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The map label for this gene is blh [H]

Identifier: 110834802

GI number: 110834802

Start: 2218599

End: 2219465

Strand: Direct

Name: blh [H]

Synonym: ABO_1941

Alternate gene names: 110834802

Gene position: 2218599-2219465 (Clockwise)

Preceding gene: 110834801

Following gene: 110834803

Centisome position: 71.11

GC content: 55.59

Gene sequence:

>867_bases
ATGTCACGCCCTGAAGTCAAAGCGTTCTTTGACCACGACACTAATACAATCAGCTATGTCGTTACCGACCCGCAAAGCCG
CCACTGCGCCATCGTAGACTCTGTACTGGATTACGACCCCAGCGCGGGTCGCACCCGACACACCAGTGCCGAGCAAATCG
TTAACTACGTGAAACAAGAAAGTCTCACCGTGGATTGGCTGCTGGAAACCCACGTCCATGCTGACCACCTTTCCGCCGCA
CCTTGGATTCAACAACAGGTAGGTGGCCAGCTGGCCATTGGCGAGCACATCAGCACCGTGCAGGAAACCTTTAGCAAGAT
CTTTAACGCCGGCACCGAGTTTGCCCGCGACGGTAGTCAGTTCGATCATCTGTTCAAGGATGGTGAGACTTACAAAGTAG
GGAATCTGCAGGCTCGAGCCATTCACACGCCTGGGCACACCCCGGCTTGCATGAGCCACGTGATCGGCGATTCGGTCTTC
GTCGGGGACACCTTGTTCATGCCAGACTACGGCACCGCCCGCTGCGATTTTCCCGGTGGAGATGCTCGCACTCTATACCA
TTCCATTCAGAAGTTACTCGCTCTGCCGGACGAAACCCGCATGTTTCTGTGCCACGACTACCTACCAGAGAACCGCGAAG
AATTCGTTTGGGAAACCACCGTGGGTGATCAGCGCAAACACAACATTCATGTTCATGAAGGCGTCAGCGAAGAAGAGTTC
GTCACCATGCGAGAAACCCGCGATGCCTCCCTGGACATGCCGCGCCTAATCCTGCCATCGGTGCAGATCAACATGCGCGC
CGGGCACCTTCCTCCCGAGGAAGACAATGGCATCAGCTACCTGAAAATCCCCCTGAACGCACTCTAA

Upstream 100 bases:

>100_bases
GCCCAATATTCCATTATGATATATGCTTATTCCTTAATTTGACTTTGTTCTCCGGCCAGCCTATAACAGTGGCATTGTCG
CATCCTAACGGGAGAGCACC

Downstream 100 bases:

>100_bases
GAGAATGCCCATGCCAGTTGATGACTCTGTCTGGGATGTGGTGATTGTGGGCGGCGGCGCTGCCGGCCTCGCGGCGGCGG
CCAGCCTGCTCAAACGCAAG

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSRPEVKAFFDHDTNTISYVVTDPQSRHCAIVDSVLDYDPSAGRTRHTSAEQIVNYVKQESLTVDWLLETHVHADHLSAA
PWIQQQVGGQLAIGEHISTVQETFSKIFNAGTEFARDGSQFDHLFKDGETYKVGNLQARAIHTPGHTPACMSHVIGDSVF
VGDTLFMPDYGTARCDFPGGDARTLYHSIQKLLALPDETRMFLCHDYLPENREEFVWETTVGDQRKHNIHVHEGVSEEEF
VTMRETRDASLDMPRLILPSVQINMRAGHLPPEEDNGISYLKIPLNAL

Sequences:

>Translated_288_residues
MSRPEVKAFFDHDTNTISYVVTDPQSRHCAIVDSVLDYDPSAGRTRHTSAEQIVNYVKQESLTVDWLLETHVHADHLSAA
PWIQQQVGGQLAIGEHISTVQETFSKIFNAGTEFARDGSQFDHLFKDGETYKVGNLQARAIHTPGHTPACMSHVIGDSVF
VGDTLFMPDYGTARCDFPGGDARTLYHSIQKLLALPDETRMFLCHDYLPENREEFVWETTVGDQRKHNIHVHEGVSEEEF
VTMRETRDASLDMPRLILPSVQINMRAGHLPPEEDNGISYLKIPLNAL
>Mature_287_residues
SRPEVKAFFDHDTNTISYVVTDPQSRHCAIVDSVLDYDPSAGRTRHTSAEQIVNYVKQESLTVDWLLETHVHADHLSAAP
WIQQQVGGQLAIGEHISTVQETFSKIFNAGTEFARDGSQFDHLFKDGETYKVGNLQARAIHTPGHTPACMSHVIGDSVFV
GDTLFMPDYGTARCDFPGGDARTLYHSIQKLLALPDETRMFLCHDYLPENREEFVWETTVGDQRKHNIHVHEGVSEEEFV
TMRETRDASLDMPRLILPSVQINMRAGHLPPEEDNGISYLKIPLNAL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=266, Percent_Identity=27.4436090225564, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538952, Length=268, Percent_Identity=24.2537313432836, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330176, Length=280, Percent_Identity=28.9285714285714, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32427; Mature: 32295

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPEVKAFFDHDTNTISYVVTDPQSRHCAIVDSVLDYDPSAGRTRHTSAEQIVNYVKQE
CCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
SLTVDWLLETHVHADHLSAAPWIQQQVGGQLAIGEHISTVQETFSKIFNAGTEFARDGSQ
CCEEEEHHHHHCCHHHCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCHHHHCCCHH
FDHLFKDGETYKVGNLQARAIHTPGHTPACMSHVIGDSVFVGDTLFMPDYGTARCDFPGG
HHHHHCCCCEEEECCEEEEEEECCCCCHHHHHHHHCCCEEECCEEECCCCCCEECCCCCC
DARTLYHSIQKLLALPDETRMFLCHDYLPENREEFVWETTVGDQRKHNIHVHEGVSEEEF
CHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHEEEECCCCCCCCCEEEEECCCCHHHE
VTMRETRDASLDMPRLILPSVQINMRAGHLPPEEDNGISYLKIPLNAL
EEHHHCCCCCCCCCCEECCCEEEEEECCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SRPEVKAFFDHDTNTISYVVTDPQSRHCAIVDSVLDYDPSAGRTRHTSAEQIVNYVKQE
CCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
SLTVDWLLETHVHADHLSAAPWIQQQVGGQLAIGEHISTVQETFSKIFNAGTEFARDGSQ
CCEEEEHHHHHCCHHHCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCHHHHCCCHH
FDHLFKDGETYKVGNLQARAIHTPGHTPACMSHVIGDSVFVGDTLFMPDYGTARCDFPGG
HHHHHCCCCEEEECCEEEEEEECCCCCHHHHHHHHCCCEEECCEEECCCCCCEECCCCCC
DARTLYHSIQKLLALPDETRMFLCHDYLPENREEFVWETTVGDQRKHNIHVHEGVSEEEF
CHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHEEEECCCCCCCCCEEEEECCCCHHHE
VTMRETRDASLDMPRLILPSVQINMRAGHLPPEEDNGISYLKIPLNAL
EEHHHCCCCCCCCCCEECCCEEEEEECCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]