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The map label for this gene is pgpA [H]

Identifier: 110835029

GI number: 110835029

Start: 2478329

End: 2478814

Strand: Reverse

Name: pgpA [H]

Synonym: ABO_2168

Alternate gene names: 110835029

Gene position: 2478814-2478329 (Counterclockwise)

Preceding gene: 110835030

Following gene: 110835028

Centisome position: 79.45

GC content: 57.41

Gene sequence:

>486_bases
ATGGAATTGAAGCGCCCCAAAATGAGTAATCCGGTGCACTTTTTGGCCTTTGGCTTTGGCTCCGGGCTGGCGCCGATTGC
GCCTGGCACTTTTGGCACGGTGGCGGCGATGCCCATTTGGTGGCTGTGTGCCCAGCTACCACTGTGGGGGTATTTGGCGG
TAACCGCCGCAGTGATTGCAGTGGGGCCTTACCTGTGCGGTAAGACCTCGGATGATATGCATGTGCATGATCACCCAGGC
ATTGTATGGGATGAGATTGCCGGCCTGTTAATTACCATGATAGCGGTGCCGATCACGCTTTGGGGAGCGCTGGCCGGGTT
TGTCGCGTTCCGAGTCTTCGACATTATCAAGCCTTGGCCTATTGGCTGGTTGGATCGACGGGTGGCGGGAGGTCTGGGCA
TCATGGTGGATGACCTGCTGGCCGGGGTGTATGCCGCCGTGGTAGTACAGCTGTTGATTTGGCAATTGCCCACCCTGTTT
ACCTGA

Upstream 100 bases:

>100_bases
GGGTGGCAGCATTTTTAACAGCGCGCAACACGCACATAGCTACACGCTAAAAAGCATATAATCCAAAGAAACTGCCAAGA
CCGAGCCCGCGAGGAATAAA

Downstream 100 bases:

>100_bases
TATCGTTTTGTCACTACCGTTGGCACTAAAAGGATAGCGCTGCTGATGGTTAGCTTTTAGCCTGAAGGAAGCTTTAATAG
TAAAGGATTGACGATGTTAG

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MELKRPKMSNPVHFLAFGFGSGLAPIAPGTFGTVAAMPIWWLCAQLPLWGYLAVTAAVIAVGPYLCGKTSDDMHVHDHPG
IVWDEIAGLLITMIAVPITLWGALAGFVAFRVFDIIKPWPIGWLDRRVAGGLGIMVDDLLAGVYAAVVVQLLIWQLPTLF
T

Sequences:

>Translated_161_residues
MELKRPKMSNPVHFLAFGFGSGLAPIAPGTFGTVAAMPIWWLCAQLPLWGYLAVTAAVIAVGPYLCGKTSDDMHVHDHPG
IVWDEIAGLLITMIAVPITLWGALAGFVAFRVFDIIKPWPIGWLDRRVAGGLGIMVDDLLAGVYAAVVVQLLIWQLPTLF
T
>Mature_161_residues
MELKRPKMSNPVHFLAFGFGSGLAPIAPGTFGTVAAMPIWWLCAQLPLWGYLAVTAAVIAVGPYLCGKTSDDMHVHDHPG
IVWDEIAGLLITMIAVPITLWGALAGFVAFRVFDIIKPWPIGWLDRRVAGGLGIMVDDLLAGVYAAVVVQLLIWQLPTLF
T

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=150, Percent_Identity=53.3333333333333, Blast_Score=156, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 17408; Mature: 17408

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKRPKMSNPVHFLAFGFGSGLAPIAPGTFGTVAAMPIWWLCAQLPLWGYLAVTAAVIA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VGPYLCGKTSDDMHVHDHPGIVWDEIAGLLITMIAVPITLWGALAGFVAFRVFDIIKPWP
HHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGWLDRRVAGGLGIMVDDLLAGVYAAVVVQLLIWQLPTLFT
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELKRPKMSNPVHFLAFGFGSGLAPIAPGTFGTVAAMPIWWLCAQLPLWGYLAVTAAVIA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VGPYLCGKTSDDMHVHDHPGIVWDEIAGLLITMIAVPITLWGALAGFVAFRVFDIIKPWP
HHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGWLDRRVAGGLGIMVDDLLAGVYAAVVVQLLIWQLPTLFT
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]