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The map label for this gene is rlmH

Identifier: 110834815

GI number: 110834815

Start: 2233781

End: 2234263

Strand: Direct

Name: rlmH

Synonym: ABO_1954

Alternate gene names: 110834815

Gene position: 2233781-2234263 (Clockwise)

Preceding gene: 110834814

Following gene: 110834816

Centisome position: 71.59

GC content: 59.42

Gene sequence:

>483_bases
ATGCACCTTGTTCTGCTGGCCATCGGCACCCGCATGCCAGCGTGGGTCACCGAAGGTTTTAACGAATACCAGAAGCGTAT
GCCTCCGGATATGCGCTTAACACTGGAAGAGATTCCCATGCCTAAACGTGGCAAGGGAGACGCCGGCAGTCAAATACGGG
CAGAAGCTGACGCCCTACGCAAGCGCCTGGAAACAATTGTGAAAAAAAGCCCGGGCGCCAAAACCGTGGCGCTGGAAGTC
AACGGCCGGGCGCTGGACACTCACGCCCTTAGCCGTAAACTGGGCGAGCTAAAAGACGTGGGCCAGGATTTAGTGCTGCT
GGTGGGCGGGCCCGATGGCCTGTGCCCCGAGTTATCAGCCAGCGCCCATGAGCGCTGGAGTCTGTCCAACCTGACATTGC
CCCACCCACTGGTGCGAGTATTGTTGGCTGAGCAGCTCTACCGGGGCTGGACACTACTGACCGGGCACCCCTATCACCGT
TGA

Upstream 100 bases:

>100_bases
CCTGATGCTGCCCGCCACCCGTGAATTCTACGATTTGGAACGGCTGTGGAAGAACCCCCAGCACCACCCAGACCGCGAAC
AGCAGCAAGACCACTAGCCC

Downstream 100 bases:

>100_bases
ATAGCGACAAACTCCACGCTACAACACGAGAGGCGCCATGCTAACTGGCAAAGCGTTAATAACGCGCTGCATGGTCAGTT
TGCGATACTAAAGATCAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MHLVLLAIGTRMPAWVTEGFNEYQKRMPPDMRLTLEEIPMPKRGKGDAGSQIRAEADALRKRLETIVKKSPGAKTVALEV
NGRALDTHALSRKLGELKDVGQDLVLLVGGPDGLCPELSASAHERWSLSNLTLPHPLVRVLLAEQLYRGWTLLTGHPYHR

Sequences:

>Translated_160_residues
MHLVLLAIGTRMPAWVTEGFNEYQKRMPPDMRLTLEEIPMPKRGKGDAGSQIRAEADALRKRLETIVKKSPGAKTVALEV
NGRALDTHALSRKLGELKDVGQDLVLLVGGPDGLCPELSASAHERWSLSNLTLPHPLVRVLLAEQLYRGWTLLTGHPYHR
>Mature_160_residues
MHLVLLAIGTRMPAWVTEGFNEYQKRMPPDMRLTLEEIPMPKRGKGDAGSQIRAEADALRKRLETIVKKSPGAKTVALEV
NGRALDTHALSRKLGELKDVGQDLVLLVGGPDGLCPELSASAHERWSLSNLTLPHPLVRVLLAEQLYRGWTLLTGHPYHR

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=160, Percent_Identity=48.125, Blast_Score=146, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_ALCBS (Q0VN46)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693674.1
- ProteinModelPortal:   Q0VN46
- SMR:   Q0VN46
- STRING:   Q0VN46
- GeneID:   4212307
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1954
- NMPDR:   fig|393595.12.peg.1955
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- PhylomeDB:   Q0VN46
- BioCyc:   ABOR393595:ABO_1954-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR016051
- InterPro:   IPR003742
- PIRSF:   PIRSF004505
- TIGRFAMs:   TIGR00246

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17757; Mature: 17757

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLVLLAIGTRMPAWVTEGFNEYQKRMPPDMRLTLEEIPMPKRGKGDAGSQIRAEADALR
CEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCHHHHHHHHHH
KRLETIVKKSPGAKTVALEVNGRALDTHALSRKLGELKDVGQDLVLLVGGPDGLCPELSA
HHHHHHHHCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
SAHERWSLSNLTLPHPLVRVLLAEQLYRGWTLLTGHPYHR
CCHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MHLVLLAIGTRMPAWVTEGFNEYQKRMPPDMRLTLEEIPMPKRGKGDAGSQIRAEADALR
CEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCHHHHHHHHHH
KRLETIVKKSPGAKTVALEVNGRALDTHALSRKLGELKDVGQDLVLLVGGPDGLCPELSA
HHHHHHHHCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
SAHERWSLSNLTLPHPLVRVLLAEQLYRGWTLLTGHPYHR
CCHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA