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The map label for this gene is hflX [H]

Identifier: 110835063

GI number: 110835063

Start: 2513446

End: 2514888

Strand: Reverse

Name: hflX [H]

Synonym: ABO_2202

Alternate gene names: 110835063

Gene position: 2514888-2513446 (Counterclockwise)

Preceding gene: 110835064

Following gene: 110835062

Centisome position: 80.6

GC content: 54.61

Gene sequence:

>1443_bases
ATGCATTTCCTGCCTTTCCACCACCTTCCTGGTTTAAACTGGGGGTACCTGTCCCCATATCCGCATCCTATGGACTTATT
TGATCGTACAGAACAAACACGCACCGAAGCCGGCGAGCGCGCTATTTTGGTTCATCTGGAGCTGCCTGATGCTATGGGGC
GTGAAGATCTGGATGAATTCCATCATTTGGTGACCTCCAGCGGTGTCCTGCCTGTTATCCAGCTGACGGGCAAACGAGAC
CGGCCTGATCCAGCATTATTTATCGGCACTGGAAAAACCGATGAATTGGCGGCCATGGTAAGTGAGCACCAGGCTGATGT
GGTGCTGTTTAATCATGCCCTTAGTCCGGGTCAGGAACGTAATCTGGAACGGGTAGTGAAATGCAGGGTGCTGGACCGCA
CCGGTTTGATTCTGGATATCTTTGCTCAGCGGGCTCGAACCCATGAAGGGCGCTTGCAGGTGGAGTTGGCGCAACTTCGC
CACTTGTCATCTCGGTTGGTGAGAGGCTGGACCCACCTGGAGCGTCAAAAAGGCGGTATTGGCCTGCGCGGCCCTGGTGA
GACACAACTGGAAACGGATCGCCGTTTATTGCGTGATCGTATTCGCGGAATCGAATCGCGATTGGAAAAAGTGCGTAAGC
AGCGCGCTCAAGGGCGTCGCGCCCGGCAACGGTCGGAAACTCCGCTAATTTCTCTGGTAGGTTATACCAATGCGGGCAAG
TCGACCCTGTTCAATGCCATTACTACGGGTGATGTGTATGTGGCAGACCAATTGTTTGCTACCTTGGACCCGACGTTGCG
CAAAGTAAAAGTGCCGGGTGTAGGGCCGGCCATTTTGGCAGATACCGTGGGTTTTATCCGGCATTTGCCGCACCGGTTGG
TGCAGGCATTTCGAGCCACGCTTGAAGAAACCGTGAACGCTAACCTGTTGCTGCACGTGACTGACTGTAGTGCGGAAGAG
CGGGACAATAATGTGGTTGCTGTGAATGAGGTGCTGGAAGAAATTGGTGGCGATAAGCTACCGGTGCTGCATGTTTATAA
CAAGGTCGATAATCTGGACCAGCCTCCCCGACTGGAGCGTGATGAACACGGCCAGCCTTGGCGAGTGTGGGTTTCTGCGC
AAACTGGCGATGGGTTCGATCTGCTGTTTGACGCGATCGCAGAGCGGTTGGCTGCTGGTTGGGTGGATTGCTGGGTGCGG
CTGCCCGCTTCAGCGGGGCGTCTGCGCGCTCGTTTGCACGAAGCCGGCGAAGTGCTTGAAGAGCAAACCGGCAACAATGG
CGATATGTTGCTGCGTGTTAATGTGAATCGGGTGCATTTTGAACGCCTGCTTCGCGAACAAGGTTTAAAAGAGGAAGAGC
TGGTAATTCCGGCACCTGCGGTTGCAGCTGAGGACGCCCCTTCCTACAATTCGGAACACTCGACAAACGCGAGTCATCAT
TAG

Upstream 100 bases:

>100_bases
TGACCGATTCCAGCCCCTATCCTTTGGGAGGGGCTGGACGCTTGTATAAGCAGTGAGATGGCTAGAATCATGTTGTTCTT
TCTCATCCAAGAAGAACACG

Downstream 100 bases:

>100_bases
GCTGGAGCCCTTTGGCTTTGGCGGACTGGAGATCTACATGGCGTGGAATGAACCCGGCGGCAATAAGCCGAAGGACCCTT
GGGGTGGTGGTGGCGACCAG

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MHFLPFHHLPGLNWGYLSPYPHPMDLFDRTEQTRTEAGERAILVHLELPDAMGREDLDEFHHLVTSSGVLPVIQLTGKRD
RPDPALFIGTGKTDELAAMVSEHQADVVLFNHALSPGQERNLERVVKCRVLDRTGLILDIFAQRARTHEGRLQVELAQLR
HLSSRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRIRGIESRLEKVRKQRAQGRRARQRSETPLISLVGYTNAGK
STLFNAITTGDVYVADQLFATLDPTLRKVKVPGVGPAILADTVGFIRHLPHRLVQAFRATLEETVNANLLLHVTDCSAEE
RDNNVVAVNEVLEEIGGDKLPVLHVYNKVDNLDQPPRLERDEHGQPWRVWVSAQTGDGFDLLFDAIAERLAAGWVDCWVR
LPASAGRLRARLHEAGEVLEEQTGNNGDMLLRVNVNRVHFERLLREQGLKEEELVIPAPAVAAEDAPSYNSEHSTNASHH

