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The map label for this gene is murQ

Identifier: 113474225

GI number: 113474225

Start: 522487

End: 523410

Strand: Reverse

Name: murQ

Synonym: Tery_0340

Alternate gene names: 113474225

Gene position: 523410-522487 (Counterclockwise)

Preceding gene: 113474226

Following gene: 113474223

Centisome position: 6.75

GC content: 39.72

Gene sequence:

>924_bases
ATGAAAAATTTACAACAGCGAGGTCATTTGTTAACCGAACAGGTTAACCCAAATAGTCATAATCTCGACCAGTTAAGTTC
TTTAGAATTAGTAGACTTGTTTAACCAAGAGGATAAGCAAACTTTGAAAGCGATCGCTTCATCCCGTTTACAACTAGCTC
AGGCAGTAGACATGACTACTAAAGCTTTAAGTCAAGGTGGTAAATTGTTTTATGTGGGAGCAGGTACTAGTGGTCGTTTA
GGCGTATTAGATGCCGCTGAATGTCCACCAACATTTTGCACGTCTCCAGAGTTGGTACAAGGAATTATTGCTGGAGGTGC
AAATGCTTTACTTCGCAGTTCCGAAGATTTGGAGGATAGCTGGGAAGATGGTAATGAGGCGATCGCTTCGCACAATATCA
CAAATCTAGACGTAATAGTTGGCATCACTGCAGGTGGTACAACTCCTTATGTTCACGGTGCTTTAGAAGGAGCAAAACAA
AGGGCAGCAAAAACAATTTTTATTACTTGTGTGCCTGTAGAACAATTTAGCATCAAGGTAGATGTAGATATTAGGTTGTT
GGTTGGTCCGGAACTATTATCAGGTTCAACCCGTCTGAAGGCAGGAACAGTCACAAAAATGGCCTTAAATATCTTATCCA
CCGGAGTAATGGTGAGGTTAGGAAAAGTTTATGGTAATCGCATGATTGATGTAGCTATAAAAAATAGTAAGTTACGGGAT
CGGGCCTTACGAATTATTGAAGACTTAACCGAGTTAAGTCGGGATGAAGCAGAGGAATTATTGAATAAAAGTGGTGATTC
AGTTAAGTTAGCACTTTTGATGCACTGGAGTAACTTAAAAAAAGAAGAAGGGGATAGGGTTTTATCTGAGTATCAAGGTA
ATCTTAGAGCAGCCATGAAAAACGTAAGTTTTTCTACTGAGTAG

Upstream 100 bases:

>100_bases
AATTAACACGATTTATACCCGAGTTTTAACACAATAATAGTTAAGAGATAAGATTTATGGAGACGCTAATATTTTTTTGT
ATAATTTGTCAAGGTTTGAT

Downstream 100 bases:

>100_bases
ACTACAAAGTGGGGAAATTCTATGTAATGTCTTAGAGGGGGTGATCATTTTTGAAAAGTTCCCGACAGAAAAACTACTAT
ATATTAGTTTCCATAGTATT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKNLQQRGHLLTEQVNPNSHNLDQLSSLELVDLFNQEDKQTLKAIASSRLQLAQAVDMTTKALSQGGKLFYVGAGTSGRL
GVLDAAECPPTFCTSPELVQGIIAGGANALLRSSEDLEDSWEDGNEAIASHNITNLDVIVGITAGGTTPYVHGALEGAKQ
RAAKTIFITCVPVEQFSIKVDVDIRLLVGPELLSGSTRLKAGTVTKMALNILSTGVMVRLGKVYGNRMIDVAIKNSKLRD
RALRIIEDLTELSRDEAEELLNKSGDSVKLALLMHWSNLKKEEGDRVLSEYQGNLRAAMKNVSFSTE

Sequences:

>Translated_307_residues
MKNLQQRGHLLTEQVNPNSHNLDQLSSLELVDLFNQEDKQTLKAIASSRLQLAQAVDMTTKALSQGGKLFYVGAGTSGRL
GVLDAAECPPTFCTSPELVQGIIAGGANALLRSSEDLEDSWEDGNEAIASHNITNLDVIVGITAGGTTPYVHGALEGAKQ
RAAKTIFITCVPVEQFSIKVDVDIRLLVGPELLSGSTRLKAGTVTKMALNILSTGVMVRLGKVYGNRMIDVAIKNSKLRD
RALRIIEDLTELSRDEAEELLNKSGDSVKLALLMHWSNLKKEEGDRVLSEYQGNLRAAMKNVSFSTE
>Mature_307_residues
MKNLQQRGHLLTEQVNPNSHNLDQLSSLELVDLFNQEDKQTLKAIASSRLQLAQAVDMTTKALSQGGKLFYVGAGTSGRL
GVLDAAECPPTFCTSPELVQGIIAGGANALLRSSEDLEDSWEDGNEAIASHNITNLDVIVGITAGGTTPYVHGALEGAKQ
RAAKTIFITCVPVEQFSIKVDVDIRLLVGPELLSGSTRLKAGTVTKMALNILSTGVMVRLGKVYGNRMIDVAIKNSKLRD
RALRIIEDLTELSRDEAEELLNKSGDSVKLALLMHWSNLKKEEGDRVLSEYQGNLRAAMKNVSFSTE

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=287, Percent_Identity=42.1602787456446, Blast_Score=229, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_TRIEI (Q119L1)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720286.1
- ProteinModelPortal:   Q119L1
- SMR:   Q119L1
- STRING:   Q119L1
- GeneID:   4242516
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0340
- NMPDR:   fig|203124.1.peg.2466
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   SMIGVGK
- PhylomeDB:   Q119L1
- ProtClustDB:   PRK05441
- BioCyc:   TERY203124:TERY_0340-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- TIGRFAMs:   TIGR00274

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33245; Mature: 33245

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 87-87 ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLQQRGHLLTEQVNPNSHNLDQLSSLELVDLFNQEDKQTLKAIASSRLQLAQAVDMTT
CCCHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KALSQGGKLFYVGAGTSGRLGVLDAAECPPTFCTSPELVQGIIAGGANALLRSSEDLEDS
HHHHCCCCEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCHHHH
WEDGNEAIASHNITNLDVIVGITAGGTTPYVHGALEGAKQRAAKTIFITCVPVEQFSIKV
HCCCCHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEEEHHHEEEEE
DVDIRLLVGPELLSGSTRLKAGTVTKMALNILSTGVMVRLGKVYGNRMIDVAIKNSKLRD
EEEEEEEECCHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHH
RALRIIEDLTELSRDEAEELLNKSGDSVKLALLMHWSNLKKEEGDRVLSEYQGNLRAAMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHH
NVSFSTE
HCCCCCC
>Mature Secondary Structure
MKNLQQRGHLLTEQVNPNSHNLDQLSSLELVDLFNQEDKQTLKAIASSRLQLAQAVDMTT
CCCHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KALSQGGKLFYVGAGTSGRLGVLDAAECPPTFCTSPELVQGIIAGGANALLRSSEDLEDS
HHHHCCCCEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCHHHH
WEDGNEAIASHNITNLDVIVGITAGGTTPYVHGALEGAKQRAAKTIFITCVPVEQFSIKV
HCCCCHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEEEHHHEEEEE
DVDIRLLVGPELLSGSTRLKAGTVTKMALNILSTGVMVRLGKVYGNRMIDVAIKNSKLRD
EEEEEEEECCHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHH
RALRIIEDLTELSRDEAEELLNKSGDSVKLALLMHWSNLKKEEGDRVLSEYQGNLRAAMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHH
NVSFSTE
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA