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The map label for this gene is apaH [H]

Identifier: 110834911

GI number: 110834911

Start: 2338742

End: 2339548

Strand: Direct

Name: apaH [H]

Synonym: ABO_2050

Alternate gene names: 110834911

Gene position: 2338742-2339548 (Clockwise)

Preceding gene: 110834910

Following gene: 110834913

Centisome position: 74.96

GC content: 60.1

Gene sequence:

>807_bases
ATGAGCGATTACGCCATTGGCGATCTGCAGGGCTGCCTAGGCGCGTTTGACTGTTTGCTGGAAAAGCTTAGCTTCAATGC
CGACCGCGACCGCCTGTTTCTCGCGGGAGACCTGGTCAACCGGGGGCCGGACTCACTAGGCACCCTGCGGCGCGTCCACG
CCCTGCGCGACAATGTACATACCGTGCTAGGCAACCACGACCTACACCTGCTGGCCGTGGCCAACGGCACCATTCCCAGT
AAACGTAAAGACACTCTCAGCGAAATTTTAAACGCACCGGATCGTGATGAACTGCTGGGCTGGCTACAACAACAACCGCT
GCTTATTAACCTACCAGAACATAATGCAGTGATGACCCACGCCGGCATTCCGCCGCTGTGGTCACTGGCCCAGGCCAGCC
AGCGCGCAGCGGAAGTGGAAACCGTGCTGCGTAACCACTCGGCCGGCACATTTTTTACTCACATGTACGGCAATACCCCC
GCCGGCTGGGACGAGAAGCTGAGTGGCCCAGACCGCTGGCGGGTGATCACCAACCACTTCACCCGCATGCGTTTTGTAGA
TCAGGCCGCAGAGCTGGACCTGACTAGCAAAGGTGAGCCCGACTTGCCCCCCGCCGGGTTCATTCCCTGGTTCCAGCACC
CCGGCCGAATCGTCACCGATACTCGCATCCTGTTCGGCCACTGGGCTGCCCTGCAAGGCCACAGTGGCGTCGACAAGGTC
GACGCACTAGACACCGGGTGCGTGTGGGGAGGGTCCTTAACTGCACTACGGCTAGACGACTTGGTTCGCATTCAGTGCCA
CTGCTAG

Upstream 100 bases:

>100_bases
CCCAACATATGGCCGATGGGGACATCATTGTTTTAGCCCGTAAAAGCGCAAGCGTCGAGCATCAAGCACCCAGCATCAGG
CGTATCACCGGAGACGCCTT

Downstream 100 bases:

>100_bases
GCGTCAGCCTTCGTTAGTTGCTTCAGCTGGCGGCGTATCTTGTGGTCCCCCAGCAGAAACAGCGACAGTGCCAGCACGAT
TAACGCGGCACCCACCAGCA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSDYAIGDLQGCLGAFDCLLEKLSFNADRDRLFLAGDLVNRGPDSLGTLRRVHALRDNVHTVLGNHDLHLLAVANGTIPS
KRKDTLSEILNAPDRDELLGWLQQQPLLINLPEHNAVMTHAGIPPLWSLAQASQRAAEVETVLRNHSAGTFFTHMYGNTP
AGWDEKLSGPDRWRVITNHFTRMRFVDQAAELDLTSKGEPDLPPAGFIPWFQHPGRIVTDTRILFGHWAALQGHSGVDKV
DALDTGCVWGGSLTALRLDDLVRIQCHC

Sequences:

>Translated_268_residues
MSDYAIGDLQGCLGAFDCLLEKLSFNADRDRLFLAGDLVNRGPDSLGTLRRVHALRDNVHTVLGNHDLHLLAVANGTIPS
KRKDTLSEILNAPDRDELLGWLQQQPLLINLPEHNAVMTHAGIPPLWSLAQASQRAAEVETVLRNHSAGTFFTHMYGNTP
AGWDEKLSGPDRWRVITNHFTRMRFVDQAAELDLTSKGEPDLPPAGFIPWFQHPGRIVTDTRILFGHWAALQGHSGVDKV
DALDTGCVWGGSLTALRLDDLVRIQCHC
>Mature_267_residues
SDYAIGDLQGCLGAFDCLLEKLSFNADRDRLFLAGDLVNRGPDSLGTLRRVHALRDNVHTVLGNHDLHLLAVANGTIPSK
RKDTLSEILNAPDRDELLGWLQQQPLLINLPEHNAVMTHAGIPPLWSLAQASQRAAEVETVLRNHSAGTFFTHMYGNTPA
GWDEKLSGPDRWRVITNHFTRMRFVDQAAELDLTSKGEPDLPPAGFIPWFQHPGRIVTDTRILFGHWAALQGHSGVDKVD
ALDTGCVWGGSLTALRLDDLVRIQCHC

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=260, Percent_Identity=50, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 29644; Mature: 29513

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYAIGDLQGCLGAFDCLLEKLSFNADRDRLFLAGDLVNRGPDSLGTLRRVHALRDNVH
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHCCCHHHHHHHHHHHHHHHHH
TVLGNHDLHLLAVANGTIPSKRKDTLSEILNAPDRDELLGWLQQQPLLINLPEHNAVMTH
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEEEE
AGIPPLWSLAQASQRAAEVETVLRNHSAGTFFTHMYGNTPAGWDEKLSGPDRWRVITNHF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
TRMRFVDQAAELDLTSKGEPDLPPAGFIPWFQHPGRIVTDTRILFGHWAALQGHSGVDKV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCEEEECCEEEHHHHHHHCCCCCCCHH
DALDTGCVWGGSLTALRLDDLVRIQCHC
HHCCCCCEECCCEEEEECCCEEEEEECC
>Mature Secondary Structure 
SDYAIGDLQGCLGAFDCLLEKLSFNADRDRLFLAGDLVNRGPDSLGTLRRVHALRDNVH
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHCCCHHHHHHHHHHHHHHHHH
TVLGNHDLHLLAVANGTIPSKRKDTLSEILNAPDRDELLGWLQQQPLLINLPEHNAVMTH
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEEEE
AGIPPLWSLAQASQRAAEVETVLRNHSAGTFFTHMYGNTPAGWDEKLSGPDRWRVITNHF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
TRMRFVDQAAELDLTSKGEPDLPPAGFIPWFQHPGRIVTDTRILFGHWAALQGHSGVDKV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCEEEECCEEEHHHHHHHCCCCCCCHH
DALDTGCVWGGSLTALRLDDLVRIQCHC
HHCCCCCEECCCEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA