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The map label for this gene is arsR-1 [H]

Identifier: 110835541

GI number: 110835541

Start: 3026500

End: 3026817

Strand: Reverse

Name: arsR-1 [H]

Synonym: ABO_2680

Alternate gene names: 110835541

Gene position: 3026817-3026500 (Counterclockwise)

Preceding gene: 110835542

Following gene: 110835540

Centisome position: 97.01

GC content: 59.43

Gene sequence:

>318_bases
ATGCTCACACCTACTCAGCTCTGTAAATGCCTTGGCGATGATATCCGCCTCAGCCTGATCTGCTTGTTGCACGGTCAAGC
AGAGGTCTGCGTGTGTGATTTGGTCGATGCCATGCAGGCGCCACAATCTACCGTGTCCCGGCATCTTGCCCAGTTGCGCC
AGTGCGAACTGGTGGTCGCCCGGCGACAGGGCACCTGGATGCATTACCAGCTGAACCCGGCCTTGCCGGAGTGGGCTGCA
GCGGCCATTAATGCATTGGTAGTGCCCGCCCGAGATGCGTTGAATATCACTCTTCCCAGTGCCGCGTGCTGCGGCTGA

Upstream 100 bases:

>100_bases
GGTTATCGGATGGCCACAAACGGGCAGTGTTGCAGCTTGACCCTTAATGCTTGCCTCTATAATATCCGTATTTCCGAATA
TATGAATATACTATGCGCAC

Downstream 100 bases:

>100_bases
AAGACGAGAAAAGGTTATGAATACACCACTGAATGTCTTGTTTTTGTGCACCGGTAATTCCTGTCGCTCCATCATTGGTG
AAGCGCTGGCTGATCATCTG

Product: arsenic resistance transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MLTPTQLCKCLGDDIRLSLICLLHGQAEVCVCDLVDAMQAPQSTVSRHLAQLRQCELVVARRQGTWMHYQLNPALPEWAA
AAINALVVPARDALNITLPSAACCG

Sequences:

>Translated_105_residues
MLTPTQLCKCLGDDIRLSLICLLHGQAEVCVCDLVDAMQAPQSTVSRHLAQLRQCELVVARRQGTWMHYQLNPALPEWAA
AAINALVVPARDALNITLPSAACCG
>Mature_105_residues
MLTPTQLCKCLGDDIRLSLICLLHGQAEVCVCDLVDAMQAPQSTVSRHLAQLRQCELVVARRQGTWMHYQLNPALPEWAA
AAINALVVPARDALNITLPSAACCG

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=84, Percent_Identity=47.6190476190476, Blast_Score=87, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11366; Mature: 11366

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
10.5 %Cys+Met (Translated Protein)
7.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
10.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPTQLCKCLGDDIRLSLICLLHGQAEVCVCDLVDAMQAPQSTVSRHLAQLRQCELVVA
CCCHHHHHHHCCCCHHEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
RRQGTWMHYQLNPALPEWAAAAINALVVPARDALNITLPSAACCG
CCCCCEEEEEECCCCCHHHHHHHHHHEECCCCCEEEECCCCCCCC
>Mature Secondary Structure
MLTPTQLCKCLGDDIRLSLICLLHGQAEVCVCDLVDAMQAPQSTVSRHLAQLRQCELVVA
CCCHHHHHHHCCCCHHEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
RRQGTWMHYQLNPALPEWAAAAINALVVPARDALNITLPSAACCG
CCCCCEEEEEECCCCCHHHHHHHHHHEECCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]