Sequences:

>Translated_480_residues
MHFLPFHHLPGLNWGYLSPYPHPMDLFDRTEQTRTEAGERAILVHLELPDAMGREDLDEFHHLVTSSGVLPVIQLTGKRD
RPDPALFIGTGKTDELAAMVSEHQADVVLFNHALSPGQERNLERVVKCRVLDRTGLILDIFAQRARTHEGRLQVELAQLR
HLSSRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRIRGIESRLEKVRKQRAQGRRARQRSETPLISLVGYTNAGK
STLFNAITTGDVYVADQLFATLDPTLRKVKVPGVGPAILADTVGFIRHLPHRLVQAFRATLEETVNANLLLHVTDCSAEE
RDNNVVAVNEVLEEIGGDKLPVLHVYNKVDNLDQPPRLERDEHGQPWRVWVSAQTGDGFDLLFDAIAERLAAGWVDCWVR
LPASAGRLRARLHEAGEVLEEQTGNNGDMLLRVNVNRVHFERLLREQGLKEEELVIPAPAVAAEDAPSYNSEHSTNASHH
>Mature_480_residues
MHFLPFHHLPGLNWGYLSPYPHPMDLFDRTEQTRTEAGERAILVHLELPDAMGREDLDEFHHLVTSSGVLPVIQLTGKRD
RPDPALFIGTGKTDELAAMVSEHQADVVLFNHALSPGQERNLERVVKCRVLDRTGLILDIFAQRARTHEGRLQVELAQLR
HLSSRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRIRGIESRLEKVRKQRAQGRRARQRSETPLISLVGYTNAGK
STLFNAITTGDVYVADQLFATLDPTLRKVKVPGVGPAILADTVGFIRHLPHRLVQAFRATLEETVNANLLLHVTDCSAEE
RDNNVVAVNEVLEEIGGDKLPVLHVYNKVDNLDQPPRLERDEHGQPWRVWVSAQTGDGFDLLFDAIAERLAAGWVDCWVR
LPASAGRLRARLHEAGEVLEEQTGNNGDMLLRVNVNRVHFERLLREQGLKEEELVIPAPAVAAEDAPSYNSEHSTNASHH

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=195, Percent_Identity=40.5128205128205, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310133116, Length=193, Percent_Identity=40.4145077720207, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310124269, Length=175, Percent_Identity=41.7142857142857, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI310124267, Length=175, Percent_Identity=41.7142857142857, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI310124171, Length=175, Percent_Identity=41.7142857142857, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI310124169, Length=175, Percent_Identity=41.7142857142857, Blast_Score=122, Evalue=1e-27,
Organism=Escherichia coli, GI1790615, Length=415, Percent_Identity=59.5180722891566, Blast_Score=478, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17561038, Length=319, Percent_Identity=29.153605015674, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24650079, Length=352, Percent_Identity=31.25, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 53930; Mature: 53930

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFLPFHHLPGLNWGYLSPYPHPMDLFDRTEQTRTEAGERAILVHLELPDAMGREDLDEF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHH
HHLVTSSGVLPVIQLTGKRDRPDPALFIGTGKTDELAAMVSEHQADVVLFNHALSPGQER
HHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCHHC
NLERVVKCRVLDRTGLILDIFAQRARTHEGRLQVELAQLRHLSSRLVRGWTHLERQKGGI
CHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
GLRGPGETQLETDRRLLRDRIRGIESRLEKVRKQRAQGRRARQRSETPLISLVGYTNAGK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
STLFNAITTGDVYVADQLFATLDPTLRKVKVPGVGPAILADTVGFIRHLPHRLVQAFRAT
HHHHHHHCCCCCHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LEETVNANLLLHVTDCSAEERDNNVVAVNEVLEEIGGDKLPVLHVYNKVDNLDQPPRLER
HHHHCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
DEHGQPWRVWVSAQTGDGFDLLFDAIAERLAAGWVDCWVRLPASAGRLRARLHEAGEVLE
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EQTGNNGDMLLRVNVNRVHFERLLREQGLKEEELVIPAPAVAAEDAPSYNSEHSTNASHH
HHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHFLPFHHLPGLNWGYLSPYPHPMDLFDRTEQTRTEAGERAILVHLELPDAMGREDLDEF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHH
HHLVTSSGVLPVIQLTGKRDRPDPALFIGTGKTDELAAMVSEHQADVVLFNHALSPGQER
HHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCHHC
NLERVVKCRVLDRTGLILDIFAQRARTHEGRLQVELAQLRHLSSRLVRGWTHLERQKGGI
CHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
GLRGPGETQLETDRRLLRDRIRGIESRLEKVRKQRAQGRRARQRSETPLISLVGYTNAGK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
STLFNAITTGDVYVADQLFATLDPTLRKVKVPGVGPAILADTVGFIRHLPHRLVQAFRAT
HHHHHHHCCCCCHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LEETVNANLLLHVTDCSAEERDNNVVAVNEVLEEIGGDKLPVLHVYNKVDNLDQPPRLER
HHHHCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
DEHGQPWRVWVSAQTGDGFDLLFDAIAERLAAGWVDCWVRLPASAGRLRARLHEAGEVLE
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EQTGNNGDMLLRVNVNRVHFERLLREQGLKEEELVIPAPAVAAEDAPSYNSEHSTNASHH
HHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]