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The map label for this gene is mmgC [H]

Identifier: 110835523

GI number: 110835523

Start: 3009704

End: 3010843

Strand: Reverse

Name: mmgC [H]

Synonym: ABO_2662

Alternate gene names: 110835523

Gene position: 3010843-3009704 (Counterclockwise)

Preceding gene: 110835524

Following gene: 110835521

Centisome position: 96.5

GC content: 54.39

Gene sequence:

>1140_bases
ATGCTTGATAAGAACGAAATCGAACTGTTTCGCGATAATGTAAAAAAATTCCTCGAAAACGAAGTGGCCCCCCATTACAA
CCAGTGGGAAAAAGCTGAGATATTCCCACGTGAACTGTGGAATAAAATGGGCGAAAACGGCTTGTTGTGTGTGGACGTAC
CAGAGGAATACGGCGGCTTTGGCGCCAACTTCCGCCTGTCAGCGGTGATCGTAGAGGAAGCCTCTCGCGCTGGTTTCAGT
TCCCTGGCCTCCAACATTTCTGTGCATTCCGACATCGTCGCTCCCTACATTCTGCACCTGGGCAATGAAGAGCAGAAAAA
AACCTGGTTGCCGAAAATGGTTACTGGTGAAGCCGTGGGGGCCATCGGCATGACCGAGCCTGGCGCTGGTTCCGACCTGC
AAGGCTTGAAAGCCCGTGCCGACAAGGATGGTGATGGCTATAGCATCAATGGCCAAAAAACCTTTATCACCAATGGTCAG
CATTGCGACGTGATCGTGCTGGCCACCAAGACCGACCCCAACGCTGGCTCCAAAGGCATGACGTTGTTCACCGTGGATTG
CACGCTGGACGGCTTTGCCCGTGGCCGCAACCTGGAGAAAATGGGCCTCCACGCGGCGGACACCTCTGAGCTATTTTTCG
AAAACGTAAAAGTTGGCGCCGAGCAGATACTGGGTGGTGAAGGCAAAGGCTTCGCCAACCTGATGAACGAGCTACCCCGC
GAGCGTCTGATTTTGGCGCTGGGCGCTGTCGCTGCTTGTGAAGGCATGATCGAGCGTACCATCGAATACACCAAAGAGCG
CATGGCGTTCGGCAAGCCTATTTCCAGCCTGCAGAATACCCGTTTCGTGCTGGCGGACTTACACGCCCAGGTGGTGATTA
ACCGTGCCTACTGCGAGCAGTGTATCGAGCAGTATGATCGCAGCGAACTCACCGCCACCAATGCTTCCATTGCCAAGCTC
ACCGCCACCGAGCTGCAAGGTGTGGTAGCCGACAAATGTCTGCAACTGTTCGGTGGCTACGGCTACATGCAGGAATACCC
GATTTCCCGCGACTACGTAGACGCCCGTATCCAGCGTATCTATGGCGGCACCAGTGAAATCATGAAAGAAATCATCTCCC
GGGATATCATCGGGCGGTAA

Upstream 100 bases:

>100_bases
ATAACCACACCGCACAATCGCCCCCCCGTGGGCTAACTAAAAATTGATGCCGGTGCGGTTGTGAATAGACCCCAAAACAG
GTTTCCAAGGACTAGCCAAC

Downstream 100 bases:

>100_bases
TTGTTTCTCTTCATGCTTTATAAAAAACGCGGCTTCGGCCGCGTTTTTTTATGGTGTCTTATATCTTATGTAGGAGCCCC
TCTAAAGGGCCTAACCGGCG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLDKNEIELFRDNVKKFLENEVAPHYNQWEKAEIFPRELWNKMGENGLLCVDVPEEYGGFGANFRLSAVIVEEASRAGFS
SLASNISVHSDIVAPYILHLGNEEQKKTWLPKMVTGEAVGAIGMTEPGAGSDLQGLKARADKDGDGYSINGQKTFITNGQ
HCDVIVLATKTDPNAGSKGMTLFTVDCTLDGFARGRNLEKMGLHAADTSELFFENVKVGAEQILGGEGKGFANLMNELPR
ERLILALGAVAACEGMIERTIEYTKERMAFGKPISSLQNTRFVLADLHAQVVINRAYCEQCIEQYDRSELTATNASIAKL
TATELQGVVADKCLQLFGGYGYMQEYPISRDYVDARIQRIYGGTSEIMKEIISRDIIGR

Sequences:

>Translated_379_residues
MLDKNEIELFRDNVKKFLENEVAPHYNQWEKAEIFPRELWNKMGENGLLCVDVPEEYGGFGANFRLSAVIVEEASRAGFS
SLASNISVHSDIVAPYILHLGNEEQKKTWLPKMVTGEAVGAIGMTEPGAGSDLQGLKARADKDGDGYSINGQKTFITNGQ
HCDVIVLATKTDPNAGSKGMTLFTVDCTLDGFARGRNLEKMGLHAADTSELFFENVKVGAEQILGGEGKGFANLMNELPR
ERLILALGAVAACEGMIERTIEYTKERMAFGKPISSLQNTRFVLADLHAQVVINRAYCEQCIEQYDRSELTATNASIAKL
TATELQGVVADKCLQLFGGYGYMQEYPISRDYVDARIQRIYGGTSEIMKEIISRDIIGR
>Mature_379_residues
MLDKNEIELFRDNVKKFLENEVAPHYNQWEKAEIFPRELWNKMGENGLLCVDVPEEYGGFGANFRLSAVIVEEASRAGFS
SLASNISVHSDIVAPYILHLGNEEQKKTWLPKMVTGEAVGAIGMTEPGAGSDLQGLKARADKDGDGYSINGQKTFITNGQ
HCDVIVLATKTDPNAGSKGMTLFTVDCTLDGFARGRNLEKMGLHAADTSELFFENVKVGAEQILGGEGKGFANLMNELPR
ERLILALGAVAACEGMIERTIEYTKERMAFGKPISSLQNTRFVLADLHAQVVINRAYCEQCIEQYDRSELTATNASIAKL
TATELQGVVADKCLQLFGGYGYMQEYPISRDYVDARIQRIYGGTSEIMKEIISRDIIGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=47.0588235294118, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=35.5013550135501, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=36.1764705882353, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=33.2432432432432, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=33.4239130434783, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=33.5120643431635, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=33.5120643431635, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI7656849, Length=370, Percent_Identity=31.0810810810811, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI21361497, Length=379, Percent_Identity=32.9815303430079, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4557235, Length=372, Percent_Identity=30.1075268817204, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI76496475, Length=372, Percent_Identity=30.1075268817204, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=28.0104712041885, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI7669494, Length=358, Percent_Identity=27.9329608938547, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI48976061, Length=292, Percent_Identity=28.0821917808219, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI211971008, Length=292, Percent_Identity=28.0821917808219, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38505218, Length=312, Percent_Identity=26.2820512820513, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=31.8302387267904, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786223, Length=376, Percent_Identity=24.7340425531915, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI87082384, Length=260, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=36.0742705570292, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17570075, Length=373, Percent_Identity=34.3163538873995, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17569725, Length=373, Percent_Identity=34.5844504021448, Blast_Score=214, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=35.6164383561644, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17508101, Length=362, Percent_Identity=31.2154696132597, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=32.6975476839237, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17505929, Length=368, Percent_Identity=31.25, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=30.5851063829787, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=30.8510638297872, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71990804, Length=279, Percent_Identity=34.0501792114695, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=348, Percent_Identity=30.4597701149425, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=32.8947368421053, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=369, Percent_Identity=27.6422764227642, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=30, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=281, Percent_Identity=30.2491103202847, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=24.4813278008299, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=31.8918918918919, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=33.245382585752, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=34.3915343915344, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=31.0810810810811, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24666513, Length=369, Percent_Identity=30.8943089430894, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI281363737, Length=349, Percent_Identity=31.8051575931232, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19920834, Length=377, Percent_Identity=29.1777188328912, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41773; Mature: 41773

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKNEIELFRDNVKKFLENEVAPHYNQWEKAEIFPRELWNKMGENGLLCVDVPEEYGGF
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHCCCCCEEEEECCHHHCCC
GANFRLSAVIVEEASRAGFSSLASNISVHSDIVAPYILHLGNEEQKKTWLPKMVTGEAVG
CCCEEEEEEEEHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHCCCHHC
AIGMTEPGAGSDLQGLKARADKDGDGYSINGQKTFITNGQHCDVIVLATKTDPNAGSKGM
CCCCCCCCCCCCCHHHHHHCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCC
TLFTVDCTLDGFARGRNLEKMGLHAADTSELFFENVKVGAEQILGGEGKGFANLMNELPR
EEEEEEEEEHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCH
ERLILALGAVAACEGMIERTIEYTKERMAFGKPISSLQNTRFVLADLHAQVVINRAYCEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEHHHHHHHHHHHHHHHHHH
CIEQYDRSELTATNASIAKLTATELQGVVADKCLQLFGGYGYMQEYPISRDYVDARIQRI
HHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHH
YGGTSEIMKEIISRDIIGR
HCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDKNEIELFRDNVKKFLENEVAPHYNQWEKAEIFPRELWNKMGENGLLCVDVPEEYGGF
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHCCCCCEEEEECCHHHCCC
GANFRLSAVIVEEASRAGFSSLASNISVHSDIVAPYILHLGNEEQKKTWLPKMVTGEAVG
CCCEEEEEEEEHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHCCCHHC
AIGMTEPGAGSDLQGLKARADKDGDGYSINGQKTFITNGQHCDVIVLATKTDPNAGSKGM
CCCCCCCCCCCCCHHHHHHCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCC
TLFTVDCTLDGFARGRNLEKMGLHAADTSELFFENVKVGAEQILGGEGKGFANLMNELPR
EEEEEEEEEHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCH
ERLILALGAVAACEGMIERTIEYTKERMAFGKPISSLQNTRFVLADLHAQVVINRAYCEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEHHHHHHHHHHHHHHHHHH
CIEQYDRSELTATNASIAKLTATELQGVVADKCLQLFGGYGYMQEYPISRDYVDARIQRI
HHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHH
YGGTSEIMKEIISRDIIGR
HCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]