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The map label for this gene is corC [H]

Identifier: 110834798

GI number: 110834798

Start: 2213028

End: 2213915

Strand: Direct

Name: corC [H]

Synonym: ABO_1937

Alternate gene names: 110834798

Gene position: 2213028-2213915 (Clockwise)

Preceding gene: 110834797

Following gene: 110834799

Centisome position: 70.93

GC content: 54.95

Gene sequence:

>888_bases
ATGTCGGACGATTTTTCGGATAACGGTACCAGCCGAAGTTGGTTGGAGCGTGTCGGCCAGTTTTTCTCACCCACCCCGGG
TGACCGCAACGAACTACTGGAACTGATGCGCTCCATGCGCGACACCCACATCATCGACGGCGACACCCTAGGGATCATCG
AAGGCGCCATCTGCGTGGCAGACATGCAGGTTCGCGAAATCATGATCCCCCGTTCGCAAATGGTCAGCATCAAGGCCAGC
TCCGACCCACGAGGTTTTCTGCCCACCATTATTGACTGCGCACACTCTCGCTTCCCGGTGCTCGGTGACGACCCGGACGA
AGTGATCGGCATCCTCCTTGCCAAGGATCTTTTACCGTTGATCCTTGATCCCGCCCGTATGGAACGTTTTGCGATCAAGG
ATCACATTCGTTCGGCTATGGTGGTGCCTGAGTCAAAGCGTCTGGATTCTCTGCTGCGCGAATTCCGTATCAGCCGCAAT
CACATGGCCATCGTCGTTAACGAATACGGTGGCGTCGCCGGGCTGGTTACCATTGAAGACGTATTGGAACAGATCGTCGG
CGAAATCGAAGACGAACACGACATCGAAGAAGATGACTACCTGATCAAGGATCTGGATAAAAACGAATATACCGTCAAGG
CCCTGACTCCCATCGACGACTTCAACGAACACTTTCATTGCCAGTTCAGCAATGAAGAGTTCGACACCATCGGGGGATTG
GTAATGCAGAAGTTCGGCCGCCTACCAGGCCGCGATGAAAGTATCACTCTGGATGGCTTCCGCGTCACCGTGCTCAGTGC
CGACGGCCGCACAATAAGACTGCTACGGGTAACACCGCCGGGGGATAACGATAATGACGACACCAACCACGGCGCAGACA
ACGGCTGA

Upstream 100 bases:

>100_bases
TGGAAATCCGTGCCCTTGGCGAGTTGGGTTTTCCTGATCCTTACAGCCCTGCGCAACAAGAAAGCCAGGCACAACCTGAA
AATACGGAGCTTAACCCCTG

Downstream 100 bases:

>100_bases
CCCAACCGCGCCTGCCTGGCGCAACGGCCCCTGGGTAATGGCCTTAGTGGCCATTGCCCTGATCGCCGGCCAACTCTTCA
ACAACGCGAACACCCCCCAA

Product: metal ion transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSDDFSDNGTSRSWLERVGQFFSPTPGDRNELLELMRSMRDTHIIDGDTLGIIEGAICVADMQVREIMIPRSQMVSIKAS
SDPRGFLPTIIDCAHSRFPVLGDDPDEVIGILLAKDLLPLILDPARMERFAIKDHIRSAMVVPESKRLDSLLREFRISRN
HMAIVVNEYGGVAGLVTIEDVLEQIVGEIEDEHDIEEDDYLIKDLDKNEYTVKALTPIDDFNEHFHCQFSNEEFDTIGGL
VMQKFGRLPGRDESITLDGFRVTVLSADGRTIRLLRVTPPGDNDNDDTNHGADNG

Sequences:

>Translated_295_residues
MSDDFSDNGTSRSWLERVGQFFSPTPGDRNELLELMRSMRDTHIIDGDTLGIIEGAICVADMQVREIMIPRSQMVSIKAS
SDPRGFLPTIIDCAHSRFPVLGDDPDEVIGILLAKDLLPLILDPARMERFAIKDHIRSAMVVPESKRLDSLLREFRISRN
HMAIVVNEYGGVAGLVTIEDVLEQIVGEIEDEHDIEEDDYLIKDLDKNEYTVKALTPIDDFNEHFHCQFSNEEFDTIGGL
VMQKFGRLPGRDESITLDGFRVTVLSADGRTIRLLRVTPPGDNDNDDTNHGADNG
>Mature_294_residues
SDDFSDNGTSRSWLERVGQFFSPTPGDRNELLELMRSMRDTHIIDGDTLGIIEGAICVADMQVREIMIPRSQMVSIKASS
DPRGFLPTIIDCAHSRFPVLGDDPDEVIGILLAKDLLPLILDPARMERFAIKDHIRSAMVVPESKRLDSLLREFRISRNH
MAIVVNEYGGVAGLVTIEDVLEQIVGEIEDEHDIEEDDYLIKDLDKNEYTVKALTPIDDFNEHFHCQFSNEEFDTIGGLV
MQKFGRLPGRDESITLDGFRVTVLSADGRTIRLLRVTPPGDNDNDDTNHGADNG

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=199, Percent_Identity=30.1507537688442, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786879, Length=266, Percent_Identity=51.5037593984962, Blast_Score=240, Evalue=9e-65,
Organism=Escherichia coli, GI1790664, Length=231, Percent_Identity=27.7056277056277, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082033, Length=190, Percent_Identity=30.5263157894737, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693175, Length=229, Percent_Identity=24.8908296943231, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788119, Length=238, Percent_Identity=29.8319327731092, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33083; Mature: 32952

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDFSDNGTSRSWLERVGQFFSPTPGDRNELLELMRSMRDTHIIDGDTLGIIEGAICVA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHH
DMQVREIMIPRSQMVSIKASSDPRGFLPTIIDCAHSRFPVLGDDPDEVIGILLAKDLLPL
HHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ILDPARMERFAIKDHIRSAMVVPESKRLDSLLREFRISRNHMAIVVNEYGGVAGLVTIED
HCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEHHH
VLEQIVGEIEDEHDIEEDDYLIKDLDKNEYTVKALTPIDDFNEHFHCQFSNEEFDTIGGL
HHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEECCCHHCCCCEEEEECCCCHHHHHHH
VMQKFGRLPGRDESITLDGFRVTVLSADGRTIRLLRVTPPGDNDNDDTNHGADNG
HHHHHCCCCCCCCEEEECCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDDFSDNGTSRSWLERVGQFFSPTPGDRNELLELMRSMRDTHIIDGDTLGIIEGAICVA
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHH
DMQVREIMIPRSQMVSIKASSDPRGFLPTIIDCAHSRFPVLGDDPDEVIGILLAKDLLPL
HHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ILDPARMERFAIKDHIRSAMVVPESKRLDSLLREFRISRNHMAIVVNEYGGVAGLVTIED
HCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEHHH
VLEQIVGEIEDEHDIEEDDYLIKDLDKNEYTVKALTPIDDFNEHFHCQFSNEEFDTIGGL
HHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEECCCHHCCCCEEEEECCCCHHHHHHH
VMQKFGRLPGRDESITLDGFRVTVLSADGRTIRLLRVTPPGDNDNDDTNHGADNG
HHHHHCCCCCCCCEEEECCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]