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The map label for this gene is hflC [H]

Identifier: 110835061

GI number: 110835061

Start: 2511172

End: 2512236

Strand: Reverse

Name: hflC [H]

Synonym: ABO_2200

Alternate gene names: 110835061

Gene position: 2512236-2511172 (Counterclockwise)

Preceding gene: 110835062

Following gene: 110835060

Centisome position: 80.52

GC content: 54.08

Gene sequence:

>1065_bases
ATGAATAATCGTGGATGGATGGCGCTACTGGCCTTGGGCGTGCTGGCTCTTTTGGCGATGGACTCTTTTTTCATCGTAAA
CCAGAAAGAAAAGGTCGTGCTCAAGCAGTTTAGTCGGATCGAGAAGACCGATATCCAGCCTGGTCTTTACTTCAAGTGGC
CTATGGTGGAAGAAGTGGTGAAAGTGGATGGGCGTGCGTTGGTCTATGACGTACCTACCCAGTCTTTCCTTACCGCTGAG
AAAAAACTGCTGAATGTTGATGCCTTTGTTATTTGGCGCATCAGTAATGTGCAGCGTTACATCGTTAGTGTGGGGGGCGG
TTCTTCCAATCCTCAGGTAATGGAGCGCCGTGCTCGTGAACTGCTGGACCCTCGTGTGAACGAAGGCCTGCGCAACGAGT
TCGCTTCACGTACCGTCTTTCAGGTGGTGGCCGGCGAAAGTGACGTGGAAAAGGTGGAGGGCGATACGGCTATCCTCCGT
GACCCGACCACTGGCGAAACCGTGGAAGTGCCCACCGACCAACTGGATGAGTCGGTGTTGCGTGGAGCGGGAGCCGGTCA
GCAAGAGGGGAGTGAGCCTGCTGTAGATAGTGTGGCCAATGATCAACGTGAGGCGTTGATGGATCAGGTTCGCGCTGAAG
TAAACAAGTCGACCTTGGAAGATCTGGGTATTGAAGTGGTGGATATCCGTGTTAAACAGGTGGACTGGCCGGAACAGGTT
CGCGGGCGAGTATTCGACCGTATGCGCGCTGAGCGTCAGCGAGATGCTGCGGCTCATCGTTCACAGGGTCGTGAAGAAGC
GGAAAAAATCCGTGCCTCTGCAGACCGCCAGCGCACTGAAACATTGGCCCAGTCGTACCGTAAGGCTCAGAGCGCTCGCG
GTGAAGGGGATGCGCAGGCAGCGGCAATCTATGCCGAAGCCTACAATCAGGATAAAGAATTTTTCCGTTTCTACCGTAGC
TTGAGAGCCTATAAGGAAAGTTTCGATCAGCCGGAAGATGTGCTAATCCTGGAGCCGGATAGCGACTTTTTCCGCTACAT
GAAAGGGGCGAAGGGCGCGCCTTAA

Upstream 100 bases:

>100_bases
CAGCGTCCAGCACCACCTCCAGCGCCGGTGCGGATGACGGCGGCAGCGGACGTAGTAGCGGCCGCAGCTTGTACAACAAC
CGTAACCAGGAGCTGCGCTA

Downstream 100 bases:

>100_bases
TAGGGCCTTTTGTTCAAATAGCGTCTGGTTTGCCCCTGCGGCACCGGGCCTATCACAGAGCCCCGCCTAGTGCGGGGCTT
TTGTTGTTTGTTTTATCGAT

Product: protease subunit HflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNNRGWMALLALGVLALLAMDSFFIVNQKEKVVLKQFSRIEKTDIQPGLYFKWPMVEEVVKVDGRALVYDVPTQSFLTAE
KKLLNVDAFVIWRISNVQRYIVSVGGGSSNPQVMERRARELLDPRVNEGLRNEFASRTVFQVVAGESDVEKVEGDTAILR
DPTTGETVEVPTDQLDESVLRGAGAGQQEGSEPAVDSVANDQREALMDQVRAEVNKSTLEDLGIEVVDIRVKQVDWPEQV
RGRVFDRMRAERQRDAAAHRSQGREEAEKIRASADRQRTETLAQSYRKAQSARGEGDAQAAAIYAEAYNQDKEFFRFYRS
LRAYKESFDQPEDVLILEPDSDFFRYMKGAKGAP

Sequences:

>Translated_354_residues
MNNRGWMALLALGVLALLAMDSFFIVNQKEKVVLKQFSRIEKTDIQPGLYFKWPMVEEVVKVDGRALVYDVPTQSFLTAE
KKLLNVDAFVIWRISNVQRYIVSVGGGSSNPQVMERRARELLDPRVNEGLRNEFASRTVFQVVAGESDVEKVEGDTAILR
DPTTGETVEVPTDQLDESVLRGAGAGQQEGSEPAVDSVANDQREALMDQVRAEVNKSTLEDLGIEVVDIRVKQVDWPEQV
RGRVFDRMRAERQRDAAAHRSQGREEAEKIRASADRQRTETLAQSYRKAQSARGEGDAQAAAIYAEAYNQDKEFFRFYRS
LRAYKESFDQPEDVLILEPDSDFFRYMKGAKGAP
>Mature_354_residues
MNNRGWMALLALGVLALLAMDSFFIVNQKEKVVLKQFSRIEKTDIQPGLYFKWPMVEEVVKVDGRALVYDVPTQSFLTAE
KKLLNVDAFVIWRISNVQRYIVSVGGGSSNPQVMERRARELLDPRVNEGLRNEFASRTVFQVVAGESDVEKVEGDTAILR
DPTTGETVEVPTDQLDESVLRGAGAGQQEGSEPAVDSVANDQREALMDQVRAEVNKSTLEDLGIEVVDIRVKQVDWPEQV
RGRVFDRMRAERQRDAAAHRSQGREEAEKIRASADRQRTETLAQSYRKAQSARGEGDAQAAAIYAEAYNQDKEFFRFYRS
LRAYKESFDQPEDVLILEPDSDFFRYMKGAKGAP

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=341, Percent_Identity=38.1231671554252, Blast_Score=212, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 39976; Mature: 39976

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRGWMALLALGVLALLAMDSFFIVNQKEKVVLKQFSRIEKTDIQPGLYFKWPMVEEVV
CCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHH
KVDGRALVYDVPTQSFLTAEKKLLNVDAFVIWRISNVQRYIVSVGGGSSNPQVMERRARE
HCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHEEEEEEECCCCCCHHHHHHHHHH
LLDPRVNEGLRNEFASRTVFQVVAGESDVEKVEGDTAILRDPTTGETVEVPTDQLDESVL
HHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCCEEECCHHHHHHHHH
RGAGAGQQEGSEPAVDSVANDQREALMDQVRAEVNKSTLEDLGIEVVDIRVKQVDWPEQV
HCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
RGRVFDRMRAERQRDAAAHRSQGREEAEKIRASADRQRTETLAQSYRKAQSARGEGDAQA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
AAIYAEAYNQDKEFFRFYRSLRAYKESFDQPEDVLILEPDSDFFRYMKGAKGAP
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNRGWMALLALGVLALLAMDSFFIVNQKEKVVLKQFSRIEKTDIQPGLYFKWPMVEEVV
CCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHH
KVDGRALVYDVPTQSFLTAEKKLLNVDAFVIWRISNVQRYIVSVGGGSSNPQVMERRARE
HCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHEEEEEEECCCCCCHHHHHHHHHH
LLDPRVNEGLRNEFASRTVFQVVAGESDVEKVEGDTAILRDPTTGETVEVPTDQLDESVL
HHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCCEEECCHHHHHHHHH
RGAGAGQQEGSEPAVDSVANDQREALMDQVRAEVNKSTLEDLGIEVVDIRVKQVDWPEQV
HCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
RGRVFDRMRAERQRDAAAHRSQGREEAEKIRASADRQRTETLAQSYRKAQSARGEGDAQA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
AAIYAEAYNQDKEFFRFYRSLRAYKESFDQPEDVLILEPDSDFFRYMKGAKGAP
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]