEAELLLNQDGRRWRRL
EEEEEECCCCCCCEEEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1643289 [H]