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The map label for this gene is metX [H]

Identifier: 110835437

GI number: 110835437

Start: 2916998

End: 2918200

Strand: Direct

Name: metX [H]

Synonym: ABO_2576

Alternate gene names: 110835437

Gene position: 2916998-2918200 (Clockwise)

Preceding gene: 110835434

Following gene: 110835438

Centisome position: 93.49

GC content: 58.85

Gene sequence:

>1203_bases
ATGTCGCCACAGAATCCGGACGCCTTGCCCCACACCGCCGCCGACTCCGTAGGGTTGGTCGAGCCACAGGTGCATCACTT
CGACACCCCGTTGGAGCTGGAGTGTGGGCGCACGCTGCCCACCTATGACCTGATTTACGAAACCTATGGCACCCTCAACA
GCGACGCATCCAACGCAGTGCTGATCTGCCATGCCTTGTCCGGCCATCATCACGCGGCGGGCTATCATCGGGCAGACGAC
AAGCGCCCGGGCTGGTGGGATACCTGTATCGGCCCCGGTAAAGTCATCGATACCAACCGCTTCTTCGTCGTCAGCCTGAA
TAACCTTGGCGGCTGCCACGGCTCCACCGGCCCCGCCTCCATCAACCCGGAAAGCGGCCAGCCCTGGGGCCCCGATTTTC
CCATGATGACAGTGAAAGACTGGGTGAACAGCCAGGCCCGCCTCGCCGATGTGCTAGGCATTCAACGCTGGGCGGCAGTG
ATTGGCGGCAGCATGGGCGGCATGCAGGCGCTGCAGTGGTCCATCGATTACCCAGAACGGCTCAGCCATGCGGTAGTGAT
CGCCGCCGCGCCCAAATTGTCGGCCCAAAACATTGCCTTCAACGAAGTGGCGCGACAATCCATTCTGACCGACCCGAATT
TCTACGGTGGGCGTTATTACCTGCACGATACCTACCCTCGGCAAGGGCTGATTCTGGCGCGTATGGTAGGCCACATCACC
TACCTGAGTGACGACGCCATGCGCATGAAGTTCGGCCGCGACCTGCGCGCCGGGCGCTTCCATTTCGGCTTCGACGTGGA
ATTTCAGGTCGAATCCTACTTGCGCCATCAGGGCGAAGTCTTTTCTCGCAACTTCGACGCCAACACCTACTTGCTGATGA
CCAAAGCATTGGATTATTTCGATCCAGCTCGGGAATTCGACCATTCGCTGGAGCAGGCTTTAAGCAAGCCCACCTGTAAT
TTTCTGGTGATGTCATTCACCTCCGACTGGCGTTTTGCCCCAGAGCGCAGCCGAGAAATCGTCAACGGCTTAGTCCACGC
CGGTCGTAATGTGAGCTACGCCGAGATCGATACGCCCAAGGGCCACGACGCCTTTTTGCTGGATATTCCCGAGTACATAA
AGCTGTTCGGTGCCTACATGCACAGGGTTGCCAACGAGACAGAGAATAAATCGCAAGCTGTAGAGGCCGCCCCCCATGCG
TGA

Upstream 100 bases:

>100_bases
TGTGTTTGATCAGCAGGATACCATGACAACTGCCGTGCTTTGATTGCGCGTCCACCGGGCTGGCTTTAGACTTTGCGACA
TCTCTTGCTAGCGAGTCATC

Downstream 100 bases:

>100_bases
TGACCTTCAACTAATCAGCGACTGGATCCCGCACAATGCCACCCTGCTGGATCTAGGCTGCGGCGACGGCACTCTGCTAG
CGCATTTGAAAACACACAAA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSPQNPDALPHTAADSVGLVEPQVHHFDTPLELECGRTLPTYDLIYETYGTLNSDASNAVLICHALSGHHHAAGYHRADD
KRPGWWDTCIGPGKVIDTNRFFVVSLNNLGGCHGSTGPASINPESGQPWGPDFPMMTVKDWVNSQARLADVLGIQRWAAV
IGGSMGGMQALQWSIDYPERLSHAVVIAAAPKLSAQNIAFNEVARQSILTDPNFYGGRYYLHDTYPRQGLILARMVGHIT
YLSDDAMRMKFGRDLRAGRFHFGFDVEFQVESYLRHQGEVFSRNFDANTYLLMTKALDYFDPAREFDHSLEQALSKPTCN
FLVMSFTSDWRFAPERSREIVNGLVHAGRNVSYAEIDTPKGHDAFLLDIPEYIKLFGAYMHRVANETENKSQAVEAAPHA

