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The map label for this gene is bigR [H]

Identifier: 110835496

GI number: 110835496

Start: 2983098

End: 2983415

Strand: Direct

Name: bigR [H]

Synonym: ABO_2635

Alternate gene names: 110835496

Gene position: 2983098-2983415 (Clockwise)

Preceding gene: 110835495

Following gene: 110835497

Centisome position: 95.61

GC content: 55.97

Gene sequence:

>318_bases
ATGACTACGATCGATCCCGACACCCTACGCGACAATGCCGTGCAAGCCAGCCAGCTACTGAAGGCGCTGTCTCACCCAGA
CCGGTTGATGCTGTTATGTCGCCTCGCAGAAGGCGAACGCAGCGTCAGTGAACTGGAACCCTTAGTGGGCGTTTACCAAC
CCTCACTCTCTCAGCAACTAGGCATTTTACGCCGCGAAGGGCTCGTTAGTAGCCGCCGGGAAGGCAAGCAAGTGTTCTAC
CAGGTTGCCAACCAGGATGCCCTGGCGGTACTGGAAGTACTGTATCAACGCTTCTGCGAGAACGGCAATGACTATTGA

Upstream 100 bases:

>100_bases
TGATCAGCCTTACAATACTTCAACAAAATTCGAAAAAAGCTTGAGGTCTGAATAGCAACAATATAATTTTTACTTAATTA
TATATTGTTGGATCCGCTCC

Downstream 100 bases:

>100_bases
TTGGAACAACTTTACGCCTTGGTCGTCATTAGCGGGTGGCGTTTTGATTGGCCTATCGGCTCTGCTGCTGCTGCATGCCA
ACGGTCGCATAGCCGGCATC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MTTIDPDTLRDNAVQASQLLKALSHPDRLMLLCRLAEGERSVSELEPLVGVYQPSLSQQLGILRREGLVSSRREGKQVFY
QVANQDALAVLEVLYQRFCENGNDY

Sequences:

>Translated_105_residues
MTTIDPDTLRDNAVQASQLLKALSHPDRLMLLCRLAEGERSVSELEPLVGVYQPSLSQQLGILRREGLVSSRREGKQVFY
QVANQDALAVLEVLYQRFCENGNDY
>Mature_104_residues
TTIDPDTLRDNAVQASQLLKALSHPDRLMLLCRLAEGERSVSELEPLVGVYQPSLSQQLGILRREGLVSSRREGKQVFYQ
VANQDALAVLEVLYQRFCENGNDY

Specific function: Represses an operon that comprises at least itself and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=92, Percent_Identity=36.9565217391304, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11837; Mature: 11705

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIDPDTLRDNAVQASQLLKALSHPDRLMLLCRLAEGERSVSELEPLVGVYQPSLSQQL
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHH
GILRREGLVSSRREGKQVFYQVANQDALAVLEVLYQRFCENGNDY
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTIDPDTLRDNAVQASQLLKALSHPDRLMLLCRLAEGERSVSELEPLVGVYQPSLSQQL
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHH
GILRREGLVSSRREGKQVFYQVANQDALAVLEVLYQRFCENGNDY
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]