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The map label for this gene is rho [H]

Identifier: 110835324

GI number: 110835324

Start: 2789211

End: 2790470

Strand: Direct

Name: rho [H]

Synonym: ABO_2463

Alternate gene names: 110835324

Gene position: 2789211-2790470 (Clockwise)

Preceding gene: 110835323

Following gene: 110835325

Centisome position: 89.39

GC content: 56.19

Gene sequence:

>1260_bases
ATGAATCTTTCTGAACTGAAGCAGAAGCCGATTGGAGAACTTCTGGACATTGCCAAGGAACTCGGTCTCGAGAACCTGGC
AAGAACCCGTAAACAAGACGTTATCTTTTCCATCCTTAAACGCGCCGCCAAAAATGGCTCCGACATTTACGGCGATGGCG
TGCTGGAAATCCTGCAGGATGGTTTCGGTTTCCTTCGTTCCGCTGAAGGATCTTATCTTGCCGGCCCGGACGACATTTAC
GTTTCGCCCAGCCAGATCCGTCGCTTCAATTTACGCACCGGCGACACCATCGCCGGAAAAATCCGGCCCCCCAAGGATGG
CGAGCGTTACTTCGCCATGCTCAAGGTCAACGAGATCAACTTTGACCGCCCGGAAAACGCCAAGAACAAAATCCTGTTCG
AGAACCTGACCCCGCTGTTTCCTACTCAGCGATTGGTCATGGAAATCGGTAATGGCTCCACCGAAGACATTACCACTCGG
GTAATCGATCTGGTGGCACCCATCGGTAAAGGGCAGCGTGGCCTAATCGTCGCGCCGCCCAAAGCCGGTAAGACCATGCT
GCTGCAGAGCGTGGCCCAGTCCATTGCCCGCAACAACCCCGAAACTCACATGATTGTGCTGCTCATCGACGAGCGCCCGG
AAGAAGTGACAGAAATGTCCCGAACCGTGCGCGGTGAAGTGGTGGCCTCCACCTTTGACGAGCCACCGGCCCGTCACGTT
CAGGTGGCTGAAATGGTGATCGAGAAAGCCAAGCGGCTGGTCGAGCACAAACAGGACGTGGTAATCCTGCTGGACTCCAT
CACCCGTCTGGCGCGCGCCTACAACACCGTGCAGCCCAGCTCCGGCAAGGTGCTCACCGGTGGTGTTGACGCCCACGCCC
TGGAAAAGCCCAAGCGCTTTTTCGGTGCCGCGCGGAACATCGAGGAAGGCGGTAGCCTGACCATCCTCGCCACCGCTCTG
GTCGACACCGGTTCCAAAATGGACGAAGTGATCTACGAGGAATTCAAAGGCACCGGCAACATGGAACTGCATCTGGACCG
CAAGGTGGCAGAGAAGCGTGTGTTCCCGGCCATGAATATCCGCAAATCCGGCACCCGTCGTGAAGAACGTCTGGTGAGCG
AAGACGAACTGCAGAAGATGTGGATCCTGCGCAAGGTGCTGCACCCCATGGACGAAATTGGCGCCATGGAATTCCTCATC
GACCGCATGAAGCAGACCAAGACAAACCTGGAATTCTTCGATTCCATGAAGCGCAAATAA

Upstream 100 bases:

>100_bases
TTGCCGGGCCAGATTCCGAAAAAACCGGATTATCAAAACAACTGCAACACTGCGGTGGTGCATCCTCTCAATTCATCCAA
AGACACCAAATTAGACGCCA

Downstream 100 bases:

>100_bases
GCGGCGCAACGCGCCGCACGCTTCAAGCAACATGCAAAACCCCGCTTCGGCGGGGTTTTTGTTATCCGCCACCGGCGCTT
GCCTGCCGATCAGCGGCTAC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNLSELKQKPIGELLDIAKELGLENLARTRKQDVIFSILKRAAKNGSDIYGDGVLEILQDGFGFLRSAEGSYLAGPDDIY
VSPSQIRRFNLRTGDTIAGKIRPPKDGERYFAMLKVNEINFDRPENAKNKILFENLTPLFPTQRLVMEIGNGSTEDITTR
VIDLVAPIGKGQRGLIVAPPKAGKTMLLQSVAQSIARNNPETHMIVLLIDERPEEVTEMSRTVRGEVVASTFDEPPARHV
QVAEMVIEKAKRLVEHKQDVVILLDSITRLARAYNTVQPSSGKVLTGGVDAHALEKPKRFFGAARNIEEGGSLTILATAL
VDTGSKMDEVIYEEFKGTGNMELHLDRKVAEKRVFPAMNIRKSGTRREERLVSEDELQKMWILRKVLHPMDEIGAMEFLI
DRMKQTKTNLEFFDSMKRK