Sequences:

>Translated_400_residues
MSPQNPDALPHTAADSVGLVEPQVHHFDTPLELECGRTLPTYDLIYETYGTLNSDASNAVLICHALSGHHHAAGYHRADD
KRPGWWDTCIGPGKVIDTNRFFVVSLNNLGGCHGSTGPASINPESGQPWGPDFPMMTVKDWVNSQARLADVLGIQRWAAV
IGGSMGGMQALQWSIDYPERLSHAVVIAAAPKLSAQNIAFNEVARQSILTDPNFYGGRYYLHDTYPRQGLILARMVGHIT
YLSDDAMRMKFGRDLRAGRFHFGFDVEFQVESYLRHQGEVFSRNFDANTYLLMTKALDYFDPAREFDHSLEQALSKPTCN
FLVMSFTSDWRFAPERSREIVNGLVHAGRNVSYAEIDTPKGHDAFLLDIPEYIKLFGAYMHRVANETENKSQAVEAAPHA
>Mature_399_residues
SPQNPDALPHTAADSVGLVEPQVHHFDTPLELECGRTLPTYDLIYETYGTLNSDASNAVLICHALSGHHHAAGYHRADDK
RPGWWDTCIGPGKVIDTNRFFVVSLNNLGGCHGSTGPASINPESGQPWGPDFPMMTVKDWVNSQARLADVLGIQRWAAVI
GGSMGGMQALQWSIDYPERLSHAVVIAAAPKLSAQNIAFNEVARQSILTDPNFYGGRYYLHDTYPRQGLILARMVGHITY
LSDDAMRMKFGRDLRAGRFHFGFDVEFQVESYLRHQGEVFSRNFDANTYLLMTKALDYFDPAREFDHSLEQALSKPTCNF
LVMSFTSDWRFAPERSREIVNGLVHAGRNVSYAEIDTPKGHDAFLLDIPEYIKLFGAYMHRVANETENKSQAVEAAPHA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=224, Percent_Identity=38.8392857142857, Blast_Score=161, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 44633; Mature: 44501

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPQNPDALPHTAADSVGLVEPQVHHFDTPLELECGRTLPTYDLIYETYGTLNSDASNAV
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEE
LICHALSGHHHAAGYHRADDKRPGWWDTCIGPGKVIDTNRFFVVSLNNLGGCHGSTGPAS
EEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEECCCEEEEEECCCCCCCCCCCCCC
INPESGQPWGPDFPMMTVKDWVNSQARLADVLGIQRWAAVIGGSMGGMQALQWSIDYPER
CCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHH
LSHAVVIAAAPKLSAQNIAFNEVARQSILTDPNFYGGRYYLHDTYPRQGLILARMVGHIT
HCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
YLSDDAMRMKFGRDLRAGRFHFGFDVEFQVESYLRHQGEVFSRNFDANTYLLMTKALDYF
EECCCHHHHHHCCCCCCCEEEECCEEEEHHHHHHHHCCHHHHCCCCCCEEEEEEHHHHHC
DPAREFDHSLEQALSKPTCNFLVMSFTSDWRFAPERSREIVNGLVHAGRNVSYAEIDTPK
CHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
GHDAFLLDIPEYIKLFGAYMHRVANETENKSQAVEAAPHA
CCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
SPQNPDALPHTAADSVGLVEPQVHHFDTPLELECGRTLPTYDLIYETYGTLNSDASNAV
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEE
LICHALSGHHHAAGYHRADDKRPGWWDTCIGPGKVIDTNRFFVVSLNNLGGCHGSTGPAS
EEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEECCCEEEEEECCCCCCCCCCCCCC
INPESGQPWGPDFPMMTVKDWVNSQARLADVLGIQRWAAVIGGSMGGMQALQWSIDYPER
CCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHH
LSHAVVIAAAPKLSAQNIAFNEVARQSILTDPNFYGGRYYLHDTYPRQGLILARMVGHIT
HCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
YLSDDAMRMKFGRDLRAGRFHFGFDVEFQVESYLRHQGEVFSRNFDANTYLLMTKALDYF
EECCCHHHHHHCCCCCCCEEEECCEEEEHHHHHHHHCCHHHHCCCCCCEEEEEEHHHHHC
DPAREFDHSLEQALSKPTCNFLVMSFTSDWRFAPERSREIVNGLVHAGRNVSYAEIDTPK
CHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
GHDAFLLDIPEYIKLFGAYMHRVANETENKSQAVEAAPHA
CCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA