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The map label for this gene is lip [H]

Identifier: 110834836

GI number: 110834836

Start: 2253418

End: 2254380

Strand: Direct

Name: lip [H]

Synonym: ABO_1975

Alternate gene names: 110834836

Gene position: 2253418-2254380 (Clockwise)

Preceding gene: 110834832

Following gene: 110834837

Centisome position: 72.22

GC content: 53.69

Gene sequence:

>963_bases
ATGTCGATCATCCTCCGACGCCTGGTCATGGTCACCGCTTTGCTATTCAGCACCAGCCAGACGCAAGCCTGGTCCTGGTT
GGGAAAAGACAAAGACACAAGCTATGCAAACACTCGCTACCCCATTGTTCTGGTGGGCGGCCTCATTGCTTTTGATGATA
TTGCCGGTATCGATTATTTCTACGGTATCGCTGATGATATGCGCGATTACGGCGCCGAAGTCTACGAGAGTAATGTAAGC
GCACTACAAAGCAATGAATACCGCGGTGAAGAATTAATCATCCAGATTGAAAATTATCTAGCCGTCACAGGTGCAACAAA
AGTGAATCTTGTCGGCCATTCTCAAGGGGCGGGCACGGCGCGATATGTTGCCGCCGTTCGTCCGGACATCATCGCATCGG
TCACCTCAGTGCACGGTGAAAATCGTGGAACTCCTGTTGCTGACATCCTTCGCGGGTTGATACCGCAAGGCAGTGCAGCG
GAAGAGCTCGCAGACATGGTTGCCAACGGGTTTGGGTTCCTATGGGAGTTAGCATCCGGGGGGCCCAACGCAAAGAGTCA
ATCCACCAAAGCGGTGCTCGTGGCGTCAACCACCGAAGGCATGGCCGCGTTCAACCAGCGCTACCCTCAAGCCATGCCCA
CCTCCGCCTGCGGCACTAGTGGTGAACATGCGGTCAACGGAGTGCGTTACTGGTCTTGGGGAGGCACAGGTGTGCGCACC
AACCTACTCGATCCCTTCGATAGTGTATTGGTCACCGTCACCCAGTTTGCCTTCTCATCTGGGGTTGAACATGACGGCGT
GCTGCCCCTGTGCGGTATGTACCTTGGCAAACCCATTCGACATGACTATCGCCATAACCATGCGGATGCTATCCGCCAGC
TGTTTGGTTTGCTTGGCTGGGAAACTGATCCCAAAACATTATATCGCAACCACGCTAACCGCCTGAAAAATGCAGGACTT
TAA

Upstream 100 bases:

>100_bases
CATTCTAGTTGAGTCCAAGTACACTCCTGTGCGCCATCACAAATATAAATATAAACTCAGCCTTTACACTGGCTATAACC
TAATACAATAAGAGGCAGCC

Downstream 100 bases:

>100_bases
CAAGCATTCCCTCAGAGGGTCGCTCTTTACAGGACCCTCTGCATTGAGTCTGAGTCATGACACGAACATTTGTTCTACTT
ATCGCAATAGTGCTCTCAGC

Product: lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSIILRRLVMVTALLFSTSQTQAWSWLGKDKDTSYANTRYPIVLVGGLIAFDDIAGIDYFYGIADDMRDYGAEVYESNVS
ALQSNEYRGEELIIQIENYLAVTGATKVNLVGHSQGAGTARYVAAVRPDIIASVTSVHGENRGTPVADILRGLIPQGSAA
EELADMVANGFGFLWELASGGPNAKSQSTKAVLVASTTEGMAAFNQRYPQAMPTSACGTSGEHAVNGVRYWSWGGTGVRT
NLLDPFDSVLVTVTQFAFSSGVEHDGVLPLCGMYLGKPIRHDYRHNHADAIRQLFGLLGWETDPKTLYRNHANRLKNAGL

Sequences:

>Translated_320_residues
MSIILRRLVMVTALLFSTSQTQAWSWLGKDKDTSYANTRYPIVLVGGLIAFDDIAGIDYFYGIADDMRDYGAEVYESNVS
ALQSNEYRGEELIIQIENYLAVTGATKVNLVGHSQGAGTARYVAAVRPDIIASVTSVHGENRGTPVADILRGLIPQGSAA
EELADMVANGFGFLWELASGGPNAKSQSTKAVLVASTTEGMAAFNQRYPQAMPTSACGTSGEHAVNGVRYWSWGGTGVRT
NLLDPFDSVLVTVTQFAFSSGVEHDGVLPLCGMYLGKPIRHDYRHNHADAIRQLFGLLGWETDPKTLYRNHANRLKNAGL
>Mature_319_residues
SIILRRLVMVTALLFSTSQTQAWSWLGKDKDTSYANTRYPIVLVGGLIAFDDIAGIDYFYGIADDMRDYGAEVYESNVSA
LQSNEYRGEELIIQIENYLAVTGATKVNLVGHSQGAGTARYVAAVRPDIIASVTSVHGENRGTPVADILRGLIPQGSAAE
ELADMVANGFGFLWELASGGPNAKSQSTKAVLVASTTEGMAAFNQRYPQAMPTSACGTSGEHAVNGVRYWSWGGTGVRTN
LLDPFDSVLVTVTQFAFSSGVEHDGVLPLCGMYLGKPIRHDYRHNHADAIRQLFGLLGWETDPKTLYRNHANRLKNAGL

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Lipase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 34656; Mature: 34525

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILRRLVMVTALLFSTSQTQAWSWLGKDKDTSYANTRYPIVLVGGLIAFDDIAGIDYF
CHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHCCHHHH
YGIADDMRDYGAEVYESNVSALQSNEYRGEELIIQIENYLAVTGATKVNLVGHSQGAGTA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEEEECCCEEEEEECCCCCCHH
RYVAAVRPDIIASVTSVHGENRGTPVADILRGLIPQGSAAEELADMVANGFGFLWELASG
HHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
GPNAKSQSTKAVLVASTTEGMAAFNQRYPQAMPTSACGTSGEHAVNGVRYWSWGGTGVRT
CCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCC
NLLDPFDSVLVTVTQFAFSSGVEHDGVLPLCGMYLGKPIRHDYRHNHADAIRQLFGLLGW
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCC
ETDPKTLYRNHANRLKNAGL
CCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIILRRLVMVTALLFSTSQTQAWSWLGKDKDTSYANTRYPIVLVGGLIAFDDIAGIDYF
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHCCHHHH
YGIADDMRDYGAEVYESNVSALQSNEYRGEELIIQIENYLAVTGATKVNLVGHSQGAGTA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEEEECCCEEEEEECCCCCCHH
RYVAAVRPDIIASVTSVHGENRGTPVADILRGLIPQGSAAEELADMVANGFGFLWELASG
HHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
GPNAKSQSTKAVLVASTTEGMAAFNQRYPQAMPTSACGTSGEHAVNGVRYWSWGGTGVRT
CCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCC
NLLDPFDSVLVTVTQFAFSSGVEHDGVLPLCGMYLGKPIRHDYRHNHADAIRQLFGLLGW
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCC
ETDPKTLYRNHANRLKNAGL
CCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]