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The map label for this gene is apbE [H]

Identifier: 110834863

GI number: 110834863

Start: 2289567

End: 2290472

Strand: Reverse

Name: apbE [H]

Synonym: ABO_2002

Alternate gene names: 110834863

Gene position: 2290472-2289567 (Counterclockwise)

Preceding gene: 110834864

Following gene: 110834862

Centisome position: 73.41

GC content: 54.3

Gene sequence:

>906_bases
ATGACACAGGGGAAAGCATTTACCCTGGAACAGGACGGCGCCCTTTGGCGCGGCCGTTTTTCTGCCATGGCAAGTCCTTG
TGAATGTTTGGTGCGCGGAGTCAGTAAAAGCCAGGCACTGGCACTGTTTGAGTGTGTGACCGAGGAGGCCTGGCGAATCG
AAAGAAAATACTCCCGTTTTCGGCAAGACAATTTGATCGCGGCCATCAATGCTGGAGATGGGCGCTGGGTGGATATTGAT
GATGAGAGCGCCCGGTTACTTGATTTCGCCGGTCAATGTTGGCAGCTCAGTGACGGTGCTTTTGACATCACTTCGGGCGT
ATTACGACGTGCCTGGCACTTTGATGGTTCTAATCGGTTACCGAAACCTGAGCAGGTTGACGCCTTATTATCATTGGTGG
GTTGGAACAAGGTCGAACGGCAGCCAGGAAAAATTCGCTTACAGGCGGGGATGGAACTGGATTTAGGTGGCATTGGTAAA
GAATATGCAGTGGACAGTGCCTTTCAATTGGCCGGCCAATTTACCGATGCGGATGTACTGGTGAATTTTGGGGGTGACCT
AGTCGCGCGTGCTGCGCAGGCACCCTGGCAGGTGGGTATGGAGGGTACAGCCAAGCCTGTTGCCGGGCAGTTGCAGTTCA
CCACCGGTGCGCTGGCGACTAGCGGTGATAGCCGCCGTTTTTTACTTCGTGATGGTGTCCGTTATAGCCATGTGCTGGAT
CCGCGCAGTGGCTGGCCGGTATCCGGTGCGCCTCGTGCTGTTACCGTATATGGGCGCCAATGTACTCAGGCTGGTCTGTT
GTCTACGCTTGCTCTGCTTCAGGGAAAAGACGCTGAAACCCTGTTGCGAGGGGCAGGTGTACAATATTGGATTCAATGGG
GGAATGATGCGCCTATTGCTGGTTGA

Upstream 100 bases:

>100_bases
AGTTTCCAGCAGAGCGGCGACAGTGATGCTTCGGAACTCGATGCACTGATCACGCAGGTCGGGTATACATTCTACTGGTA
GTCGTTGCGGTGGAGTCTCT

Downstream 100 bases:

>100_bases
GAATGATGTGCTGCTAGCAGATGGCCTGCAACGTGCGCTCCGGGCTGAAGGCTATACGGTGGATCATATCGATCGGGGTG
ATCTGTTGATGCCGGCTCTG

Product: thiamine biosynthesis lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTQGKAFTLEQDGALWRGRFSAMASPCECLVRGVSKSQALALFECVTEEAWRIERKYSRFRQDNLIAAINAGDGRWVDID
DESARLLDFAGQCWQLSDGAFDITSGVLRRAWHFDGSNRLPKPEQVDALLSLVGWNKVERQPGKIRLQAGMELDLGGIGK
EYAVDSAFQLAGQFTDADVLVNFGGDLVARAAQAPWQVGMEGTAKPVAGQLQFTTGALATSGDSRRFLLRDGVRYSHVLD
PRSGWPVSGAPRAVTVYGRQCTQAGLLSTLALLQGKDAETLLRGAGVQYWIQWGNDAPIAG

Sequences:

>Translated_301_residues
MTQGKAFTLEQDGALWRGRFSAMASPCECLVRGVSKSQALALFECVTEEAWRIERKYSRFRQDNLIAAINAGDGRWVDID
DESARLLDFAGQCWQLSDGAFDITSGVLRRAWHFDGSNRLPKPEQVDALLSLVGWNKVERQPGKIRLQAGMELDLGGIGK
EYAVDSAFQLAGQFTDADVLVNFGGDLVARAAQAPWQVGMEGTAKPVAGQLQFTTGALATSGDSRRFLLRDGVRYSHVLD
PRSGWPVSGAPRAVTVYGRQCTQAGLLSTLALLQGKDAETLLRGAGVQYWIQWGNDAPIAG
>Mature_300_residues
TQGKAFTLEQDGALWRGRFSAMASPCECLVRGVSKSQALALFECVTEEAWRIERKYSRFRQDNLIAAINAGDGRWVDIDD
ESARLLDFAGQCWQLSDGAFDITSGVLRRAWHFDGSNRLPKPEQVDALLSLVGWNKVERQPGKIRLQAGMELDLGGIGKE
YAVDSAFQLAGQFTDADVLVNFGGDLVARAAQAPWQVGMEGTAKPVAGQLQFTTGALATSGDSRRFLLRDGVRYSHVLDP
RSGWPVSGAPRAVTVYGRQCTQAGLLSTLALLQGKDAETLLRGAGVQYWIQWGNDAPIAG

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=210, Percent_Identity=30.952380952381, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 32752; Mature: 32621

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQGKAFTLEQDGALWRGRFSAMASPCECLVRGVSKSQALALFECVTEEAWRIERKYSRF
CCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RQDNLIAAINAGDGRWVDIDDESARLLDFAGQCWQLSDGAFDITSGVLRRAWHFDGSNRL
CCCCEEEEEECCCCCEEEECCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCCCC
PKPEQVDALLSLVGWNKVERQPGKIRLQAGMELDLGGIGKEYAVDSAFQLAGQFTDADVL
CCHHHHHHHHHHHCCCHHCCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHCCCCCCEEE
VNFGGDLVARAAQAPWQVGMEGTAKPVAGQLQFTTGALATSGDSRRFLLRDGVRYSHVLD
EECCCHHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCEEECCCCCEEHHHCCCCCEEEEC
PRSGWPVSGAPRAVTVYGRQCTQAGLLSTLALLQGKDAETLLRGAGVQYWIQWGNDAPIA
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECCCCCCC
G
C
>Mature Secondary Structure 
TQGKAFTLEQDGALWRGRFSAMASPCECLVRGVSKSQALALFECVTEEAWRIERKYSRF
CCCCEEEEECCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RQDNLIAAINAGDGRWVDIDDESARLLDFAGQCWQLSDGAFDITSGVLRRAWHFDGSNRL
CCCCEEEEEECCCCCEEEECCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCCCC
PKPEQVDALLSLVGWNKVERQPGKIRLQAGMELDLGGIGKEYAVDSAFQLAGQFTDADVL
CCHHHHHHHHHHHCCCHHCCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHCCCCCCEEE
VNFGGDLVARAAQAPWQVGMEGTAKPVAGQLQFTTGALATSGDSRRFLLRDGVRYSHVLD
EECCCHHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCEEECCCCCEEHHHCCCCCEEEEC
PRSGWPVSGAPRAVTVYGRQCTQAGLLSTLALLQGKDAETLLRGAGVQYWIQWGNDAPIA
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]