Sequences:

>Translated_419_residues
MNLSELKQKPIGELLDIAKELGLENLARTRKQDVIFSILKRAAKNGSDIYGDGVLEILQDGFGFLRSAEGSYLAGPDDIY
VSPSQIRRFNLRTGDTIAGKIRPPKDGERYFAMLKVNEINFDRPENAKNKILFENLTPLFPTQRLVMEIGNGSTEDITTR
VIDLVAPIGKGQRGLIVAPPKAGKTMLLQSVAQSIARNNPETHMIVLLIDERPEEVTEMSRTVRGEVVASTFDEPPARHV
QVAEMVIEKAKRLVEHKQDVVILLDSITRLARAYNTVQPSSGKVLTGGVDAHALEKPKRFFGAARNIEEGGSLTILATAL
VDTGSKMDEVIYEEFKGTGNMELHLDRKVAEKRVFPAMNIRKSGTRREERLVSEDELQKMWILRKVLHPMDEIGAMEFLI
DRMKQTKTNLEFFDSMKRK
>Mature_419_residues
MNLSELKQKPIGELLDIAKELGLENLARTRKQDVIFSILKRAAKNGSDIYGDGVLEILQDGFGFLRSAEGSYLAGPDDIY
VSPSQIRRFNLRTGDTIAGKIRPPKDGERYFAMLKVNEINFDRPENAKNKILFENLTPLFPTQRLVMEIGNGSTEDITTR
VIDLVAPIGKGQRGLIVAPPKAGKTMLLQSVAQSIARNNPETHMIVLLIDERPEEVTEMSRTVRGEVVASTFDEPPARHV
QVAEMVIEKAKRLVEHKQDVVILLDSITRLARAYNTVQPSSGKVLTGGVDAHALEKPKRFFGAARNIEEGGSLTILATAL
VDTGSKMDEVIYEEFKGTGNMELHLDRKVAEKRVFPAMNIRKSGTRREERLVSEDELQKMWILRKVLHPMDEIGAMEFLI
DRMKQTKTNLEFFDSMKRK

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=418, Percent_Identity=78.4688995215311, Blast_Score=695, Evalue=0.0,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 47040; Mature: 47040

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSELKQKPIGELLDIAKELGLENLARTRKQDVIFSILKRAAKNGSDIYGDGVLEILQD
CCHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
GFGFLRSAEGSYLAGPDDIYVSPSQIRRFNLRTGDTIAGKIRPPKDGERYFAMLKVNEIN
HHHHHCCCCCCCCCCCCCEEECHHHHHEECCCCCCEEECCCCCCCCCCEEEEEEEEECCC
FDRPENAKNKILFENLTPLFPTQRLVMEIGNGSTEDITTRVIDLVAPIGKGQRGLIVAPP
CCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEECC
KAGKTMLLQSVAQSIARNNPETHMIVLLIDERPEEVTEMSRTVRGEVVASTFDEPPARHV
CCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
QVAEMVIEKAKRLVEHKQDVVILLDSITRLARAYNTVQPSSGKVLTGGVDAHALEKPKRF
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHH
FGAARNIEEGGSLTILATALVDTGSKMDEVIYEEFKGTGNMELHLDRKVAEKRVFPAMNI
HHHHCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCC
RKSGTRREERLVSEDELQKMWILRKVLHPMDEIGAMEFLIDRMKQTKTNLEFFDSMKRK
CCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLSELKQKPIGELLDIAKELGLENLARTRKQDVIFSILKRAAKNGSDIYGDGVLEILQD
CCHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
GFGFLRSAEGSYLAGPDDIYVSPSQIRRFNLRTGDTIAGKIRPPKDGERYFAMLKVNEIN
HHHHHCCCCCCCCCCCCCEEECHHHHHEECCCCCCEEECCCCCCCCCCEEEEEEEEECCC
FDRPENAKNKILFENLTPLFPTQRLVMEIGNGSTEDITTRVIDLVAPIGKGQRGLIVAPP
CCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEECC
KAGKTMLLQSVAQSIARNNPETHMIVLLIDERPEEVTEMSRTVRGEVVASTFDEPPARHV
CCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
QVAEMVIEKAKRLVEHKQDVVILLDSITRLARAYNTVQPSSGKVLTGGVDAHALEKPKRF
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHH
FGAARNIEEGGSLTILATALVDTGSKMDEVIYEEFKGTGNMELHLDRKVAEKRVFPAMNI
HHHHCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCC
RKSGTRREERLVSEDELQKMWILRKVLHPMDEIGAMEFLIDRMKQTKTNLEFFDSMKRK
CCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]