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The map label for this gene is folE2 [H]

Identifier: 110835005

GI number: 110835005

Start: 2450123

End: 2451094

Strand: Reverse

Name: folE2 [H]

Synonym: ABO_2144

Alternate gene names: 110835005

Gene position: 2451094-2450123 (Counterclockwise)

Preceding gene: 110835006

Following gene: 110835004

Centisome position: 78.56

GC content: 52.57

Gene sequence:

>972_bases
ATGGAGAATCCCATGACTCGTGACAACGGTGCCGGTAGCACCAAACAGATGCCGGATGTGGCGTCTAACTCCATGGTGGA
TCATATTCACACCACCCTAGATTGGGTGGGTATGAGTGAGATCCACTTGCCTGCTCGCGTCAGCGATACCTTGGCTGGCG
AACGTCCGGTGAGCACTTCTATTCAGGCCTATGTGAATTTGGCCAATGCGGATGCCAAAGGCATTCACATGTCGCGTCTG
TTCCTGATGCTGGAAGAGACCTTTGGTGACCATTCGGTCAGTGCGGGCTCCATTGAGCAACTACTGCGTAATTTCTTGCA
GACCCATGAGGGCCTCAGCACACGCGGTTTTGTACAGCTCGACTTTGAGTATTCCATGCGCCGCGCAGCCTTGAAGAGCA
GCTATTCCGGTTGGAAAAGTTACCCGGTCAGTATTAAAGGCACCCTGTGTGAAGATGGCATGCGCATTGAGTTATCGGTG
GAAGTGCCGTATTCCTCTACCTGCCCTTGTTCGGCAGCCCTGTCTCGACAGTTGATTCAGGAGCAATTTCGGAAAGATTT
TGAAGAAAGTAAAGTGGACACCGATGCGGTATTAGAATGGCTTGGCACGGAAGAGGGTATTCTTGCTACTCCTCACAGCC
AGCGTTCAATTGCGCAAGTGCGTGTTTTGCTTGATCACAATGTTGGTGATGCCTTTCCTATCACCGCATTGATTGATTCT
ATTGAAGGTGCTCTGAAGACGCCGGTGCAGACTGCGGTGAAGCGGGTGGACGAGCAGGAGTTCGCGCTGTTGAACGGCCA
GAACCTGATGTTCTGTGAAGATGCGGCCCGCCGCTTGAAGACCGCGCTGAACCCGCAGTCGTGTTACAAGGATTTCTGGT
TGCGTGTGAATCACCTGGAAAGCCTTCACGCCCATAATGCGGTCGCCATTGTGACCAAGGAAGTGGAGGGTGGTTACCTA
CCCATTCCTTGA

Upstream 100 bases:

>100_bases
TTTCTGCTAGACTTGCCCCCCTTGTATGAGCGGGCGATGACGAACAGATTACCGTTTCGTTCACCTGGGCAGCCTTACCT
TGGCTGTTTTCAGTGCCCCT

Downstream 100 bases:

>100_bases
TTGAGAAAGGCGGTTGGCAATACGCGGTGCATGCAGCACACAAAAAAAGCCCCCCTTCCCCTGTTGGAAGGGGGGCTTTT
TTTGTGTTTACCTGACTTAT

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MENPMTRDNGAGSTKQMPDVASNSMVDHIHTTLDWVGMSEIHLPARVSDTLAGERPVSTSIQAYVNLANADAKGIHMSRL
FLMLEETFGDHSVSAGSIEQLLRNFLQTHEGLSTRGFVQLDFEYSMRRAALKSSYSGWKSYPVSIKGTLCEDGMRIELSV
EVPYSSTCPCSAALSRQLIQEQFRKDFEESKVDTDAVLEWLGTEEGILATPHSQRSIAQVRVLLDHNVGDAFPITALIDS
IEGALKTPVQTAVKRVDEQEFALLNGQNLMFCEDAARRLKTALNPQSCYKDFWLRVNHLESLHAHNAVAIVTKEVEGGYL
PIP

Sequences:

>Translated_323_residues
MENPMTRDNGAGSTKQMPDVASNSMVDHIHTTLDWVGMSEIHLPARVSDTLAGERPVSTSIQAYVNLANADAKGIHMSRL
FLMLEETFGDHSVSAGSIEQLLRNFLQTHEGLSTRGFVQLDFEYSMRRAALKSSYSGWKSYPVSIKGTLCEDGMRIELSV
EVPYSSTCPCSAALSRQLIQEQFRKDFEESKVDTDAVLEWLGTEEGILATPHSQRSIAQVRVLLDHNVGDAFPITALIDS
IEGALKTPVQTAVKRVDEQEFALLNGQNLMFCEDAARRLKTALNPQSCYKDFWLRVNHLESLHAHNAVAIVTKEVEGGYL
PIP
>Mature_323_residues
MENPMTRDNGAGSTKQMPDVASNSMVDHIHTTLDWVGMSEIHLPARVSDTLAGERPVSTSIQAYVNLANADAKGIHMSRL
FLMLEETFGDHSVSAGSIEQLLRNFLQTHEGLSTRGFVQLDFEYSMRRAALKSSYSGWKSYPVSIKGTLCEDGMRIELSV
EVPYSSTCPCSAALSRQLIQEQFRKDFEESKVDTDAVLEWLGTEEGILATPHSQRSIAQVRVLLDHNVGDAFPITALIDS
IEGALKTPVQTAVKRVDEQEFALLNGQNLMFCEDAARRLKTALNPQSCYKDFWLRVNHLESLHAHNAVAIVTKEVEGGYL
PIP

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 35811; Mature: 35811

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENPMTRDNGAGSTKQMPDVASNSMVDHIHTTLDWVGMSEIHLPARVSDTLAGERPVSTS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHCCCCCCCHH
IQAYVNLANADAKGIHMSRLFLMLEETFGDHSVSAGSIEQLLRNFLQTHEGLSTRGFVQL
HHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
DFEYSMRRAALKSSYSGWKSYPVSIKGTLCEDGMRIELSVEVPYSSTCPCSAALSRQLIQ
EHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHH
EQFRKDFEESKVDTDAVLEWLGTEEGILATPHSQRSIAQVRVLLDHNVGDAFPITALIDS
HHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
IEGALKTPVQTAVKRVDEQEFALLNGQNLMFCEDAARRLKTALNPQSCYKDFWLRVNHLE
HHHHHCCHHHHHHHHHCHHHHHEECCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SLHAHNAVAIVTKEVEGGYLPIP
HHHCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MENPMTRDNGAGSTKQMPDVASNSMVDHIHTTLDWVGMSEIHLPARVSDTLAGERPVSTS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHCCCCCCCHH
IQAYVNLANADAKGIHMSRLFLMLEETFGDHSVSAGSIEQLLRNFLQTHEGLSTRGFVQL
HHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
DFEYSMRRAALKSSYSGWKSYPVSIKGTLCEDGMRIELSVEVPYSSTCPCSAALSRQLIQ
EHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHH
EQFRKDFEESKVDTDAVLEWLGTEEGILATPHSQRSIAQVRVLLDHNVGDAFPITALIDS
HHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
IEGALKTPVQTAVKRVDEQEFALLNGQNLMFCEDAARRLKTALNPQSCYKDFWLRVNHLE
HHHHHCCHHHHHHHHHCHHHHHEECCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SLHAHNAVAIVTKEVEGGYLPIP
HHHCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA