| Definition | Alcanivorax borkumensis SK2 chromosome, complete genome. |
|---|---|
| Accession | NC_008260 |
| Length | 3,120,143 |
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The map label for this gene is mrcA [H]
Identifier: 110834939
GI number: 110834939
Start: 2362059
End: 2364641
Strand: Reverse
Name: mrcA [H]
Synonym: ABO_2078
Alternate gene names: 110834939
Gene position: 2364641-2362059 (Counterclockwise)
Preceding gene: 110834940
Following gene: 110834927
Centisome position: 75.79
GC content: 62.49
Gene sequence:
>2583_bases ATGCGCTTCCCCCCCTGGATCCGATACCTGCTCCTTCTCCTGATCGCCGGCACCGGTGGTGGCCTGTCCATCCTTGCTGC CAGCTACCTGTATCTGGCACCTCAGCTCCCACCCGCCAGCCAGATCCGCGAGGTGGAATACCAGATTCCCCTGCGCATTT ACAGCAGCGATATGAAGCTAATTGCGGAATATGGAGAAAAGCGCCGACAACCGGTCTCTTACGAGGAACTGCCGGAGGGG CTGATACAGGCCGTACTGGCCGCCGAAGACGAGCGGTTCTTCAGCCATAACGGCGTCGACCTGAAAGGCTTGCTGCGCGC CGCCGTGGAGCTGGCTCGTTATCGGGAGATCCGCTCCGGGGGATCCACGATTACCATGCAGGTGGCCCGAAACTTCTTCC TCAACCGGGACCAGCGCTTCCTTCGCAAATTCAACGAGATCGTTCTGGCCATCCAGATTGAACGGGTACTCGAAAAAGAA GAAATCCTCGAGCTTTACCTGAACAAGATCTATCTGGGGCACCGTGCCTACGGGGCTGAAGCGGCCGCCCAGGTCTACTA CGGCAAATCCGTGGGCGAACTCGATATTGCCCAGCAGGCCATGATCGCCGGCCTGCCCAAGGCGCCCTCCGCCTACAATC CGATCACCAACCCGGAACGGGCACGGGTACGGCGCAACTGGATCCTGTTCCGCATGGAAGAGACCGGCGCGCTGACCCAG GAAGAGCGCATGGCCGCCCAGGCCGAGCCCGTCAGCGCCCGCTTCCATGCCGCACAGCCGGAAGTGGAAGCCGCCTACCT GGGCGAGATGGTGCGCCTGCAAGCCGCCAAACTGGTGGATGACGACATTTTTACCGACGGCATTCGCATCATCACCACCG TGGACAGCCAGCGGCAGAAAGCCGCCGTTCATGCCTTGCGCAACGGTCTTCACAGTTATGATGAGCGCCATGGCTATCGT GGTCCGATCGCCCAGCGGGACCTCAGCGACGCACCCGCCCTGCCTGCGCTCAGCTCCGCCGACAACGAGCAACCGGACGC AGATGACGGCGAACTCCCCAAACAGGAAGACAAGGCGGAAATCGAGAAAACCATTACCGGTCTGGACCCAAGCGTGGCCA GCTGGGCCAAACTGATTCGCGATCAGCGACGCATTGGTCCGCTGCAGCCAGTGATCGTTACCCGTGTCGGCGACCAGGAT GCCGACATCCTGTTCCGTGACGGCAAGCGAGCCAGTCTGGCCTGGGACGACATACGCTGGGCCCGCCCCCAGCTCAACAA CAAGTACGTTGGCGACAAACCGCAGAAAGCCGGGGACGTGCTAACCCGAGGCGATGTGGTCCGCGTTCGCCCAGTGGGCA GCGAAGACAGCCGTCGCTGGCGCCTGGCACAACTGCCCAAAGCCCAGTCAGCTCTGGTTTCACTGGACCCGGCAAACGGC GCTATCGTTGCCATGCAGGGCGGCTACAGCTTCTCGGCATCCAATTTCAACCGGGCCGTACAGAGCGAGCGCCAGGCCGG CTCGGTCTTCAAACCGTTTATCTACACCTCCGCCATGGAGAACGGCTTTACCCCTGCCTCCATCATCAATGATGCGCCCG TGGTCTTCGACGACGACAAGCTGGAAACCGCCTGGCGCCCCACCGGGGCCAGCGGCAAGTTTTACGGCCCCACGCGCATG CGAGAGGCCCTCTACCGCTCCCTGAACCTGGTTTCCATCCGCATCCTTCGCCAGATCGGCATCAGCCAGGCCATGGGCAC GCTGAAGCGCTTTGGCCTGCCGGCAGACACCTTCCAGCGTGATCTGTCCCTGGCTCTGGGGAGCGCCAGCGTGACCCCAC TGGATATTGCCAACGCCTACAGCGTTTTTGCCAACGGCGGCTACCGGGTAACCCCGTGGGCCATTGAGCGCATCGAGAAT GCCAATGGCGATGTTCTCTGGAAAGCACCGGAAGTGATTCTCTGCGAACCTCCCTGCCTGCCGCCTGTGGAACTGCGTGA AGAAACCCAGAACGACAAGCCGACACTGACCGAGATGCGCGACCGCCAGGAAAGCGACGCACCTGACGCACCGCTCAAGA CAATCCAGCCTGCCCCCATCATGGCCCCACGGGTACTCGACCCACGGGTTGCCTGGCTGATGAACTCCATGCTCCAGGAC GTGATTCGCATGGGCACCGGCAGCAAAGCGCGCGCCCTGGGCCGTGACGACCTGGCCGGCAAGACCGGCACCACCAATGA CCAGGTGGATGCCTGGTTCTCCGGCTATTCTCCCGACCTGGTGGCTACCGTCTGGGTCGGTTTTGACAACCCGGCCAACC TGGGCTGGGGCGAGTATGGCGGCAAAGCCGCTCTACCCATCTGGATCGACTATATGGGCCCGGCCCTGCAAGGGGTCGAA GAACGGCAACTGGAACAGCCGTCGGGCATCGCCACCGTCCGCATCGACCCGGACAGCGGCCTGCTGGCACGGCCGGACAA CCCGAATGCCATCCGGGAGTACTTCATTGAGGATCAGGTCCCGGAGCTGGAACCACAGCGAGGCCCCGGGGGCAGCAACA GTGCGCCGGAACAGATTTTCTGA
Upstream 100 bases:
>100_bases ATCAATTCCCTTGGTATGCAAATAAGGGATATTTAAATGGTCTTTATGTGAGCCTATAAATAGGTTCTTCTATCGATCCC AGCCAGTAGTTGTCGAAAAC
Downstream 100 bases:
>100_bases GGGACGTAGATGTTTTTTGTAGTTTATCCACACCACGTTCGGGTTTTCCGCACGCGGTTTACCCGCATGCGGTAAACCCG AACGACTAATAAGTAATAAG
Product: penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 860; Mature: 860
Protein sequence:
>860_residues MRFPPWIRYLLLLLIAGTGGGLSILAASYLYLAPQLPPASQIREVEYQIPLRIYSSDMKLIAEYGEKRRQPVSYEELPEG LIQAVLAAEDERFFSHNGVDLKGLLRAAVELARYREIRSGGSTITMQVARNFFLNRDQRFLRKFNEIVLAIQIERVLEKE EILELYLNKIYLGHRAYGAEAAAQVYYGKSVGELDIAQQAMIAGLPKAPSAYNPITNPERARVRRNWILFRMEETGALTQ EERMAAQAEPVSARFHAAQPEVEAAYLGEMVRLQAAKLVDDDIFTDGIRIITTVDSQRQKAAVHALRNGLHSYDERHGYR GPIAQRDLSDAPALPALSSADNEQPDADDGELPKQEDKAEIEKTITGLDPSVASWAKLIRDQRRIGPLQPVIVTRVGDQD ADILFRDGKRASLAWDDIRWARPQLNNKYVGDKPQKAGDVLTRGDVVRVRPVGSEDSRRWRLAQLPKAQSALVSLDPANG AIVAMQGGYSFSASNFNRAVQSERQAGSVFKPFIYTSAMENGFTPASIINDAPVVFDDDKLETAWRPTGASGKFYGPTRM REALYRSLNLVSIRILRQIGISQAMGTLKRFGLPADTFQRDLSLALGSASVTPLDIANAYSVFANGGYRVTPWAIERIEN ANGDVLWKAPEVILCEPPCLPPVELREETQNDKPTLTEMRDRQESDAPDAPLKTIQPAPIMAPRVLDPRVAWLMNSMLQD VIRMGTGSKARALGRDDLAGKTGTTNDQVDAWFSGYSPDLVATVWVGFDNPANLGWGEYGGKAALPIWIDYMGPALQGVE ERQLEQPSGIATVRIDPDSGLLARPDNPNAIREYFIEDQVPELEPQRGPGGSNSAPEQIF
Sequences:
>Translated_860_residues MRFPPWIRYLLLLLIAGTGGGLSILAASYLYLAPQLPPASQIREVEYQIPLRIYSSDMKLIAEYGEKRRQPVSYEELPEG LIQAVLAAEDERFFSHNGVDLKGLLRAAVELARYREIRSGGSTITMQVARNFFLNRDQRFLRKFNEIVLAIQIERVLEKE EILELYLNKIYLGHRAYGAEAAAQVYYGKSVGELDIAQQAMIAGLPKAPSAYNPITNPERARVRRNWILFRMEETGALTQ EERMAAQAEPVSARFHAAQPEVEAAYLGEMVRLQAAKLVDDDIFTDGIRIITTVDSQRQKAAVHALRNGLHSYDERHGYR GPIAQRDLSDAPALPALSSADNEQPDADDGELPKQEDKAEIEKTITGLDPSVASWAKLIRDQRRIGPLQPVIVTRVGDQD ADILFRDGKRASLAWDDIRWARPQLNNKYVGDKPQKAGDVLTRGDVVRVRPVGSEDSRRWRLAQLPKAQSALVSLDPANG AIVAMQGGYSFSASNFNRAVQSERQAGSVFKPFIYTSAMENGFTPASIINDAPVVFDDDKLETAWRPTGASGKFYGPTRM REALYRSLNLVSIRILRQIGISQAMGTLKRFGLPADTFQRDLSLALGSASVTPLDIANAYSVFANGGYRVTPWAIERIEN ANGDVLWKAPEVILCEPPCLPPVELREETQNDKPTLTEMRDRQESDAPDAPLKTIQPAPIMAPRVLDPRVAWLMNSMLQD VIRMGTGSKARALGRDDLAGKTGTTNDQVDAWFSGYSPDLVATVWVGFDNPANLGWGEYGGKAALPIWIDYMGPALQGVE ERQLEQPSGIATVRIDPDSGLLARPDNPNAIREYFIEDQVPELEPQRGPGGSNSAPEQIF >Mature_860_residues MRFPPWIRYLLLLLIAGTGGGLSILAASYLYLAPQLPPASQIREVEYQIPLRIYSSDMKLIAEYGEKRRQPVSYEELPEG LIQAVLAAEDERFFSHNGVDLKGLLRAAVELARYREIRSGGSTITMQVARNFFLNRDQRFLRKFNEIVLAIQIERVLEKE EILELYLNKIYLGHRAYGAEAAAQVYYGKSVGELDIAQQAMIAGLPKAPSAYNPITNPERARVRRNWILFRMEETGALTQ EERMAAQAEPVSARFHAAQPEVEAAYLGEMVRLQAAKLVDDDIFTDGIRIITTVDSQRQKAAVHALRNGLHSYDERHGYR GPIAQRDLSDAPALPALSSADNEQPDADDGELPKQEDKAEIEKTITGLDPSVASWAKLIRDQRRIGPLQPVIVTRVGDQD ADILFRDGKRASLAWDDIRWARPQLNNKYVGDKPQKAGDVLTRGDVVRVRPVGSEDSRRWRLAQLPKAQSALVSLDPANG AIVAMQGGYSFSASNFNRAVQSERQAGSVFKPFIYTSAMENGFTPASIINDAPVVFDDDKLETAWRPTGASGKFYGPTRM REALYRSLNLVSIRILRQIGISQAMGTLKRFGLPADTFQRDLSLALGSASVTPLDIANAYSVFANGGYRVTPWAIERIEN ANGDVLWKAPEVILCEPPCLPPVELREETQNDKPTLTEMRDRQESDAPDAPLKTIQPAPIMAPRVLDPRVAWLMNSMLQD VIRMGTGSKARALGRDDLAGKTGTTNDQVDAWFSGYSPDLVATVWVGFDNPANLGWGEYGGKAALPIWIDYMGPALQGVE ERQLEQPSGIATVRIDPDSGLLARPDNPNAIREYFIEDQVPELEPQRGPGGSNSAPEQIF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=875, Percent_Identity=40.9142857142857, Blast_Score=607, Evalue=1e-175, Organism=Escherichia coli, GI1786343, Length=336, Percent_Identity=29.1666666666667, Blast_Score=125, Evalue=1e-29, Organism=Escherichia coli, GI1788867, Length=183, Percent_Identity=38.2513661202186, Blast_Score=112, Evalue=7e-26, Organism=Escherichia coli, GI1789601, Length=227, Percent_Identity=30.3964757709251, Blast_Score=89, Evalue=1e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 95332; Mature: 95332
Theoretical pI: Translated: 5.12; Mature: 5.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRFPPWIRYLLLLLIAGTGGGLSILAASYLYLAPQLPPASQIREVEYQIPLRIYSSDMKL CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHEEECEEEECHHHHH IAEYGEKRRQPVSYEELPEGLIQAVLAAEDERFFSHNGVDLKGLLRAAVELARYREIRSG HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC GSTITMQVARNFFLNRDQRFLRKFNEIVLAIQIERVLEKEEILELYLNKIYLGHRAYGAE CCEEEHHHHHHHHCCCHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCH AAAQVYYGKSVGELDIAQQAMIAGLPKAPSAYNPITNPERARVRRNWILFRMEETGALTQ HHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEEEEEECCCCCCH EERMAAQAEPVSARFHAAQPEVEAAYLGEMVRLQAAKLVDDDIFTDGIRIITTVDSQRQK HHHHHHHCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH AAVHALRNGLHSYDERHGYRGPIAQRDLSDAPALPALSSADNEQPDADDGELPKQEDKAE HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH IEKTITGLDPSVASWAKLIRDQRRIGPLQPVIVTRVGDQDADILFRDGKRASLAWDDIRW HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHH ARPQLNNKYVGDKPQKAGDVLTRGDVVRVRPVGSEDSRRWRLAQLPKAQSALVSLDPANG CCCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCCCCCCHHHHCCCHHHHEEEECCCCC AIVAMQGGYSFSASNFNRAVQSERQAGSVFKPFIYTSAMENGFTPASIINDAPVVFDDDK EEEEEECCCEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCC LETAWRPTGASGKFYGPTRMREALYRSLNLVSIRILRQIGISQAMGTLKRFGLPADTFQR CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH DLSLALGSASVTPLDIANAYSVFANGGYRVTPWAIERIENANGDVLWKAPEVILCEPPCL HHHHHHCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHCCCCCCEEEECCCEEEECCCCC PPVELREETQNDKPTLTEMRDRQESDAPDAPLKTIQPAPIMAPRVLDPRVAWLMNSMLQD CCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH VIRMGTGSKARALGRDDLAGKTGTTNDQVDAWFSGYSPDLVATVWVGFDNPANLGWGEYG HHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC GKAALPIWIDYMGPALQGVEERQLEQPSGIATVRIDPDSGLLARPDNPNAIREYFIEDQV CCEECEEEEEHHCHHHCCCHHHHCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHCCC PELEPQRGPGGSNSAPEQIF CCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MRFPPWIRYLLLLLIAGTGGGLSILAASYLYLAPQLPPASQIREVEYQIPLRIYSSDMKL CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHEEECEEEECHHHHH IAEYGEKRRQPVSYEELPEGLIQAVLAAEDERFFSHNGVDLKGLLRAAVELARYREIRSG HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC GSTITMQVARNFFLNRDQRFLRKFNEIVLAIQIERVLEKEEILELYLNKIYLGHRAYGAE CCEEEHHHHHHHHCCCHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCH AAAQVYYGKSVGELDIAQQAMIAGLPKAPSAYNPITNPERARVRRNWILFRMEETGALTQ HHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEEEEEECCCCCCH EERMAAQAEPVSARFHAAQPEVEAAYLGEMVRLQAAKLVDDDIFTDGIRIITTVDSQRQK HHHHHHHCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH AAVHALRNGLHSYDERHGYRGPIAQRDLSDAPALPALSSADNEQPDADDGELPKQEDKAE HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH IEKTITGLDPSVASWAKLIRDQRRIGPLQPVIVTRVGDQDADILFRDGKRASLAWDDIRW HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHH ARPQLNNKYVGDKPQKAGDVLTRGDVVRVRPVGSEDSRRWRLAQLPKAQSALVSLDPANG CCCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCCCCCCHHHHCCCHHHHEEEECCCCC AIVAMQGGYSFSASNFNRAVQSERQAGSVFKPFIYTSAMENGFTPASIINDAPVVFDDDK EEEEEECCCEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCC LETAWRPTGASGKFYGPTRMREALYRSLNLVSIRILRQIGISQAMGTLKRFGLPADTFQR CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH DLSLALGSASVTPLDIANAYSVFANGGYRVTPWAIERIENANGDVLWKAPEVILCEPPCL HHHHHHCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHCCCCCCEEEECCCEEEECCCCC PPVELREETQNDKPTLTEMRDRQESDAPDAPLKTIQPAPIMAPRVLDPRVAWLMNSMLQD CCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH VIRMGTGSKARALGRDDLAGKTGTTNDQVDAWFSGYSPDLVATVWVGFDNPANLGWGEYG HHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC GKAALPIWIDYMGPALQGVEERQLEQPSGIATVRIDPDSGLLARPDNPNAIREYFIEDQV CCEECEEEEEHHCHHHCCCHHHHCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHCCC PELEPQRGPGGSNSAPEQIF CCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10984043; 7901733 [H]